Image-Guided Hypofractionated Stereotactic Radiosurgery: A Practical Approach to Guide Treatment of Brain and Spine Tumors, 1st Edition (e-Book) book cover

Image-Guided Hypofractionated Stereotactic Radiosurgery

A Practical Approach to Guide Treatment of Brain and Spine Tumors, 1st Edition

Edited by Arjun Sahgal, Simon S. Lo, Lijun Ma, Jason P. Sheehan

CRC Press

376 pages

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Hardback: 9781498722834
pub: 2016-04-27
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pub: 2016-03-23
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Description

The recent development of hypofractionated stereotactic radiation therapy (SRT), which calls for one to five fractions of high-dose radiation to be administered using special equipment, has resulted in the need for education on practice guidelines. Image-Guided Hypofractionated Stereotactic Radiosurgery: A Practical Approach to Guide Treatment of B

Table of Contents

Invited Perspectives on Hypofractionated Stereotactic Radiosurgery. Tumor Vascular Conundrum: Hypoxia, Ceramide, and Biomechanical Targeting of Tumor Vasculature. Gamma Knife: From Single-Fraction SRS to IG-HSRT. CyberKnife Image-Guided Hypofractionated Stereotactic Radiotherapy. Linac-Based IG-HSRT Technology. Advanced MRI for Brain Metastases. From Frame to Frameless: Brain Radiosurgery. Principles of Image-Guided Hypofractionated Stereotactic Radiosurgery for Brain Tumors. Principles of Image-Guided Hypofractionated Radiotherapy of Spine Metastases. Spine Stereotactic Body Radiotherapy for the Treatment of De Novo Spine Metastasis. Image-Guided Hypofractionated Stereotactic Radiotherapy for Reirradiation of Spinal Metastases. IG-HSRT for Benign Tumors of the Spine. Postoperative Spine IG-HSRT Outcomes. Postoperative Cavity Image-Guided Stereotactic Radiotherapy Outcomes. Brain Metastases Image-Guided Hypofractionated Radiation Therapy: Rationale, Approach, Outcomes. Image-Guided Hypofractionated Stereotactic Whole-Brain Radiotherapy and Simultaneous Integrated Boost for Brain Metastases. Image-Guided Hypofractionated Radiation Therapy for High-Grade Glioma. Benign Brain Tumors. Radiation Necrosis. Vertebral Compression Fracture Post-Spine SBRT. Spinal Cord Dose Limits for Stereotactic Body Radiotherapy. Summary of Image-Guided Hypofractionated Stereotactic Radiotherapy: Serious Late Toxicities and Strategies to Mitigate Risk.

About the Editors

Arjun Sahgal, MD (chief editor), is a leader in the field of high-precision stereotactic radiation to the brain and spine. After training at the University of Toronto, Ontario, Canada, in radiation oncology, he completed a fellowship at the University of California, San Francisco, in brain and spine radiosurgery with Dr. David Larson. Since then he has been recognized as a national and international clinical expert and research leader in radiosurgery. His main focus is on developing spine stereotactic body radiotherapy as an effective therapy for patients with spinal tumors. He has published numerous book chapters on the subject and more than 200 peer-reviewed papers in high-impact journals, including Journal of Clinical Oncology and The Lancet Oncology. He has edited or written several books specific to research on brain and bone metastases and is an editorial board member for several journals. He was chairman of the International Stereotactic Radiosurgery Society meeting (June 2013) and was a board member for the Brain Tumour Foundation of Canada and the International Stereotactic Radiosurgery Society. He has been invited to speak at several international meetings, has been a visiting professor at various universities, and leads several research groups. His further research activities involve integrating MRI into radiotherapy delivery, combining novel pharmacologic therapies with radiosurgery, and MRI-guided focused ultrasound.

Simon S. Lo, MD, is professor of radiation oncology at Case Western Reserve University, Cleveland, Ohio, and director of radiosurgery services and neurologic radiation oncology at University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio. Dr. Lo graduated from the Faculty of Medicine of The Chinese University of Hong Kong and did his residency in clinical oncology (Royal College of Radiologists, UK curriculum) at Queen Elizabeth Hospital, Hong Kong. He subs

Subject Categories

BISAC Subject Codes/Headings:
MED062000
MEDICAL / Oncology
MED085010
MEDICAL / Surgery / Neurosurgery
SCI055000
SCIENCE / Physics