First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time.
1. Pharmacokinetic-Pharmacodynamic Modeling of Reversible Drug Effects
2. Pharmacokinetic-Pharmacodynamic Modeling of Irreversible Drug Effects
3. Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications
J. Fleishaker and J. Ferry
4. Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling
G. Hochhaus and H. Derendorf
5. Pharmacokinetic-Pharmacodynamic Correlations of Anesthetics Agents
V.D. Schmith and K. Muir
6. Pharmacokinetic-Pharmacodynamic Correlations of Analgesics
7. Pharmacokinetic-Pharmacodynamic Correlations of Benzodiazepines
8. Pharmacokinetic-Pharmacodynamic Correlations of Anticonvulsants
M. Danhof and R. Voskuyl
9. Pharmacokinetic-Pharmacodynamic Correlations of Cardiovascular Drugs
10. Pharmacokinetic-Pharmacodynamic Correlations of Selected Vasodilators
T.-B. Tzeng and H.-L. Fung
11. Pharmacodynamics Correlations of Anticoagulants
D. Mungall and R.H. White
12. Pharmacokinetic-Pharmacodynamic Correlations of Antihistamines
E. Snoeck, A. Van Peer, and J. Heykants
13. B2-Agonists: Terbutaline, Albuterol, and Fenoterol
G. Hochhaus and H. Mllmann
14. Pharmacokinetic-Pharmacodynamic Correlations of Corticosteriods
H. Mllmann et al.
15. Pharmacokinetic-Pharmacodynamic Modeling of Antibiotics
A.Nolting and H. Derendorf
16. Clinical Pharmacodynamics of Anticancer Drugs
H.L. McLeod and W.E. Evans
17. Computer Applications in Clinical Pharmacokinetics and Pharmacodynamics
D. Mungall, J. Heissler, and M. Kaltenbach
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