Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health, 1st Edition (Hardback) book cover

Herbal Medicines

Development and Validation of Plant-derived Medicines for Human Health, 1st Edition

Edited by Giacinto Bagetta, Marco Cosentino, Marie Tiziana Corasaniti, Shinobu Sakurada

CRC Press

519 pages | 39 B/W Illus.

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pub: 2011-09-28
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The deregulation of dietary supplements and natural products marketing by the FDA has widened the natural products market in Europe and worldwide. While the discussion about the validity of the plant approach to nutrition and diseases treatment continues, the explosion of the use of whatever is considered "natural" has generated concern about effectiveness and danger.

Incorporating information ranging from regulatory aspects to clinical trial and vigilance, Herbal Medicines: Development and Validation of Plant-Derived Medicines for Human Health:

  • Provides a reference model for those who would like to start the R&D process for a natural product
  • Discusses fundamental issues in the development of traditional medicines for the benefit of human health
  • Takes a sequential rational approach to the subject matter
  • Brings awareness to the many problems facing the development of medicinal herbal products, such as quality control, pharmacokinetic, and pharmacodynamic issues

This book takes readers on a rational path for development of efficacious medicinal herbal products. It points out the many problems facing the development of these products, such as quality control, pharmacokinetic, and pharmacodynamic issues. It suggests areas where future developments should occur given healthcare needs and public health considerations.

Table of Contents

The European Legislation (Directive 2004/24/EC) Brings Clarification and Recognition to Herbal Medicinal Products, Giuseppe Nisticò and Dagmar Roth-Behrendt

Taxonomy, Morphology, and Ecology of Medicinal Plants: A Botanical Perspective, Simon Pierce, Alessandra Luzzaro, and Bruno E. L. Cerabolini

Ethnopharmacological Approaches Used to IdentifyMedicinal Plants, Tsukasa Sakurada, Hirokazu Mizoguchi, Soh Katsuyama,Takaakai Komatsu, Hikari Kuwahata, Laura Rombolá, Giacinto Bagetta, Maria Tiziana Corasaniti, and Shinobu Sakurada

Medicinal Plants: Molecular Biology/Biotechnology Approach, Candida Vannini, Manuela Campa, Federica Sassi, and Marcella Bracale

Breeding and Cultivation of Medicinal Plants, Christoph Carlen

Sample Preparation, Analytical Methods and Chemical Standardization of Medicinal Plant, Angela Perrone, Sonia Piacente, Luca Rastrelli, and Giovanni Dugo

The Role of Zebrafish in the Future of Natural Product Discovery, Alexander D. Crawford, Camila V. Esguerra, and Peter A. M. de Witte

Phytocomplexes versus Single-Entity Drugs: The Never-Ending Dilemma in Herbal Medicine, Elizabeth M. Williamson

Molecular Modes of Action of Drugs Used in Phytomedicine, Michael Wink

Bioavailability Issues of Nonnutrient Plant and Fruit Constituents, Mariusz Konrad Piskula and Junji Terao

From Identification to Clinical Translation of Medicinal Plants, Gian Franco Gensini, Luigi Gori, Alfredo Vannacci, and Fabio Firenzuoli

Recommendations for Reporting Randomized Controlled Trials of Herbal Medicine Interventions, Joel J. Gagnier, Heather Boon, Paula Rochon, David Moher, Joanne Barnes, and Claire Bombardier

Pharmacovigilance Methods and Systems in Herbal Medicines, Gioacchino Calapai

Mechanisms and Clinical Relevance of Herb–Drug Interactions from the Perspectives of Pharmacokinetics, Laura Berliocchi, Rossella Russo, Hirokazu Mitsoguchi, and Maria Tiziana Corasaniti

Nature’s Gift to Photodynamic Medicine: Hypericin, a Herbal Photosensitizer, is a Component of Hypericum Perforatum, Heinrich Walt

Plants and Plant-Derived Products as Cancer Chemopreventive Agents, Douglas M. Noonan, Ilaria Sogno, and Adriana Albini

From Standard Tanacetum Parthenium Extract to a Stabilized Derivative of Parthenolide: Studies in Animal Models of Pain, Rosaria Greco, Cristina Tassorelli, Antonina Stefania Mangione, Paolo Morazzoni, Ezio Bombardelli, and Giuseppe Nappi

Antiviral Effects of Essential Oils Used Traditionally in Phytomedicine

Jürgen Reichling and Paul Schnitzler

The Neuroprotective Capacity of Achyrocline Satureioides (Lam) D.C. and its Flavonoids: Mechanisms of Action, Federico Dajas, Juan A. Abin-Carriquiry, Florencia Arredondo, Fernanda Blasina, Marcela Diaz, Carolina Echeverry, Felicia Rivera-Megret, and Lucia Vaamonde

Recent Progress in Echinacea Research, Karin Woelkart and Rudolf Bauer

Contribution of Herbal Medicine to Human Health: A Brief History, Luigi Antonio Morrone, Laura Rombolà, Diana Amantea, Hirokazu Mizoguchi, and Maria Tiziana Corasaniti

Quality Issues of Current Herbal Medicines, Paola Montoro, Sonia Piacente, and Cosimo Pizza

Herbal Medicines in the Developing World: South America, Federico Dajas and Felicia Rivera-Megret

Herbal Medicines: Epidemiology of their Utilization—A Perspective on the Industrialized World, Anna Loraschi and Marco Cosentino


About the Series

Clinical Pharmacognosy Series

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Subject Categories

BISAC Subject Codes/Headings:
HEALTH & FITNESS / Herbal Medications
SCIENCE / Chemistry / General