Integrative Therapies for Depression: Redefining Models for Assessment, Treatment and Prevention, 1st Edition (Hardback) book cover

Integrative Therapies for Depression

Redefining Models for Assessment, Treatment and Prevention, 1st Edition

Edited by James M. Greenblatt, Kelly Brogan

CRC Press

531 pages | 28 B/W Illus.

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pub: 2015-12-01
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Integrative Therapies for Depression: Redefining Models for Assessment, Treatment and Prevention summarizes emerging theories and research findings on various nonpharmaceutical therapies to treat mood disorders.

Supported by the review of nearly 3000 scientific studies, the book describes the concepts of inflammation, genetics, hormonal imbalance, gastrointestinal conditions, environmental stress, and nutritional deficiencies and their possible link to the pathogenesis of mood disorders.

It also examines findings on various nonpharmaceutical therapies used to treat mood disorders including vitamins, botanicals, and other natural products as well as exercise, stress reduction, bright light, mind-body practices, and spiritual approaches.

Also covered are evidence-based approaches to integrative management of mood disorders in pregnant women, adolescents, and the elderly. Separating facts from fiction, the book provides practical information that clinicians can implement and share with their patients.

The book fills a significant gap in the conventional model of therapeutics for mood disorders. It is a valuable resource for psychiatrists, psychologists, family therapists, and all other clinicians who devote their days to caring for those afflicted with depression.


"The sources of information are relevant and reliable, instilling confidence about the research presented, and the exceptional organization of the book makes it easy to browse topics quickly. Discussions of well-known therapies are accurate and complete, instilling further confidence about applying the principles. I would wholeheartedly recommend this book to other residents and psychiatrists as a relevant and useful guide." - Shayna Bailey, M.D (Pine Rest Christian Mental Health Services), Doody's Book Review Service

Table of Contents

Shifting the Paradigm: Redefining the Treatment of Mood Disorders

Emily Deans

The Role of Inflammation in Depression

Antolin C. Trinidad

The Gut-Brain Axis: The Role of the Gut in Brain Health

Court Vreeland and Kelly Brogan

Clostridia Bacteria in the GI Tract Affecting Dopamine and Norepinephrine Metabolism

William Shaw

Stress, Fear, Trauma, and Distress: Underlying Factors in Depression

Peter Bongiorno

Mitochondrial Dysfunction and Physiological Depression

Dean Raffelock

Micronutrient Deficiencies and Mitochondrial Dysfunction

Chandler Marrs

Vitamin Deficiencies and Depression: Evidence-Based Research

James Greenblatt and Priyank Patel

Mineral Deficiencies and Depression: Evidence-Based Research

James Greenblatt and Kayla Grossmann

Essential Fats and Amino Acids in Depression

Bettina Bernstein

Sex Steroids and Mood in Women

Ann Hathaway

The Hypothalamic-Pituitary-Adrenal Axis in Mood Disorders

Sara Gottfried

Adrenal, Reproductive, and Thyroid Hormone Testing for Depression

Dean Raffelock and Lara Pizzorno

Exposure to Toxic Chemicals as a Cause of Depression

William Shaw

Dietary Peptides and the Spectrum of Food Hypersensitivities

Cynthia Gariépy

Genetic-Based Biomarkers in Psychiatry: An Integrative Approach

Jay Lombard

Mood-Related Effects of Medications Prescribed for Non-Psychiatric Indications

Myrto A. Ashe

The Rationale for Treating with a Broad Spectrum of Minerals and Vitamins

Julia J. Rucklidge and Bonnie J. Kaplan

Amino Acids and Other Nutrients That Enhance the Synthesis and Regulation of Neurotransmitters

Richard M. Carlton

Botanicals for Depression: Rhodiola, St. John’s Wort, Curcumin, and Saffron

Judith E. Pentz

Exercise as an Adjunct to Treating Depression

Ralph E. Carson

The Role of Sleep and Light Therapy in Depression

Robin May-Davis

The Role of Spirituality and Religion in Depression and Treatment

Natalie L. Hill

Depression-Specific Yoga and Mindfulness-Based Cognitive Therapy Model: Description, Data on Efficacy, and Differences from Contemporary Models

Basant Pradhan

Meditation and Mindfulness

Healy Smith and Gregory Thorkelson

Narrative Therapy

Antolin C. Trinidad

Integrative Psychotherapy: Healing the MindBodyMatrix

Martha Stark

Integrative Approaches to Perinatal Depression

Vesna Pirec and Kelly Brogan

Integrative Approaches to Adolescent Depression

Amelia Villagomez and Noshene Ranjbar

Integrative Approaches for Geriatric Depression

Lewis Mehl-Madrona, Barbara Mainguy, and Asha Shah

Clinical Case Studies: Putting It All Together

Kat Toups

About the Editors

Edited by

James Greenblatt, MD, currently serves as chief medical officer and vice president of medical services at Walden Behavioral Care in Waltham, Massachusetts. Dr. Greenblatt is also an assistant clinical professor at Tufts University School of Medicine in Boston. Prior to joining Walden, he founded and served as the medical director of Comprehensive Psychiatric Resources, a private psychiatric practice focused on utilizing integrative medicine. A pioneer in the field of integrative medicine, Dr. Greenblatt has treated patients with mood disorders and complex eating disorders for more than 25 years. He has written several books and lectures throughout the United States on the scientific evidence for nutritional interventions in psychiatry and mental illness.

Kelly Brogan, MD, ABIHM, is a holistic women’s health psychiatrist on faculty at The George Washington University in Washington, DC, and in private practice in Manhattan, New York. Brogan has been a clinical instructor at New York University School of Medicine, where she did her fellowship and a residency in reproductive psychiatry. Her academic areas of interest include toxicology/environmental medicine, nutrition, inflammatory models of mental illness, autoimmunity, and epigenetics. She has published in the fields of psycho-oncology, women’s health, perinatal mental health, alternative medicine, and infectious disease. She is on the board of Green Med Info, Pathways to Family Wellness, NYS Perinatal Association, Functional Medicine University, Alternative Therapies in Health and Medicine, and Fisher Wallace, and is medical director for Fearless Parent.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Alternative Medicine
MEDICAL / Family & General Practice
MEDICAL / Psychiatry / General