First published in 1993: Fundamentals of Animal Cell Encapsulation and Immobilization is a concise reference volume that consolidates and expands our understanding of animal cell immobilization technology. The book presents fundamental studies that examine polymer toxicity, biocompatibility, mass transfer, and modeling of cell growth and diffusion. Specific applications of encapsulation to Parkinson's Disease are discussed in detail, and droplet generation and scale-up information will benefit researchers attempting to scale-up their cell immobilization systems.
Fundamentals of Animal Cell Encapsulation and Immobilization provides valuable information for industrial and biomedical researchers involved in animal cell immobilization, as well as for materials scientists, biochemists, microbiologists, biologists, and biochemical engineering students who wish to specialize in cell encapsulation.
Table of Contents
1. Cell Immobilization Technology: An Overview
Glenn A. King and Mattheus F.A. Goosen
2. Biomdeical Applications of Immobilized Cells
Lisa Christenson, Keith E. Dionne, and Michael J. Lysaght
3. Toxicity, Biocompatibility, and Mass Transfer Effects in Immobilized Cell Systems
Mattheus F.A. Goosen
4. Control of Membrane Permeability in Microcapsules
Augustine O. Okhamafe and Mattheus F.A. Goosen
5. Mathematical Modeling of Protein Diffusion and Cells Growth in Microcapsules
Pak K. Yuet et al.
6. Scale-up of Gel Bead and Microcapsule Production in Cell Immobilization
Denis Poncelet et al.
7. Development of Polyacrylate Microapsules
William T.K. Stevenson and Michael V. Sefton
8. Living Cells and Microorganisms Immobilized by Microencapsulation inside Artificial Cells
Thomas M.S. Chang
9. Cell Encapsulation for the Nervous System
Patrick Aebischer, Moses Goddard, and Patrick A. Tresco
10. Cultivation of Suspended and Immobilized Insect Cells
Mattheus F.A. Goosen et al.
11. Inverted Microcarriers: Using Microencapsulation to Grow Anchorage-Dependent Cells
Delano V. Young
12. Bioracter Systems Based on Microencapsulated Animal Cell Cultures
Branko Bugarski, Goran Jovanovic, and Gordana Vunjak-Vovakovic
13. Emerging Techniques, Materials, and Applications in Cell Immobilization
Brigitte Poncelet De Smet, Denis Poncelet, and Ronald J. Neufeld
Mattheus F. A. Goosen, Ph.D., is Professor of Chemical Engineering at Queen’s University at Kingston, Ontario.