Handbook of Lipid Membranes : Molecular, Functional, and Materials Aspects book cover
1st Edition

Handbook of Lipid Membranes
Molecular, Functional, and Materials Aspects

ISBN 9781466555723
Published September 15, 2021 by CRC Press
376 Pages 100 Color & 61 B/W Illustrations

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Book Description

This handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology.

Key Features:

  • Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions
  • Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution
  • Covers advanced X-ray and force measurement techniques
  • Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces
  • Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins
  • Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions

This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.

Table of Contents




Chapter 1 A Short History of Membrane Physics

Erich Sackmann and Avinoam Ben-Shaul

Chapter 2 Structures and Interactions in Freely Suspended Multilayer Membranes and Dilute Lamellar Fluid Membranes from Synchrotron X-Ray Scattering

Gregory S. Smith and Cyrus R. Safinya

Chapter 3 Structures of Lipid Membranes: Cubic and Inverse Hexagonal Phases

Charlotte E. Conn and John M. Seddon

Chapter 4 Structure of Lipid Membranes by Advanced X-Ray Scattering and Imaging

Tim Salditt

Chapter 5 Adhesion Protein Architecture and Intermembrane Potentials: Force Measurements and Biological Significance

Deborah E. Leckband

Chapter 6 Charged Membranes: Poisson・Boltzmann Theory, the DLVO Paradigm, and Beyond

Tomer Markovich, David Andelman, and Rudolf Podgornik

Chapter 7 Membrane Shape Evolution In Vitro

Alexandra Zidovska

Chapter 8 Mechanisms of Membrane Curvature Generation by Peptides and Proteins: A Unified Perspective on Antimicrobial Peptides

Michelle W. Lee, Nathan W. Schmidt, and Gerard C. L. Wong

Chapter 9 Lipid Membrane Shape Evolution and the Actin Cytoskeleton

David R. Slochower, Yu-Hsiu Wang, Ravi Radhakrishnan, and Paul A. Janmey

Chapter 10 Effects of Osmotic Stress on Topologically Closed Membrane Compartments

James C. S. Ho, Bo Liedberg, and Atul N. Parikh

Chapter 11 Cationic Liposomes as Spatial Organizers of Nucleic Acids in One, Two, and Three Dimensions: Liquid Crystal Phases with Applications in Delivery and Bionanotechnology

Cyrus R. Safinya, Kai K. Ewert, Youli Li, and Joachim O. Rädler

Chapter 12 Lipids in DNA, RNA, and Peptide Delivery for In Vivo Therapeutic Applications

Tyler Goodwin and Leaf Huang

Chapter 13 Electrostatics of Lipid Membranes Interacting with Oppositely Charged Macromolecules

Guilherme Volpe Bossa, Klemen Bohinc, and Sylvio May

Chapter 14 Lipid-Based Bioanalytical Sensors

Marta Bally, Hudson Pace, and Fredrik Hook

Chapter 15 Lipids in Dermal Applications: Cosmetics and Pharmaceutics

Jerome Bibette and Abdou Rachid Thiam

Chapter 16 Supported Lipid Bilayers

Theo Lohmuller, Bert Nickel, and Joachim O. Rädler

Chapter 17 Artificial Membranes Composed of Synthetic Copolypeptides

Timothy J. Deming

Chapter 18 Synthetic Membranes from Block Copolymers, Recombinant Proteins, and Dendrimers

Daniel A. Hammer, Zhichun Wang, Ellen Reed, Chen Gao, and Kevin B. Vargo

Chapter 19 Amphiphilic Self-Assembly and the Origin of Life in Hydrothermal Conditions

Christos D. Georgiou and David W. Deamer


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Cyrus R. Safinya is professor of physics at the University of California, Santa Barbara, USA.

Joachim O. Rädler is professor of experimental physics at Ludwig-Maximilians-Universität München, Germany.