Ion Mobility Spectrometry  book cover
3rd Edition

Ion Mobility Spectrometry

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ISBN 9781439859971
Published December 10, 2013 by CRC Press
444 Pages 155 B/W Illustrations

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Book Description

Since the turn of the twenty-first century, applications of ion mobility spectrometry (IMS) have diversified, expanding their utility in the military and security spheres and entering the realms of clinical practice and pharmaceutical exploration. Updated and expanded, the third edition of Ion Mobility Spectrometry begins with a comprehensive discussion of the fundamental theory and practice of IMS. Divided into four sections—Overview, Technology, Fundamentals, and Applications—the authors treat innovations and advances in all aspects of IMS in a fresh, thorough, and revised format.


  • Introduces the definitions, theory, and practice of IMS and summarizes its history from the beginnings of the study of ions to present commercial and scholarly activities
  • Presents the technology of IMS from a measurement perspective—covering inlet through ion formation, ion injection, electric fields, drift tube structures, and detectors
  • Covers the end results of measurement, the mobility spectrum, and the transformative trend of ion mobility: mass spectrometry
  • Discusses the influence on the experimental parameters on the mobility of ions

Mobility-based methods are no longer restricted to volatile substances and indeed the many benefits of this technology—simplicity, convenience, and the low cost of technology—have become recognized as meritorious in a wide range of uses. This is also true for the advantages of measurements—high speed, distinctive spectral features, and operation in ambient pressure with thermalized ions. Ion Mobility Spectrometry, Third Edition serves specialists in the field of IMS who are interested in the potential of recent developments and researchers, engineers, and students who want a comprehensive overview of this technology.

Table of Contents

Introduction to Ion Mobility Spectrometry. History of Ion Mobility Spectrometry. Sample Introduction Methods. Ion Sources. Ion Injection and Pulsed Sources. Drift Tubes in Ion Mobility Spectrometry. Ion Detectors. The Ion Mobility Spectrum. Ion Mobility-Mass Spectrometry. Ion Characterization and Separation: Mobility of Gas Phase Ions in Electric Fields. Control and Effects of Experimental Parameters. Detection of Explosives by IMS. Chemical Weapons. Drugs of Abuse. Pharmaceuticals. Industrial Applications. Environmental Monitoring. Biological and Medical Applications of IMS. Current Assessments and Future Developments in Ion Mobility Spectrometry.

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G.A. Eiceman is a professor at New Mexico University in Las Cruces.

Z. Karpas is an associate at the Nuclear Research Center in Beer-Shev, Israel.

Herbert H. Hill is a professor at Washington State University in Pullman.


"… an excellent book and essential for every researcher and engineer working in the field of ion mobility. The authors, who are leading experts in IMS technology, provide an excellent overview of the current state of science and technology related to IMS and the most recent developments in this field. … well written and easily understandable, with a well-balanced mix of practice-oriented information and theoretical background knowledge."
—Thomas Mayer, Department of Monitoring and Exploration Technologies, Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany, from International Journal for Ion Mobility Spectrometry, December 2014

Praise for the Previous Edition

"... The second edition of this book provides a timely update to the fundamental theory, advancements in instrumentation, and the development of new applications of IMS.... The book accomplishes the objectives outlined by the authors... The CD [is] a useful and practical addition to this book... Overall, this book should be useful to experts in IMS research as well as those new to the technology. As a practical book, it offers a well-balanced combination of theory and application... I highly recommend it to anyone interested in IMS."
—Robert G. Ewing, New Mexico Institute of Mining and Technology, in JACS, Vol. 128, 2006