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Handbook of Pharmaceutical Biotechnology




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ISBN 9780789001528
Published April 2, 2003 by CRC Press

 
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Book Description

Stay up to date with changes in the biopharmaceutical products market!

With the growth rate of biopharmaceutical products ascending rapidly since the 1980s, the number of biotechnology companies has risen to more than 1200 new businesses in the Unites States alone. This dramatic increase creates a new set of challenges in education, putting demands on teachers and students to keep pace with innovations in terminology and techniques. The Handbook of Pharmaceutical Biotechnology is essential in meeting those challenges.

A practical compendium of biotechnology-produced drugs, the Handbook of Pharmaceutical Biotechnology covers general principles of biotechnology and pharmaceuticals, putting usable information in the hands of those who need it most. The book presents descriptions that break down each pharmaceutical product by pharmacology, pharmacokinetics, clinical applications, toxicities, and dosage guidelines. It also reviews prescription products, discussing clinical uses and trials, adverse reactions, and more. Tables, figures, and extensive references add to each comprehensive summary.

The Handbook of Pharmaceutical Biotechnology also includes up-to-date information on:

  • monoclonal antibodies (Abciximab, Muromonab-CD3)
  • enzymes and regulators of enzyme activity (Alteplase, clotting factors, Dornase alpha)
  • anticytokines
  • olgonucleotide and gene therapy
  • hematopoietic growth factors (interleukins, interferons, colony stimulating factors, erythropoietin)
As the worldwide production and sales of biotechnology-derived pharmaceuticals and diagnostics continues to grow, teachers, students, and clinical pharmacists need to maintain a clear and current understanding of the field. The Handbook of Pharmaceutical Biotechnology presents a thoughtful and thorough guide to keeping pace in this evolving industry.

Table of Contents

  • About the Editors
  • Contributors
  • Chapter 1. Introduction to Biotechnology
  • Delivery of Recombinant DNA into Expression Vectors
  • Host or Expression Cells
  • Development of Recombinant Protein
  • Hybridoma Technology
  • Chimerization Process
  • Chapter 2. Monoclonal Antibodies
  • Introduction
  • Abciximab (Reopro®)
  • Muromonab-CD3 (Orthoclone®)
  • Basiliximab (Simulect®)
  • Daclizumab (Zenapax®)
  • Rituximab (Rituxan®)
  • Trastuzumab (Herceptin®)
  • Palivizumab (Synagis®)
  • Chapter 3. Clotting Factors
  • Introduction
  • Recombinant Factor VIII (NovoSeven®)
  • Factor VIII
  • Antihemophilic Factor (Recombinant) (Recombinate™)
  • Antihemophilic Factor (Recombinant) (Kogenate®)
  • Recombinant, B-Domain Deleted Factor VIII, r-FVIII SQ (Refacto®)
  • Factor IX rFIX (Benefix®)
  • Chapter 4. Enzymes and Regulators of Enzyme Activity
  • Introduction
  • Alteplase (Activase®)
  • Reteplase (Retavase®)
  • Lanoteplase
  • Tenecteplase
  • Dornase Alfa (Pulmozyme®)
  • Chapter 5. Cytokines (Stan G. Louie and Parul Patel)
  • Introduction
  • Interleukin 2
  • Interleukin-11
  • Interferons
  • Colony-Stimulating Factors
  • Platelet-Derived Growth Factor BB
  • Chapter 6. Anticytokines
  • Introduction
  • Interleukin-1 Receptor Antagonist
  • Tumor Necrosis Factor Soluble Receptor
  • TNF- Soluble Receptor p55-IgG1 Fusion Protein
  • Chapter 7. Oligonucleotide and Gene Therapy
  • Introduction
  • Oligonucleotide Therapy
  • ras-Antisense Therapy
  • Gene Delivery Systems
  • Current Strategies for Cancer Gene Therapy
  • Clinical Trials with Gene Therapy
  • Conclusion
  • Index
  • Reference Notes Included

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