This work offers an analysis of the biological processes mediated by free radicals, from a toxicological point of view, providing easy access to information in an integrated, coherent presentation. The chemistry and biochemistry of all principal types of radical are explained, and the multiple forms in whch radicals participate in living organisms are investigated.;This work should be of use to biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists and graduate students in these disciplines.
". . .of great utility to a large group of scientists. . . . . .logically organized. . . . . .very informative. . .Bioinorganic chemists will find the pathology and biomolecule damage sections to be extremely helpful. Toxicologists will benefit from the lucid descriptions of the intimate mechanisms of radical generation. Libraries should certainly make this volume available to students, and many practitioners will want a personal copy. "
---Chemtracts: Biochemistry and Molecular Biology
". . .offers non-specialists an opportunity to follow, step-by-step, the way through the complex domain of radical biology."
Definitions, properties and reactions of radicals; biologically relevant radicals; biomolecular targets for radicals and reactive oxygen species; pathology of radicals and reactive oxygen species; antioxidants and radical scavengers - some therapeutic uses; pharmacology of antioxidant molecules - analysis of their mechanisms of action.