Forensic DNA Analysis: Technological Development and Innovative Applications provides a fascinating overview of new and innovative technologies and current applications in forensic genetics. Edited by two forensic experts with many years of forensic crime experience with the Italian police and with prestigious academic universities, the volume takes an interdisciplinary perspective, the volume presents an introduction to genome polymorphisms, discusses, forensic genetic markers, presents a variety of new methods and techniques in forensic genetics, and looks at a selection of new technological innovations and inventions now available from commercial vendors.
The book is an important resource for scientists, researchers, and other experts in the field who will find it of interest for its exhaustive discussion of the most important technological innovations in forensic genetics. For those newer to the field, the volume will be an invaluable reference guide to the forensic world.
Table of Contents
Part 1: Introduction to Genome Polymorphisms
1. DNA Polymorphisms and Genome Structure: Different Scales of Variation in the Human Genome
Andrea Novelletto and Bianca Maria Ciminelli
2. Single Nucleotide Polymorphisms: An Overview of the Sequence Polymorphisms
Eugenia D’atanasio, Fulvio Cruciani, and Beniamino Trombetta
Part 2: Forensic Genetic Markers
3. Forensic Identity Markers: An Overview of Forensic Autosomal STRs and SNPs
4. The Y-Chromosomal STRs in Forensic Genetics: Y Chromosome STRs
5. The X-Chromosomal STRs in Forensic Genetics: X Chromosome STRs
Vânia Pereira and Leonor Gusmão
6. Application of Mitochondrial DNA as a Tool in the Forensic Field: Update and New Perspectives in mtDNA Analysis
Manuel Crespillo Márquez, Pedro A. Barrio Caballero, and Carolina Núñez Domingo
Part 3: Novelties in Forensic Genetics
7. Sequencing Technology in Forensic Science: Next Generation Sequencing
Runa Daniel and Sallyann Harbison
8. Forensic Analysis of Externally Visible Characteristics: Phenotyping
Daniele Podini and Katherine B. Gettings
9. Forensic Ancestry Inference: Data Requirements, Analysis Methods, and Interpretation of Results
Oƶlem Bulbul and Kenneth K. Kidd
10. Online Population Data Resources for Forensic SNP Analysis with Massively Parallel Sequencing: An Overview of Online Population Data for Forensic Purposes
C. Phillips et al.
11. Forensic Anthropology Issues: A Synergy Between Physical and Molecular Methods: The Contribution of Degraded DNA Analysis to Physical and Forensic Anthropology
Elena Pilli, Elisa Castoldi, and Cristina Cattaneo
12. The Molecular Autopsy: Complementary Study to Molecular Autopsy
S. Zoppis, A. Blanco-Verea, and M. Brion
13. Wildlife Forensics: DNA Analysis in Wildlife Forensic Investigations
Rita Lorenzini and Luisa Garofalo
14. Forensic Entomology: The Utility of the Insects at Court and in Human Identification
S. Lambiase and A. M. Tarone
Part 4: Company Innovations
15. Getting the Most Information from Every Sample: Improved Length-Based and Sequence-Based Analysis
Rohaizah I. James
16. Paradna® Technology: A Tool for Rapid Identification of DNA and Body Fluids
Laura Dodd, Stephanie Regan, and Tobias Hampshire
17. Deparray™ System: Key Enabling Technology for Cell Separation from Forensic Mixtures
Roberta Aversa et al.
18. Rapid DNA by Ande Corporation: A Useful Tool for Disaster Victim Identification
Rosemary Turingan Witkowski and Richard F. Selden
19. Massively Parallel Sequencing as an Operational Forensic Tool: Current and Future Perspectives: Improving Results for Current Applications and Paving the Way for Expanded Capabilities
Nicola J. Oldroyd Clark and Cydne L. Holt
Elena Pilli, PhD, is a Forensic Molecular Anthropologist and Captain of the Italian Military Police “Carabinieri” at the Forensic Scientific Centre in Rome, Italy, since 2017, a reserve officer selected by CV for her molecular anthropological competence.
Andrea Berti, PhD, is a Forensic Biologist and Lgt. Colonel of the Italian Military Police “Carabinieri” at the Forensic Scientific Centre in Rome, Italy.