Heterogeneous Catalysis : A Versatile Tool for the Synthesis of Bioactive Heterocycles book cover
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Heterogeneous Catalysis
A Versatile Tool for the Synthesis of Bioactive Heterocycles




ISBN 9781466594821
Published September 13, 2014 by CRC Press
355 Pages 534 B/W Illustrations

 
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Book Description

For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest.

Topics include:

  • Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalysts
  • Recent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocycles
  • Features of silica-based heterogeneous catalysts, such as abundance, ease of use, and stability
  • Ultrasound as an effective tool for accelerating reactions
  • Organic transformations catalyzed by nano-ZnO as a valuable heterogeneous catalyst
  • Heterogeneous catalysts employed in the synthesis of coumarins
  • Heterocyclizations in the presence of silver salts
  • Home-made organometallic silica sources, known as silatranes

 

Reflecting the focused studies currently conducted in these areas, the book also examines anticancer, antifungal, antibacterial, anti-HIV, anti-inflammatory, antioxidant, and many more biological activities of heterocyclic compounds. It is essential reading for postgraduate and research scholars in the fields of biochemistry, chemical biology, medicinal chemistry and pharmaceutical chemistry.

Table of Contents

Synthesis of Bioactive Heterocyclic Systems Promoted by Silica-Supported Catalysts; Daniela Lanari and Ornelio Rosati
Eco-Benign Synthesis of Indole Derivatives Employing Diverse Heterogeneous Catalysts; Renuka Jain, Kanti Sharma, and Deepak Kumar
Solid Heterogeneous Catalysts Based on Sulfuric Acid and Transition-Metal Salts: Synthesis of Bioactive Heterocycles; Bahador Karami
Heterogeneous Copper-Catalyzed Synthesis of Bioactive Heterocycles; Xin Lv and Guodong Yuan
Silica Sulfuric Acid: A Simple and Powerful Heterogeneous Catalyst in Organic Synthesis; Sushma S. Kauthale, Sunil U. Tekale, Ambadas B. Rode, Sandeep V. Shinde, K. L. Ameta, and Rajendra P. Pawar
Application of Silica-Based Heterogeneous Catalysis for the Synthesis of Bioactive Heterocycles; Laishram Ronibala Devi and Okram Mukherjee Singh
Application of Organometallic Compounds as Heterogeneous Catalysts in Organic Synthesis; Prachi Rathi, Sudesh Kumar, K. L. Ameta, and Dharma Kishore
Ultrasound: An Efficient Tool for the Synthesis of Bioactive Heterocycles; Essam M. Hussein
Nano–Zinc Oxide: An Efficient Heterogeneous Catalyst for the Synthesis of Heterocyclic Compounds; Sunil U. Tekale, Ambadas B. Rode, K. L. Ameta, and Rajendra P. Pawar
Application of Heterogeneous Catalysts for the Synthesis of Bioactive Coumarins; Lokesh A. Shastri and Manohar V. Kulkarni
Silver: A Versatile Heterogeneous Catalyst for Heterocyclic Synthesis; Chetna Ameta and K. L. Ameta
Mesoporous Materials from Novel Silica Source as Heterogeneous Catalyst; Sujitra Wongkasemjit and Rujirat Longloilert

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Author(s)

Biography

K. L. Ameta received his doctorate degree in organic chemistry from M. L. Sukhadia University, Udaipur, India. He is assistant professor of chemistry in the Faculty of Arts, Science and Commerce, Mody Institute of Technology and Science, Deemed University, Lakshmangarh, Rajasthan, India. His research area is the synthesis, characterization, and biological evaluation of bioactive heterocyclic systems of different sizes. In addition, he has keen interest in heterogeneous catalyzed organic synthesis and photocatalysis. He has published a number of research articles in various journals of national and international repute.

Andrea Penoni is assistant professor in organic chemistry at the Department of Science and High Technology at the University of Insubria, Italy. He received a PhD from the University of Milan. He did his postdoctoral training at the University of Milan, and at the University of Oklahoma, where he studied annulation reactions between nitro- and nitrosoaromatics with alkynes. Since 2003, he has been a faculty member at the University of Insubria (Como). His research is particularly focused on the synthesis of heterocycles, naturally occurring compounds, and potentially bioactive molecules. He is also involved in research projects on the carbon–nitrogen bond formation mediated by metals and metal complexes and in the synthesis of nitrogen-containing heterocycles by metathesis reactions.