Integrated Drug Discovery Technologies: 1st Edition (Paperback) book cover

Integrated Drug Discovery Technologies

1st Edition

By Houng-Yau Mei, Anthony W. Czarnik

CRC Press

576 pages

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Paperback: 9780367396268
pub: 2019-10-07
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Hardback: 9780824706494
pub: 2002-03-19
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Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.

Table of Contents

From gene to screen: target identification and validation Coupling Genotype to Phenotype; functional genomics; integrated proteomics technologies; where science meets silicone - microfabrication techniques and their scientific applications; SNP scoring for drug discovery applications; protein display chips; integrated proteomics technologies and in vitro validation of molecular tests. High throughput screening: high throughput screening as a discovery resource; fluorescence correlation spectroscopy (FCS) and FCS-related confocal fluorimetric methods (FCS + plus) multiple read-out options or miniaturized screening; homogeneous time-resolved fluorescence (HTRF); ADME-tox screening in drug discovery; screening lead compounds in the post-genomic era - an integrated approach to knowledge building from living cells.

About the Authors

Mei, Houng-Yau; Czarnik, Anthony W.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Pharmacy
SCIENCE / Chemistry / General