This work details current medical uses of antiseptics and disinfectants, particularly in the control of hospital-acquired infections. It presents methods for evaluating products to obtain regulatory approval, and examines chemical, physical and microbiological properties as well as the toxicology of the most widely-used commercial chemicals. Formulations that have broad applications for both medical equipment disinfection and antisepsis are also discussed.
Part 1 Methods: test methodology for evaluation of germicides; a broad-based approach to evaluating topical antiseptics and disinfectants; neutralizer evaluations as control experiments for antimicrobial efficacy studies. Part 2 Application: antiseptics and their role in infection control; disinfectant use in dentistry; contact lens disinfectants and test methods for their evaluation. Part 3 Disinfectants and antiseptics: glutaraldehyde based disinfectants; chlorine and iodine formulations; antimicrobial effects of hydrogen peroxide as an antiseptic and disinfectant; alcohols as antiseptics of hands and skin; chlorohexidine; chloroxylenol (PCMX) - an old-new antimicrobial.