1st Edition

Handbook of Pharmacokinetic/Pharmacodynamic Correlation

ISBN 9780367228033
Published June 12, 2019 by CRC Press
483 Pages

USD $200.00

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Book Description

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time.

Table of Contents

1. Pharmacokinetic-Pharmacodynamic Modeling of Reversible Drug Effects

J. Venitz

2. Pharmacokinetic-Pharmacodynamic Modeling of Irreversible Drug Effects

S. Ebert

3. Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications

J. Fleishaker and J. Ferry

4. Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling

G. Hochhaus and H. Derendorf

5. Pharmacokinetic-Pharmacodynamic Correlations of Anesthetics Agents

V.D. Schmith and K. Muir

6. Pharmacokinetic-Pharmacodynamic Correlations of Analgesics

J.S. Walker

7. Pharmacokinetic-Pharmacodynamic Correlations of Benzodiazepines

S.K. Gupta

8. Pharmacokinetic-Pharmacodynamic Correlations of Anticonvulsants

M. Danhof and R. Voskuyl

9. Pharmacokinetic-Pharmacodynamic Correlations of Cardiovascular Drugs

R. Lalonde

10. Pharmacokinetic-Pharmacodynamic Correlations of Selected Vasodilators

T.-B. Tzeng and H.-L. Fung

11. Pharmacodynamics Correlations of Anticoagulants

D. Mungall and R.H. White

12. Pharmacokinetic-Pharmacodynamic Correlations of Antihistamines

E. Snoeck, A. Van Peer, and J. Heykants

13. B2-Agonists: Terbutaline, Albuterol, and Fenoterol

G. Hochhaus and H. Mllmann

14. Pharmacokinetic-Pharmacodynamic Correlations of Corticosteriods

H. Mllmann et al.

15. Pharmacokinetic-Pharmacodynamic Modeling of Antibiotics

A.Nolting and H. Derendorf

16. Clinical Pharmacodynamics of Anticancer Drugs

H.L. McLeod and W.E. Evans

17. Computer Applications in Clinical Pharmacokinetics and Pharmacodynamics

D. Mungall, J. Heissler, and M. Kaltenbach

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Hartmut Derendorf, Ph.D., is Professor and Chairman of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.

Gunther Hochhaus, Ph.D., is Associate Professor of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.