First Published in 1994, Inherited Disorders of the Thyroid System presents a thorough and comprehensive study of the biology of varied thyroid disorders illustrated by numerous tables and figures. This monograph begins with the initial step in thyroid hormone production and concludes with the interaction of the thyroid hormones with their target cells. The authors have been involved in research in this field for many years and help to bring together, in a single text, the widely scattered literature relevant to the disorders of the thyroid system.
"…this is an excellent book and is a must for every endocrinologist and neonatal screening laboratory. I would go as far as to say that it will also be very useful to the more classical specialists in inborn errors wishing to broaden their knowledge of the subject away from intermediary metabolism."
-G.M. Addison, J. Inher. Metab. Dis., 18 (1995) 650
Preface. A Retrospective View of the Inherited Errors of the Thyroid System. Familial Inherited TSH Deficiency. Thyroid Follicular Cell Unresponsiveness to TSH. The Iodide Transport Defect. Defective Organification of Iodide. The Pendred' Syndrome. Thyroglobulin Synthesis and Defects in Tg Gene Expression and Tg Secretion. The Iodotryrosine: Deiodinase Defect. The Syndromes of Reduced Responsiveness to Thyroid Hormone. Inherited Abnormalities in Thyroid Hormone Transport Proteins. Other Inherited Disorders of the Thyroid System. Thyroid Malignancy and Dyshormonogenetic Goiter.
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