Handbook of Psychiatric Genetics: 1st Edition (Hardback) book cover

Handbook of Psychiatric Genetics

1st Edition

By Kenneth Blum, Ernest P. Noble

CRC Press

512 pages

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Hardback: 9780849344862
pub: 1996-10-29
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Psychiatric genetics is an exciting new discipline that explores how our minds and behavior are influenced by our genes. Increased interest in this area of medical genetics has been sparked by advances in molecular genetic techniques, the genome project, the neurosciences, the role of genes in somatic diseases, and the linking of specific genes with complex mental disorders. This Handbook is the definitive resource on this complex, and sometimes controversial, new field.


"…the authors of the Handbook of Psychiatric Genetics are to be congratulated."

--Wilfrid Noel Raby, M.D., Ph.D., The Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 10, No. 2

Table of Contents

Section I: Genetic Mechanisms in Psychiatry: Analytic Approaches

Association Vs. Linkage Analysis in Mental Disorders, E.M. Wijsman

Genetic Association Studies in Psychiatry: Recent History, J. Gelertner

The Value of Narrow Psychiatric Phenotypes "Super" Normal Controls, S. Hill and K. Neiswander

Section II: DNA Analysis

Isolation of Coding Sequences from the Human Genome: Implication for Neurological Functions and Diseases, P. Jagadeeswaran, M.W. Odom, and Y.C. Liu

Identification of Microsatellite Repeat Markers and Transcribed Sequences in Cloned Genomic DNA, S.R. Pantanjali , R.P. Kandpal, H. Xu, and S.M. Weissman

Section III: Molecular Biology of Receptors and Associated Proteins

Molecular Biology of Opiod Receptors and Associated Proteins, L.N. Wei and H.H. Loh

Phenotypic Analysis of Receptor Genes: Role of Muscarinic Receptor Genes in Neuropsychiatric Disease, M. Braun and Y. Kimura

Studies on Dopamine Receptors and Role in Drug Addiction, G.Y. Ng, S.R. George, and B.F. O'Dowd

Serotonergic Receptors: Role in Psychiatry, J.M. Scalzitti and J.G. Hensler

Brain Adernergic Receptors, D.A. Morilak

Emerging Bacterial Models for GABA Receptors and Transporters, S.C. King

Section IV: Psychiatric Genetics

Identification of Phenotypes for Molecular Genetic Studies of Common Childhood Psychopathology, J. Hudziak

Molecular Genetics of Alzheimer's Disease, G.D. Schellenberg

Polygenic Inheritance in Psychiatric Disorders, D.E. Comings

Molecular Linkage Studies of Manic-Depressive Illness, W. Berrettini

The Genetics of Personality, T.J. Bouchard, Jr.

Family-Based Association of Attention Deficit/Hyperactivity Disorder and the Dopamine Transporter, E.H. Cook, Jr., M.A. Stein, and B.L. Leventhal

Reward Deficiency Syndrome: Neurobiological and Genetic Aspects, K. Blum, J.G. Cull, E.R. Braverman, T.H.J. Chen, and D.E. Comings

Section V: Substance Use Disorders

Polymorphisms of the D2 Dopamine Receptor Gene in Alcoholism, Cocaine and Nicotine Dependence, and Obesity, E.P. Noble

Polymorphisms of the D2 Receptor Gene in Polysubstance Abusers, A.M. Persico and G. Uhl

Association Vs. Linkage Analysis in Compulsive Disorder, A. Parisian, R.D. Todd, and C.R. Cloninger

Association of the A1 and B1 Alleles of the Dopamine D2 Receptor Gene in Severe Japanese Alcoholics, T. Arinami, M. Otokawa, T. Komiyama, H. Mitsushio, H. Mori, H. Mifune, and M. Toru

Behavior Genetic Investigations of Cigarette Smoking and Related Issues in Twins, G.E. Swann and D. Carmeli

The Dopamine D2 Receptor Gene Locus in Reward Deficiency Analysis: Meta-Analyses, K. Blum, P.J. Sheridan, T.J.H. Chen, R.C. Wood, E.R. Braverman, J.G. Cull, and D.E. Comings

Section VI: From Animal Research to Society: Genetic Impact on Behavior

Mapping Quantitative Trait Loci for Behavioral Traits in the Mouse, J.K. Belknap, C. Dubay, J.C. Crabbe, and K.J. Buck

Drug Discrimination: A Tool to Unravel the Genetic Determinants of Alcohol Preference and Aversion, G. Colombo, R. Agabio, C. Lobina, R. Reali, F. Fadda, and G.L. Gessa

Ethical Issues: Genetic Screening, Gene Therapy, and Scientific Conduct, L.S. Parker and E. Gettig


Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Psychiatry / General
MEDICAL / Genetics
SCIENCE / Life Sciences / Neuroscience