Handbook of Obesity -- Volume 1 : Epidemiology, Etiology, and Physiopathology, Third Edition book cover
3rd Edition

Handbook of Obesity -- Volume 1
Epidemiology, Etiology, and Physiopathology, Third Edition

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ISBN 9781842145562
Published March 6, 2014 by CRC Press
736 Pages

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Book Description

In recent years, we’ve developed a much better grasp of the biological and other factors associated with the development of obesity. Reflecting our evolving understanding of causes and consequences, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology provides comprehensive coverage of the biological, behavioral, and environmental determinants of this critical condition. This new edition is divided into five sections exploring essential factors involved in obesity research:

  • History, Definitions, and Prevalence: Changes over time surrounding our notion of obesity, adiposity traits, and the epidemiology of obesity in various populations
  • Biological Determinants of Obesity: Genetic and epigenetic evidence, fetal life and postnatal influences, the use of animal models in research, endocrine issues, molecular aspects, and issues related to viral infection and adiposity
  • Behavioral Determinants of Obesity: The effects of food and ingestive behavior, smoking, breastfeeding, sleep duration, work/leisure time activity, and sedentary behavior
  • Environmental, Social, and Cultural Determinants of Obesity: The role of agriculture and the food industry, the urban environment, social and economic aspects, cultural factors, environmental pollutants, and economic costs
  • Consequences of Obesity: How excess weight affects and exacerbates a range of comorbid conditions, including diabetes, cardiovascular disease, pulmonary disorders, arthritis, and cancer

This volume assembles the work of worldwide experts to deliver an up-to-date survey of the most essential information related to the causes of the obesity epidemic.

