Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.
1. Regulation of Cell Functions 2.Growth Factor Receptors 3.Postreceptor Mechanisms of Growth Factor Action 4.Cyclic Nucleotides 5.Guanosine Triphosphate-Binding Proteins 6.The Calcium-Calmodulin System 7.Phosphoinositide Metabolism 8.Protein Phosphorylation 9.Proto-Oncogene and Onco-Suppressor Gene Expression 10.Role of Growth Factors in Neoplastic Processes. Index.