Handbook of Laboratory Animal Science, Volume III: Animal Models, 3rd Edition (Hardback) book cover

Handbook of Laboratory Animal Science, Volume III

Animal Models, 3rd Edition

Edited by Jann Hau, Steven J. Schapiro

CRC Press

334 pages | 8 Color Illus. | 23 B/W Illus.

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Description

While replacing and reducing the use of laboratory animals are integral parts of the 3Rs—replace, reduce, refine—which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines.

The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models.

This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.

Reviews

Praise for the previous volumes:

"The strength of these volumes is in their ability to cover a broad range of topics, yet in such detail. This set would be an asset to the graduate student and researcher needing an excellent reference manual."

—Sandra L. Jex, Animal Lab News

Table of Contents

Animal Models of Spinal Cord Injury

Michelle A. Hook

Animal Models for Tropical Parasitic Diseases

Idle Farah, Maina Ngotho, John Kagira, Thomas Kariuki, Maamun Jeneby, Naomi Maina, Michael Gicheru, Hastings Ozwara, and Jann Hau

Animal models of cardiovascular disease

Meg Sleeper

Animal Models of Sudden Infant Death Syndrome

Jane Blood-Siegfried

More Animal Models of Developmental Processes and Developmental Disorders for Social Genomics and Beyond

Matthew F. S. X. Novak and Dorothy J. Mandell

Animal Models of Metabolic and Inflammatory Diseases

Axel Kornerup Hansen

Animal Models for Eye Diseases

Takeshi Iwata, Ph.D.

Animal Models of Human Cancer

Lezlee G. Coghlan

Reduction and Refinement Applied to Animal Models

Jann Hau and Steven J. Schapiro

About the Editors

Jann Hau is a professor of comparative medicine at the University of Copenhagen in Denmark. Dr. Hau has published more than 200 peer-reviewed papers in comparative medicine and chapters in books, and he is frequently invited to speak at international conferences and symposia. He is the recipient of prizes awarded for his research and contributions to animal welfare.

Steven J. Schapiro is an associate professor of comparative medicine in the Department of Veterinary Sciences at the Michale E. Keeling Center for Comparative Medicine and Research of the University of Texas M. D. Anderson Cancer Center. He is one of the founding faculty members of the Primate Training and Enrichment Workshops. Dr. Schapiro has published approximately 140 peer-reviewed papers and book chapters examining various aspects of nonhuman primate behavior, management, and research.

Subject Categories

BISAC Subject Codes/Headings:
MED089000
MEDICAL / Veterinary Medicine / General
MED089020
MEDICAL / Veterinary Medicine / Food Animal
MED106000
MEDICAL / Research
SCI086000
SCIENCE / Life Sciences / General
SCI089000
SCIENCE / Life Sciences / Neuroscience