A wide-ranging compilation of techniques, Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals describes methods of extrapolation in the framework of ecological risk assessment. The book, informally known as EXPECT, identifies data needs and situations where these extrapolations can be most usefully applied, making it a practical guide to the application of extrapolation procedures. It focuses on the extrapolation of chemical effects and covers the extrapolation of exposures in the context of interactions between toxicants and the matrix.
Table of Contents
Extrapolation in the Context of Criteria Setting and Risk Assessment. Matrix and Media Extrapolation. (Q)SAR and Extrapolation. Extrapolation of Effects Measures Across Levels of Biological Organization in Ecological Risk Assessment. Mixture Extrapolation Approaches. Temporal Extrapolation en Ecological Effect Assessment of Chemicals. Spatial Extrapolation in ecological Effect Assessment of Chemicals. Guidance on the Application of Extrapolation Methods in Ecological Exposure and Effects Characterization of Chemicals. Conclusions. Glossary.
Solomon, Keith R.; Brock, Theo C.M.; De Zwart, Dick; Dyer, Scott D.; Posthuma, Leo; Richards, Sean; Sanderson, Hans; Sibley, Paul; van den Brink, Paul J.