Food-Drug Synergy and Safety: 1st Edition (Hardback) book cover

Food-Drug Synergy and Safety

1st Edition

Edited by Lilian U. Thompson, Wendy E. Ward

CRC Press

488 pages | 29 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9780849327759
pub: 2005-08-23
SAVE ~$43.00
Currently out of stock
eBook (VitalSource) : 9780429129919
pub: 2005-08-23
from $28.98

FREE Standard Shipping!


Scientists, health professionals, and consumers are increasingly interested in the relationships between food components and food-drug combinations as they strive to find more effective ways to prevent or treat chronic disease. As one of the first unified and in-depth sources in this emerging topic, Food-Drug Synergy and Safety explores the vast potential benefits of food and food-drug synergy.

The book addresses the interaction of two or more components within a single food, between several foods, or between foods and drugs consumed together, in which the potential health benefit is greater than the effect of the single component, food, or drug. Each chapter follows a consistent framework and addresses the health benefits, mechanisms of action, and safety aspects pertaining to the food and food-drug synergies. Sections discuss food and food-drug synergies in the context of specific disease groups, such as cardiovascular disease, cancer, osteoporosis, inflammatory diseases, hypertension, and obesity, for easy reference in a clinical setting. A separate section focuses entirely on performance enhancers, including caffeine, creatine, and ephedrine/ephedra, and their potential to influence human health in addition to ergogenic applications.

The final section provides scientists with a framework for designing experiments that elucidate the heath benefits and safety aspects of food and food-drug synergies. Food-Drug Synergy and Safety lays the essential foundation in this new direction of research as it gains momentum in the fields of food, nutrition, medicine, and pharmaceutical sciences.

Table of Contents

Section I: Introduction

Understanding Food and Food-Drug Synergy; Wendy E. Ward and Lilian U. Thompson

Section II: Cardiovascular Disease

Lipid Sources and Plant Sterols: Effect of Food and Food-Drug Synergy on Cardiovascular Disease Risk; Krista A. Varady and Peter J.H. Jones

Antioxidant Phytochemicals and Potential Synergistic Activities at Reducing Risk of Cardiovascular Disease; David D. Kitts

Synergy of Portfolio Diet Components and Drugs in Coronary Heart Disease; David J.A. Jenkins, Augustine Marchie, Julia M. Wong, Russell de Souza, Azadeh Emam, and Cyril W.C. Kendall

The Role of Complementary Vitamins, Folate, Vitamin B6, and Vitamin B12, in Cardiovascular Disease; Louise Mennen, Pilar Galan, and Angelika de Bree

Food Synergy in Dietary Patterns and Risk for Chronic Diseases; Rob M. van Dam

Section III: Cancer

Soy-Food and Soy-Drug Interactions in Prevention and Treatment of Cancer; Jin-Rong Zhou

Flaxseed, Lignans, n-3 Fatty Acids, and Drug Synergy in the Prevention and Treatment of Cancer; Lilian U. Thompson

Whole-Grain Component Synergy and Cancer; Joanne Slavin

Synergy and Safety of Antioxidants with Cancer Drugs; Kedar N. Prasad

Probiotics: Synergy with Drugs and Carcinogens in Diet; Seppo Salminen, Hani El-Nezami, Eeva Salminen, and Hannu


Section IV: Osteoporosis

Synergy of Soy, Flaxseed, Calcium, and Hormone Replacement Therapy in Osteoporosis; Wendy E. Ward

Synergy of Protein, Fats, and Calcium; Potential Synergies with Drugs for Osteoporosis; Marlena C. Kruger and Raewyn C. Poulsen

Section V: Inflammatory Disease, Hypertension, and Obesity

Molecular Targets for Antiinflammation and Dietary Component-Drug Synergy Akira Murakami and Hajime Ohigashi

Food and Food-Drug Synergies: Role in Hypertension and Renal Disease Protection; Manuel T. Velasquez

Milk Proteins in Food-Food and Food-Drug Synergy on Feeding Behavior, Energy Balance, and Body Weight Regulation; Alfred Aziz and G. Harvey Anderson

Section VI: Ergogenics

Caffeine, Creatine, and Food-Drug Synergy: Ergogenics and Applications to Human Health; Terry E. Graham and Lesley L. Moisey

Section VII: Experimental Designs

Designing Experiments for Food-Drug Synergy: Health Aspects; Lyn M. Steffen

Designing Experiments for Food-Drug Synergy: Safety Aspects; V.J. Feron, J.P. Groten, R.J.J. Hermus, D. Jonker, I. Meijerman, G.J. Mulder, F. Salmon, and E.D. Schoen


Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Nutrition