Litt's Drug Eruption & Reaction Manual  book cover
26th Edition

Litt's Drug Eruption & Reaction Manual

ISBN 9780367438845
Published November 21, 2019 by CRC Press
502 Pages

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Book Description

Internationally relied upon by medical practitioners for its unparalleled focus on adverse effects and cutaneous reactions, Litt’s Drug Eruption & Reaction Manual is a succinct clinical reference and essential drug-safety tool for patient care. This 26th edition has been comprehensively revised and updated throughout to act as a quick reference, and each entry includes:
* Summaries of numbers of reports and incidence for reactions
* Clinically important and potentially hazardous drug–drug interactions
* Categories of adverse drug reactions, eruptions, and cutaneous reaction patterns
* Essential reference information on prescription and over-the-counter drugs as well as biologics and supplements

The book contains...

* A to Z listing of the 1500 most consulted generic drug and herbal drug profiles, including generic and trade names; pharmaceutical company; indications; half-life; interactions; pregnancy category; and categories of adverse reactions/eruptions, with summaries of number of reports or level of incidence of reaction
* Over 31,000 adverse reactions and drug-eruption listings
* Supplements, vaccines, and other biologics
* Descriptions of important reactions
* List of drugs that cause important reactions
* List of main classes of drugs as a quick clinical reference guide
* 26 tables showing the reaction profile for members of a class of drugs (such as ACE inhibitors or statins), enabling a clinician to see at a glance whether a reaction is common to all drugs included in that class, or to a majority of them, or is known in only a handful—this information can be used as the basis for an informed decision to change drugs inside the same class
* 2 tables showing reported genetic associations with cutaneous adverse drug reactions and recommendations regarding genetic screening to prevent cutaneous adverse drug reactions
* A concordance of synonyms and trade names for ease of cross-reference

Table of Contents

Introductory notes
Drug profiles: generic names
Descriptions of important reactions
Drugs that cause important reactions
Main classes of drugs
Class reactions
 ACE inhibitors
 Antibiotics, imidazole
 Antibiotics, macrolide
 Antidepressants, tricyclic
 Antihistamines (H1)
 Beta blockers
 Calcium channel blockers
 Corticosteroids, topical
 Disease-modifying antirheumatic drugs (DMARDS)
 DPP-4 inhibitors
 Epidermal growth factor receptor (EGFR) inhibitors
 Non-steroidal anti-inflammatory drugs (NSAIDS)
 Proton pump inhibitors (PPI)
 TNF inhibitors
 Tyrosine-kinase inhibitors
Genetic tables
Concordance of synonyms and trade names with
generic names

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Neil Shear, MD, FRCPC, is Head of Dermatology at Sunnybrook & Women’s College Health Sciences Centre and Director of the University of Toronto Drug Safety Research Group. He founded the Drug Safety Clinic at Sunnybrook in 1985 and was the founding chair of the Canadian Adverse Drug Reaction Advisory Committee (CADRAC) of Health Canada.