HLA Typing: Methodology and Clinical Aspects, 1st Edition (Hardback) book cover

HLA Typing

Methodology and Clinical Aspects, 1st Edition

Edited by Soldano Ferrone, Bjarte G. Solheim

CRC Press

194 pages

Purchasing Options:$ = USD
Hardback: 9780367219154
pub: 2019-08-27
SAVE ~$39.80
eBook (VitalSource) : 9780429268755
pub: 2019-06-04
from $32.50

FREE Standard Shipping!


First published in 1982, this two-volume set provides the reader with insightful knowledge of HLA Typing and the different methods in which this can be undertaken. In this volume, we are presented with inside knowledge of the variety of HLA typing methods and the circumstances in which they are necessary.

Table of Contents

Volume I.

1. Separation Techniques for Mononuclear Blood Cells. 2. The HLA System and Cross-Reactivity. 3. New Aspects of HLA Serology and Biochemistry Defined Using Monoclonal Antibodies. 4. Lysostrip, F(ab’) ₂ Blocking. 5. Screening for HLA Sera. 6. Planned Immunization for the Production of HLA Alloantibodies. 7. Operationally Specific Xenoantisera to Allospecificities of the HLA Antigenic System. 8. Antigenic Constitution of HLA-A, B, C, Molecules: Immunochemical Analysis with Monoclonal Antibodies. 9. Technical Aspects and Clinical Relevance of HLA Typing and the Crossmatch Test in Kidney Transplantation. 10. Separation of B Lymphocytes and HLA-DR Typing. 11. Analysis of Kidney Transplant Outcome in relation to HLA-A, -B Matching. Presentation of a Multicenter Study from Scandinavia. 12. Histocompatibility Matching in Renal Transplantation. 13. HLA and Marrow Transplantation. Index.

Volume II.

1. Complement Fixation Tests in HLA Typing. 2. ADCC in Histocompatibility and Clinical Medicine. 3. HLA Typing of Cells in Long-Term Culture. 4. Granulocyte and Monocyte Antigens and Antibodies. 5. Data Analysis of Cellular Typing. 6. HLA-D Typing by MLC with Homozygous Typing Cells. 7. Primed Lymphocyte Typing (PLT): Application in Typing for HLA-D Locus Determinants. 8. Cell Mediated Lympholysis: A One Step Microplate Technique. 9. The Fluorochromasia Cell Mediated Lympholysis Assay (CML). 10. HLA-A, B Restriction of Cytotoxic T Cells. 11. Histocompatibility Typing by Polyclonal and Cloned Human Cytotoxic T Lymphocytes. 12. Involvement of HLA Cell Membrane Molecules in T Cell Immune Responses: Immunobiological and Clinical Significance. 13. HLA and Disease Associations. Index.

About the Editors

Soldano Ferrone received his M.D. and Ph.D. degrees from the University of Milan, Italy. Currently, he is a Professor in the Department of Pathology, College of Physicians and Surgeons, Columbia University in New York. Prior to his present position, Dr. Ferrone was an Associate Member of Scripps Clinic and Research Foundation, La Jolla, Calif., and Adjunct Professor of Pathology at the University of California at San Diego., Bjarte G. Solheim received his M.D. degree in 1965 from the University of Bergen, Norway, and his Ph.D. degree from the University of Oslo, Norway, in 1972. Currently, he is head of the Blood Typing Laboratory, Rikshospitalet, The National Hospital, in Oslo, Norway.

About the Series

Routledge Revivals

Are there elusive titles that you need and have been trying to source for years but thought that you would never be able to find?

Well this may be the end of your quest – here is a fantastic opportunity for you to discover past brilliance and purchase previously out of print and unavailable titles by some of the world’s most eminent academic scholars.

Drawing from over 100 years of innovative, cutting-edge publishing, Routledge Revivals is an exciting programme whereby key titles from the distinguished and extensive backlist of the many acclaimed imprints associated with Routledge will be re-issued.

The programme draws upon the illustrious backlists of Kegan Paul, Trench & Trubner, Routledge & Kegan Paul, Methuen, Allen & Unwin and Routledge itself.

Routledge Revivals spans the whole of the Humanities and Social Sciences, and includes works by some of the world’s greatest thinkers including Emile Durkheim, Max Weber, Simone Weil, Martin Buber, Karl Jaspers and Max Beloff.

If you are interested in Revivals in the Behavioral Sciences, please visit https://www.routledge.com/series/PSYREVIVALS

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Immunology