Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function, knowledge of which is essential to the study of signal transduction.
G Protein-Coupled Receptors has culled contributors from domestic and international sources, providing a broad base of knowledge. Some topics covered are the regulation of receptors; phosphorylation of G-protein-coupled receptors and ion channel receptors; desensitization studies using electrophysiological or confocal microscopic methods and the search for endogenous ligands for orphan receptors.
This volume is useful at both the university and industrial levels, and is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.
Table of Contents
Novel Ligands: Ligand Screening Systems and Orphan Receptors. Function and Regulation: Receptor-G Protein Coupling and Desensitization. 3D Structure: Large-Scale Expression and Electron and X-Ray Crystallography.