This book focuses on human Cytochrome P450s and drug metabolism in Man. It describes the structures of the P450s, and reviews the methodology available to determine their nature, including molecular modelling, X-ray crystallography, spectroscopy, and molecular biology.
Table of Contents
1. Introduction 2. Evolution of the P450 superfamily 3. The P450 catalytic cycle 4. Substrate selectivity and metabolism 5. Regulation of P450 enzymes 6. The structures of cytochromes P450
Lewis, David F.V.; Lewis, David F. V.