Imaging in Cellular and Tissue Engineering: 1st Edition (Hardback) book cover

Imaging in Cellular and Tissue Engineering

1st Edition

Edited by Hanry Yu, Nur Aida Abdul Rahim

CRC Press

298 pages | 114 B/W Illus.

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Hardback: 9781439848036
pub: 2013-05-16
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pub: 2013-05-16
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Details on specific imaging modalities for different cellular and tissue engineering applications are scattered throughout articles and chapters in the literature. Gathering this information into a single reference, Imaging in Cellular and Tissue Engineering presents both the fundamentals and state of the art in imaging methods, approaches, and applications in regenerative medicine.

The book underscores the broadening scope of imaging applications in cellular and tissue engineering. It covers a wide range of optical and biological applications, including the repair or replacement of whole tissues (such as bone, cartilage, blood vessels, and bladder) and more novel artificially created support systems (such as artificial pancreas and bioartificial liver). Each chapter describes a particular application, relevant optical instrumentation, physical principles governing the imaging method, and strengths and weaknesses of the technique. The book also presents current and emerging data processing procedures.

As the field of tissue engineering moves from creating simpler outer body parts to more sophisticated internal organs, researchers need to evaluate and control how well the tissues are engineered and integrated into the living body. Suitable for both experts and newcomers in bioengineering and biomedical imaging, this book shows researchers how to apply imaging techniques to next-generation engineered cells and tissues. It helps them assess the suitability of specific imaging modalities for applications with various functional requirements.

Table of Contents


Introduction to Cellular and Tissue Engineering, Hanry Yu and Abhishek Ananthanarayanan

In Vitro Applications

Confocal Microscopy for Cellular Imaging: High-Content Screening, Baixue Zheng and Abhishek Ananthanarayanan

Use of Multiphoton Microscopy for Tissue Engineering Applications, Wei-Liang Chen, Hsuan-Shu Lee, and Chen-Yuan Dong

Two-Photon Microscopy for Surface Mapping and Organ Characterization, Anju Mythreyi Raja

Atomic Force Microscopy for Cell and Tissue Niche, Wanxin Sun

In Vivo Applications

Magnetic Resonance Imaging to Monitor Implanted Constructs, Nicholas E. Simpson and Athanassios Sambanis

Application of Imaging Technologies to Stem-Cell Tracking In Vivo, Sheng-Xiang Xie and Kishore Kumar Bhakoo

Computer Tomography and Micro-CT for Tissue Engineering Application, Zhang Zhiyong, Jerry K.Y. Chan, and Teoh Swee Hin

Intravascular Optical Coherence Tomography, Liu Linbo and Atsushi Tanaka

Imaging of Therapeutic Processes in Animals Using Optical Reporter Genes, Ying Zhao, Jiakai Lin, and Shu Wang

Imaging in Metabolic Medicine, Jinling Lu, Kishore Kumar Bhakoo, Kai-Hsiang Chuang, George K. Radda, Philip W. Kuchel, and Weiping Han

High-Resolution X-Ray Cone-Beam Microtomography, Xiaochun Xu and Ping-Chin Cheng

Data Analysis

Image Analysis for Cellular and Tissue Engineering, Shuoyu Xu, Piyushkumar A. Mundra, Huipeng Li, Shiwen Zhu, Roy E. Welsch, and Jagath C. Rajapakse


About the Editors

Hanry Yu is a professor in the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore. He is also the group leader in the Institute of Bioengineering and Nanotechnology (A*STAR), principal investigator in the Research Centre of Excellence in Mechanobiology, and visiting associate professor in the Department of Biological Engineering at the Massachusetts Institute of Technology. His research activities over the past decade involve interfacing biomaterials with tissue engineering. Dr. Yu earned a PhD in cell biology from Duke University.

Nur Aida Abdul Rahim was a postdoctoral researcher in the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore. Her research interests range from imaging intracellular fluorescent fusion protein interaction kinetics to stem cell migration and differentiation in microfluidic devices. She earned a PhD in mechanical engineering from the Massachusetts Institute of Technology.

About the Series

Series in Cellular and Clinical Imaging

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology