Evolving Neural Crest Cells: 1st Edition (Hardback) book cover

Evolving Neural Crest Cells

1st Edition

Edited by Brian Frank Eames, Daniel Meulemans Medeiros, Igor Adameyko

CRC Press

352 pages | 37 Color Illus. | 1 B/W Illus.

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Hardback: 9781138630819
pub: 2020-07-29
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Vertebrates possess lineage-specific characteristics. These include paired anterior sense organs and a robust, modular head skeleton built of cellular cartilage and bone. All of these structures are derived, at least partly, from an embryonic tissue unique vertebrates - the neural crest. The evolutionary history of the neural crest, and neural crest cells, has been difficult to reconstruct. This volume will use a comparative approach to survey the development of the neural crest in vertebrates, and neural crest-like cells, across the metazoa. This information will be used to reveal neural crest evolution and identify the genomic, genetic, and gene-regulatory changes that drove them.

Key selling features:

  • Summarizes the data regarding neural crest cells and nerural crest derivatives
  • Uses a broad-based comparative approach
  • Suggests hypothesis that the origin of neural crest cells involved the novel co-activation of ancient metazoan gene programs in neural border cells
  • Illustrates how the emergences of neural crest made possible the diversification of vertebrate heads
  • Table of Contents


    Chapter 1 Foreword

    Chapter 2 A Vertebrate Invention

    Chapter 3 The Evolution of Cellular EMT and Migration

    Chapter 4 The Evolution of the Neural Border and Peripheral Nervous System

    Chapter 5 The Hunt for Neural Crest in Invertebrate Chordates

    Chapter 6 Elaboration of fates in neural crest lineage during evolution

    Chapter 7 On the evolution of skeletal cells before and after neural crest

    Chapter 8 Neural crest and craniofacial evolution of early vertebrates

    Chapter 9 Neural crest in fossil vertebrates: what, if anything, can we know?

    Chapter 10 Evolving neural crest cells: Hopes for present and future understanding

    About the Editors

    Daniel Meulemans Medeiros is an associate professor at the University of Colorado, Boulder. His lab uses a comparative developmental genetic approach, to better understand the evolutionary origins and diversification of the vertebrate head, a topic Dr. Medeiros has been studying for more than 16 years. Dr. Medeiros has published over 30 original research articles and several literature reviews on vertebrate head skeleton development and evolution, focusing on neural crest-derived skeletal tissues. Dr. Medeiros’ research program has been continuously funded by multiple major grants from the NSF and NIH. Current projects in the Medeiros lab exploit new methods for monitoring and perturbing developmental gene expression in organisms occupying key phylogenetic nodes for understanding vertebrate evolution, including the jawless vertebrate lamprey, the vertebrate-like invertebrate chordate, amphioxus, zebrafish, and the African clawed frog.

    About the Series

    Evolutionary Cell Biology

    Learn more…

    Subject Categories

    BISAC Subject Codes/Headings:
    NATURE / Animals / General
    SCIENCE / Life Sciences / Cytology
    SCIENCE / Life Sciences / Evolution
    SCIENCE / Life Sciences / General