Biomedical research involving animals remains essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Following in the footsteps of its predecessors, the Handbook of Laboratory Animal Science, Volume II, Third Edition: Animal Models explains in great detail the comparative considerations underlying the choice of animal species and strains in different research disciplines.
Efficient and humane experimental work with animals, in which subjects experience no avoidable pain and mental distress, requires skillful and conscientious staff. To this end, scientists apply the three R’s: replacing experiments on live animals with alternative methods, reducing the number of animals necessary to obtain valid results within experiments, and refining techniques to minimize the discomfort experienced by the animal participants.
Table of Contents
Animal Models, Jann Hau
Animal Models for Human Behavior, Steven J. Schapiro
Animal Models for Psychological Disorders, Robert Murison and Anne Marita Milde
Animal Models in Neuroscience, Jesper Mogensen
Induced Animal Models of Parkinson’s Disease, G. A. Smith, E. Murphy, S. B. Dunnett, and E. L. Lane
Animal Models in Aging and Alzheimer’s Disease, Yael H. Edrey and Rochelle Buffenstein
Animal Models in Pain Research, Klas S. P. Abelson and John V. Roughan
Animal Models in Pharmacology and Toxicology, Otto Meyer, Ove Svendsen, and Jens Lykkesfeldt
Animal Models for Otolaryngological Disorders, Mikhail Wadie and Clarence T. Sasaki
Animal Models of Lung Physiology during Anesthesia, Göran Hedenstierna, Görel Nyman, and Claes Frostell
Animal Models of Female Reproduction and Fetal Growth and Development, Anthony M. Carter
Animal Models in Vaccinology, Coenraad F. M. Hendriksen
Animal Models in AIDS Research, K. Jagannadha Sastry, Pramod N. Nehete, Amy N. Courtney, and Danielle R. Fontenot
Animal Models for the Study of Helicobacter Infection, Akira Nishizono
Animal Models in Mycology, Henrik Elvang Jensen
Animal Models in Biodefense Research, Mark A. Suckow and Patrick Sharp
Animal Models in Oral Health Sciences, Björn Klinge and Jörgen Jönsson
Animal Models of Hearing Loss and Tinnitus, Richard Salvi, Edward Lobarinas, Guang-Di Chen, Daniel Stolzberg, and Dalian Ding
"[A] valuable reference book, and potentially a course book for undergraduate and graduate laboratory animal science courses. … [T]he text is well organized and well referenced. I would highly recommend this book as a reference text for all scientists using traditional laboratory animal species … ."
-- Contemporary Topics in Laboratory Animal Science, Vol. 43, No. 5, Sept. 2004
"Both volumes of this book are well written, user friendly … it fills a current void by collecting together current practices in the scientific use of animals. Each chapter is well referenced and the book would be a valuable addition to the reference collections of animal facilities and research establishments."
-- Bryan Howard, Animal Welfare, 2004
"Hau and Van Hoosier have drawn together information of the highest quality … both volumes of this book will be valuable additions to the shelves of any veterinary surgeon involved in the field, either as a named vet or as a member of the multidisciplinary scientific team required in modern biomedical research."
-- Paul Townsend, The Veterinary Record, May 31, 2003
"The text is quite easy to navigate using the chapter contents and index. The photographs and tables are clear and well used throughout. …The vast scope of information that this handbook contains is diverse, informative, and quite useful. The strength of these volumes is in their ability to cover a broad range of topics yet in such detail. This set would be an asset to the graduate student and researcher needing an excellent reference manual."
-- Sandra L. Jex, Animal Lab News, July/Aug 2003