Table of Contents

History, Definitions, and Prevalence
Obesity Has Always Been with Us: An Historical Introduction; George A. Bray
Measurement of Total Adiposity, Regional Fat Depots, and Ectopic Fat; Steven B. Heymsfield, Houchun Harry Hu, ZiMian Wang, Wei Shen, and Ye Jin
Anthropometric Indicators in Relation to the Gold Standards; Peter T. Katzmarzyk
Worldwide Prevalence of Obesity in Adults; Jacob C. Seidell
Prevalence and Consequences of Pediatric Obesity; Nazrat M. Mirza and Jack A. Yanovski
Obesity in Older Adults in the United States; Tala H.I. Fakhouri, Brian K. Kit, Margaret D. Carroll, Katherine M. Flegal, and Cynthia L. Ogden
Gender, Ethnic, and Geographic Variation in Adiposity; Timothy Olds and Carol Maher
Biological Determinants of Obesity
Genetic Component to Obesity: Evidence from Genetic Epidemiology; Louis Pérusse, Treva K. Rice, and Claude Bouchard
Genes and the Predisposition to Obesity; Marcel den Hoed and Ruth J. F. Loos
Epigenetic Mechanisms in Obesity; Robert A. Waterland
Fetal and Early Postnatal Life Determinants of Adiposity; Felicia M. Low, Peter D. Gluckman, and Mark A. Hanson
Animal Models of Obesity: Perspectives on Evolution of Strategies for Their Development and Analysis of Their Phenotypes; Heike Münzberg, Tara M. Henagan, and Thomas W. Gettys
Animal Models of Obesity: Nonhuman Primates; Barbara C. Hansen
CNS Regulation of Energy Balance; Hans-Rudolf Berthoud and Barry E. Levin
Gastrointestinal Regulation of Energy Balance; Timo D. Müller, Kristy Heppner, Chun-Xia Yi, Paul T. Pfluger, and Matthias H. Tschöp
Gut Microbiome and Obesity; Patrice D. Cani
Sympathetic Nervous System and Endocrine Determinants of Energy Balance; Hamid R. Farshchi and Ian A. Macdonald
Insulin Resistance and Obesity; Charmaine S. Tam, Morvarid Kabir, Richard N. Bergman, and Eric Ravussin
White and Brown Adipose Tissue Development; Meghan E. McDonald and Stephen R. Farmer
Adipose Tissue Metabolism, Adipokines, and Obesity; Dominique Langin and Max Lafontan
Visceral Adipose Tissue and Ectopic Fat Deposition; Amalia Gastaldelli
Skeletal Muscle Metabolism and Obesity; Jeffrey J. Brault, G. Lynis Dohm, and Joseph A. Houmard
Mitochondrial Bioenergetic Aspects of Obesity and Weight Loss; Mary-Ellen Harper, Robert Dent, and Ruth McPherson
Resting Metabolic Rate, Thermic Effect of Food, and Obesity; Yves Schutz and Abdul G. Dulloo
Energy Cost of Exercise, Postexercise Metabolic Rates, and Obesity; Einat Shalev-Goldman, Trevor O’Neill, and Robert Ross
Energy Partitioning, Substrate Oxidation Rates, and Obesity; Angelo Tremblay, Yves Deshaies, and Katherine Cianflone
Viral Infections and Adiposity; Nikhil V. Dhurandhar, Emily J. Dhurandhar, and Richard L. Atkinson
Behavioral Determinants of Obesity
Obesity: Influence of the Food Environment on Ingestive Behaviors; Richard D. Mattes and Sze Yen Tan
Obesity and Related Eating Disorders; Brooke A. Bailer, Lauren E. Bradley, and Kelly C. Allison
Tobacco Use, Smoking Cessation, and Obesity; Carole Clair, Semira Gonseth, Jacques Cornuz, and Ivan Berlin
Breastfeeding and Later Obesity; Nancy F. Butte
Beverages and Obesity: Biology, History, Trends; Barry M. Popkin and Frank B. Hu
Sedentary Time and Obesity; Neville Owen and Marc Hamilton
Occupational Work and Obesity; Nicholas D. Gilson and Catrine Tudor-Locke
Leisure-Time Physical Activity and Obesity; Thrudur Gunnarsdottir, Renee J. Rogers, John M. Jakicic, and James O. Hill
Sustained Short Sleep and Risk of Obesity: Evidence in Children and Adults; Michelle A. Miller, George Smith, Andrew O’Keeffe, and Francesco P. Cappuccio
Environmental, Social, and Cultural Determinants of Obesity
Role of Agriculture and the Food Industry in America’s Obesity; James E. Tillotson
Transportation Policies and Obesity; David R. Bassett Jr.
Urban Environment, Building Design, and Obesity; Reid Ewing and Gail Meakins
Social and Economic Determinants of Obesity; Lindsay McLaren
Influence of Culture on Obesity; Alison Tovar and Aviva Must
Bias, Discrimination, and Obesity; Rebecca M. Puhl, Kelly D. Brownell, and Jenny A. DePierre Environmental Chemicals and Obesity; Amanda S. Janesick, Thaddeus T. Schug, Jerrold J. Heindel, and Bruce Blumberg
Economic Costs of Obesity; Ping Zhang, Sundar S. Shrestha, and Rui Li
Consequences of Obesity
Obesity and Mortality Rates; Gary Whitlock and Rachel R. Huxley
Obesity and Heart Disease; Peter W.F. Wilson
Obesity and Hypertension; Raj S. Padwal and Arya M. Sharma
Obesity and Lipoprotein Metabolism; Sally Chiu and Ronald M. Krauss
Obesity and Type Diabetes; Henna Cederberg and Markku Laakso
Obesity and Metabolic Syndrome; Jean-Pierre Després
Obesity and Cancer: Clinical Epidemiology; Andrew G. Renehan
Inflammatory Causes of Obesity and Metabolic Diseases; Ebru Erbay and Gökhan S. Hotamıs¸lıgil
Obesity and Gallbladder Disease; Cynthia W. Ko and Sum P. Lee
Obesity and Liver: Cell Death, Compensatory Growth, and Repair of Damage; Giovanni Tarantino
Obesity, Lung Function, and Lung Disease; Nour A. Assad, Jesse H. Alvarado, and Akshay Sood
Obesity, Arthritis, and Gout; Luke Dawson, Anita E. Wluka, Yuanyuan Wang, and Flavia M. Cicuttini
Obesity and Mental Health; Lucy F. Faulconbridge and Anthony Fabricatore
Obesity and Health-Related Quality of Life; Donald A. Williamson and W. Jack Rejeski
Obesity and Pregnancy Outcomes; Raul Artal and Sarah Hopkins
Obesity, an Inactive Lifestyle and Low Fitness: The Most Unhealthy Combination; Paul A. McAuley and Steven N. Blair

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George A. Bray, MD, MACP, MACE, is a former executive director and current Boyd Professor at Pennington Biomedical Research Center of the Louisiana State University System in Baton Rouge, Louisiana. He is also a professor of medicine at the Louisiana State University Medical Center in New Orleans, an adjunct professor of physiology in the School of Veterinary Medicine, and an adjunct professor of food science in the College of Agriculture at Louisiana State University. His research focuses on physiological mechanisms for obesity and the evaluation of treatment for obesity and diabetes.

Claude Bouchard, PhD, is a former executive director and current John W. Barton, Sr. Endowed Chair in Genetics and Nutrition at the Pennington Biomedical Research Center of the Louisiana State University System in Baton Rouge, Louisiana. His research focuses on the genetics of obesity and its comorbidities, as well as on the genetics of adaptation to regular exercise in terms of cardiovascular and diabetes risk factors.


"This two-volume set of books is the most comprehensive encyclopaedia of obesity that I have read … Name any aspect of obesity and this book has it covered! Reading it from beginning to end is a pleasurable education, whilst digital access via VitalBook (eBook) on your VitalSource Bookshelf (included in the price) will enable immediate offline access in the clinic or seminar…The book is the product of a huge international college of contributors whose presentations are ably and intuitively orchestrated by the editors. As a comprehensive treatise on all aspects of obesity I cannot recommend it enough."
—Jim Young, Editor-in-Chief, Glycosmedia