Lung Surfactant Function and Disorder: 1st Edition (Hardback) book cover

Lung Surfactant Function and Disorder

1st Edition

Edited by Kaushik Nag

CRC Press

528 pages | 6 Color Illus. | 118 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9780824757922
pub: 2005-05-13
SAVE ~$46.00
eBook (VitalSource) : 9780429115578
pub: 2005-05-13
from $28.98

FREE Standard Shipping!


The only source to describe the lung surfactant as a complex membranous system, this guide analyzes lung surfactant function from the aspects of molecular biology, biophysics, membrane science, and surface and interface analysis and reviews the latest basic and clinical issues relating to lung disease and (dys)function.


"…the book is comprehensive and covers all major areas of surfactant study."

-Books, Films, Tapes & Software

"…delves into the depths of the biology of pulmonary surfactant in respiratory diseases. The editor's intent to combine current observations regarding the biochemistry of pulmonary surfactants and the biophysics of surface tension phenomena is well-executed in this book."

-Doody's Reviews

Table of Contents

Composition, Structure, and Function. Lung Surfactant Phospholipid Molecular Species in Health and Disease. New Insights into Thermal Dynamics of the Surfactant System from Warm and Cold Animals. Molecular and Functional Properties of Surfactant Protein A. Receptors and Ligands for Collectin Surfactant Proteins A and D. Structure-Function Relationships of Hydrophobic Proteins SP-B and SP-C in Pulmonary Surfactant. Biophysics and Molecular Mechanisms. Chain Dancing, Super-Cool Surfactant, and Heavy-Breathing: Rafts, Membranes and Phase Transitions. The Basis of Low Surface Tension in the Lungs. Surfactant and Airway Liquid Flows. Lung Surfactants: A Molecular Perspective from Computation. Analysis of Surface Topology and Chemical Composition of Microstructures Formed in Planar Surfactant Films Under Compression. SP-B Peptides: Synthesis, Structure, and Surface Activity. Structure and Function of the Molecular Film of Pulmonary Surfactant at the Air-Alveolar Interface: The Role of SP-C. Analysis of SP-C Function in Transgenic and Gene Targeted Mice. Alternative Functions of SP-B and SP-C. Dysfunction and Disease. The Physiological Significance of a Dysfunctional Lung Surfactant. Pulmonary Surfactant in Asthma and Allergy. Surfactant Treatment for Inflammatory Lung Disease. Alteration of Alveolar Surfactant Function by Reactive Oxygen Species. Novel Surfactant Therapy for Developing Countries: Current Status and Future Directions

About the Series

Lung Biology in Health and Disease

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Pulmonary & Thoracic Medicine
MEDICAL / Surgery / General