Handbook of Lipid Membranes
Molecular, Functional, and Materials Aspects
- Available for pre-order. Item will ship after August 5, 2021
This handbook provides a comprehensive overview of lipid membrane fundamentals and applications. It gives the fundamental physical and biochemical aspects of membrane-related processes in living cells, and then relates them to how scientists are building bioinspired, artifical membrane-based systems such as gene delivery vehicles and synthetic membrane interfaces. It highlights the driving mechanism behind lipid self-assembly, membrane shape evolution, and vesicle trafficing, as well as the role of lipid membrane composition in signalling and the structural aspects of membranes in cellular integrity.
- Includes a broad overview on the role of lipids as structural components of membranes, energy storage molecules, and signaling molecules.
- Covers lipids in signaling and the role of lipids in everyday life, from diet and health to cosmetics and pharmaceuticals.
- Discusses applications in nanotechnology and biomedicine, including liposomes in drug discovery, lipids for in vivo therapeutics, lipid-based sensors, artificial biointerfaces, and synthetic polymers.
- Includes an exciting section that explores the practical use of Archae lipids, lipids and the origins of life, and future outlook for the field.
This book is a great companion for professionals in physics, biochemistry, physical chemistry and material sciences.
Table of Contents
1. A Short History of Membrane Physics. 2. Structures of Lipid Membranes: Lamellar (Liquid Crystalline) Phases 3. Structures of Lipid Membranes: Cubic and Inverse Hexagonal Phases 4. Structure of lipid membranes by advanced x-ray scattering and imaging. 5. Adhesion Protein Architecture and Intermembrane Potentials: force measurements and biological significance. 6. Charged Membranes: Poisson-Boltzmann theory, DLVO paradigm and beyond. 7. Membrane Shape Evolution In Vitro. 8. Mechanisms of membrane curvature generation by peptides and proteins: A unified perspective on antimicrobial peptides. 9. Lipid Membrane Shape Evolution and the Actin Cytoskeleton. 10. Effects of Osmotic Stress on Topologically Closed Membrane Compartments. 11. Cationic Liposomes as Spatial Organizers of Nucleic Acids in One, Two, and Three Dimensions: Liquid Crystal Phases with Applications in Delivery and Bionanotechnology. 12. Lipids in DNA, RNA, and Peptide Delivery for In Vivo Therapeutic Applications. 13. Electrostatics of Lipid Membranes Interacting with Oppositely Charged Macromolecules. 14. Lipid-based bioanalytical sensors. 15. Lipids in Dermal Applications: Cosmetics and Pharmaceutics. 16. Supported Lipid Bilayers. 17. Artificial membranes composed of synthetic copolypeptides. 18. Synthetic membranes from block co-polymers, recombinant proteins and dendrimers. 19. Amphiphilic self-assembly and the origin of life in hydrothermal conditions.
Cyrus R. Safinya is professor of physics at the University of California, Santa Barbara, USA.
Joachim O. Rädler is professor of experimental physics at Ludwig-Maximilians-Universität München, Germany.