Ecotoxicity and Human Health: A Biological Approach to Environmental Remediation, 1st Edition (Hardback) book cover

Ecotoxicity and Human Health

A Biological Approach to Environmental Remediation, 1st Edition

By Arthur D. Bloom, Frederick de Serres

CRC Press

336 pages

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Hardback: 9781566701419
pub: 1995-10-09
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Ecotoxicity and Human Health emphasizes the relationships between toxicity, ecological systems, and human health. It focuses on the extent and nature of hazardous waste sites and how their effects may be studied in humans and other systems, using in vitro models, biomarkers of cellular and molecular damage, and animal models. It also includes considerable information on bioremediation, legal and regulatory issues, public perceptions and societal responses, quantitative modeling and analysis, and international directives.

One of the unique features of Ecotoxicity and Human Health is its coverage of the legislative actions that have occurred over the past two decades and which have most affected the issue of hazardous waste. The book discusses the Superfund Statute, the Resource Conservation and Recovery Act (RCRA), the Toxic Substances Control Act (TSCA), the Ocean Dumping Act of 1972, the Rio Conference, United Nations Declarations, EC Regulations and Directives, and selected state legislation.

Table of Contents

Introduction, F.J. de Serres and A.D. Bloom

Hazardous Waste: Nature, Extent, Effects, and Societal Responses, B.L. Johnson


Nature and Extent of Waste Generation

Effects of Hazardous Waste on Human Health

Effects of Hazardous Waste on Ecosystems

Societal Response: Laws and International Conventions

Remediation of Hazardous Wastes

Societal Response: Environmental Ethics

Summary and Conclusions



Ecotoxicology: Environmental Fate and Ecosystem Impact, C.E. Weinstein

The Relationship Between Human and Ecological Health

Biological Interactions with Environmental Contaminants


Ecotoxicology and Biota

Ecosystem Effects of Persistent Toxicants

Considerations for Bioremediation


Integration of Complex Mixture Toxicity and Microbiological Analyses for Environmental Remediation Research, L.D. Claxton, V.S. Houk, and S.E. George

Understanding the Problems

Effect of the Dynamic Complexity of Hazardous Waste Sites Upon Understanding Potential Toxic Exposures

Research Strategies for Microorganisms

Impact of Integrated Biological Analyses Upon Exposure and Risk Assessment Methods

Summary and Conclusions



Biomarkers of DNA Damage, L.R. Shugart

Biomarkers: An Overview

DNA Damage as a Biomarker

Strategies for Biomarker Use

Strategies for Biomarker Evaluation

In Situ Studies




In Situ Evaluation of Genetic Hazards of Complex Chemical Mixtures, S.S. Sandhu, W.R. Lower, and Y.R. Ahuja


Detection of Genetic Hazards at Industrial Waste Sites

Genotoxicity Assessment in Aquatic Environments

Integration, Interpretation, and Limitation of Data



Wildlife Toxicity in Biomonitoring and Bioremediation: Implications for Human Health, K. McBee and R.L. Lochmiller


Population Dynamics

Mixed Function Oxidase (MFO) Enzyme System



Extrapolation from Wildlife Models to Potential Human Effect


Environmental Bioremediation: Approaches and Processes, C. Bonaventura, J. Bonaventura, and D.F. Bodishbaugh

Bioremediation Defined

Bioremediation as a Natural Process

Environmental Health and Human Health Aspects of Environmental Contamination

General Steps and Methods in Bioremediation

Assessment of Bioremediation and Biodegradation

Summary and Conclusions


Environmental Bioremediation: Applications and New Horizons, C. Bonaventura, J. Bonaventura, and D.F. Bodishbaugh

Practical Bioremediation

Bioremediation Technologies in Practice

Future Prospects for Environmental Bioremediation

Research Needed to Advance Bioremediation Technologies

Summary and Conclusions


Quantitative Modeling and Analysis in Environmental Studies, D.P. Gaver


Modeling Groundwater: A Specific System Relevant to Remediation Issues

Compartment and Pharmacokinetic Models

Human Exposure Modeling and Analysis

Dose-Response Models

Risk Assessment

Epidemiologic Case Studies

Summary and Conclusions



Legal and International Considerations: One World, B.L. Johnson and D. Weimer


Fictional Case Study: Goodeworks, Incorporated

U.S. Federal Legislation

Illustrative State Legislation

International Directives and Agreements

Summary and Conclusions




Profiles of Major U.S. Environmental Legislation

Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Environmental Science