Manual of Molecular and Clinical Lab Immunology: 8th Edition (Hardback) book cover

Manual of Molecular and Clinical Lab Immunology

8th Edition

By Barbara Detrick, Robert G. Hamilton, John L. Schmitz

ASM Press

1,240 pages

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Hardback: 9781555818715
pub: 2016-06-10
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Description

The Manual of Molecular and Clinical Laboratory Immunology is Regarded as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual of Molecular and Clinical Laboratory Immunology encompasses the exponential growth in the field of immunology over the past decades. This edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders. Written to guide the laboratory director, the Manual will also appeal to other laboratory scientists in clinical immunology laboratories, and pathologists. It is also a useful reference for physicians, mid-level providers, medical students, and allied health students. with an interest in the role that immunology plays in the clinical laboratory.

For over 40 years the Manual of Molecular and Clinical Laboratory Immunology has served as the premier guide for the clinical immunology laboratory. From basic serology testing to the present wide range of molecular analyses, the Manual has reflected the exponential growth in the field of immunology over the past decades. This eighth edition reflects the latest advances and developments in the diagnosis and treatment of patients with infectious and immune-mediated disorders.

The Manual features detailed descriptions of general and specific methodologies, placing special focus on the interpretation of laboratory findings, and covers the immunology of infectious diseases, including specific pathogens, as well as the full range of autoimmune and immunodeficiency diseases, cancer, and transplantation.

Table of Contents

DEBRA LONG PRIEL AND DOUGLAS B. KUHNS

section F

Cytokines and

Chemokines / 321

VOLUME EDITOR: BARBARA DETRICK

SECTION EDITOR: JOHN J. HOOKS

34 Introduction / 323

JOHN J. HOOKS

35 Multiplex Cytokine Assays / 324

ELIZABETH R. DUFFY AND DANIEL G. REMICK

36 Cytokine Measurement by Flow

Cytometry / 338

HOLDEN T. MAECKER

37 Chemokine and Chemokine Receptor

Analysis / 343

SABINA A. ISLAM, BENJAMIN D. MEDOFF, AND ANDREW D. LUSTER

38 Cytokines: Diagnostic and Clinical

Applications / 357

PRIYANKA VASHISHT AND TIMOTHY B. NIEWOLD

39 Detection of Anticytokine Autoantibodies and

Clinical Applications / 365

S ARAH K. BROWNE

section G

Immunohistology and

Immunopathology / 373

VOLUME EDITOR: ROBERT G. HAMILTON

SECTION EDITOR: R. NEAL SMITH

40 Introduction / 375

ROBERT G. HAMILTON

41 Immunofluorescence Methods in the Diagnosis

of Renal and Cardiac Diseases / 376

A. BERNARD COLLINS, JAMES R. STONE, AND

R. NEAL SMITH

42 Western Blot Analysis for the Detection

of Anti-Glomerular

Basement Membrane

Antibodies and Anti-Phospholipase

A2 Receptor

Antibodies / 385

A. BERNARD COLLINS AND R. NEAL SMITH

section H

Infectious Diseases Caused

by Bacteria, Mycoplasmas,

Chlamydiae, and

Rickettsiae / 391

VOLUME EDITOR: JOHN L. SCHMITZ

SECTION EDITOR: CHRISTINE M. LITWIN

43 Introduction / 393

CHRISTINE M. LITWIN

44 Diagnostic Methods for Group A Streptococcal

Infections / 394

CHRISTINE M. LITWIN, SHELDON E. LITWIN,

AND HARRY R. HILL

45 Diagnosis of Helicobacter pylori Infection and

Assessment of Eradication / 404

BRUCE E. DUNN AND SUHAS H. PHADNIS

46 Laboratory Diagnosis of Syphilis / 412

JOHN L. SCHMITZ

47 Lyme Disease, Relapsing Fever, and

Leptospirosis / 419

GUIQING WANG AND

MARIA E. AGUERO-ROSENFELD

48 Immunological Tests in Tuberculosis / 433

CHRISTINE M. LITWIN

49 Mycoplasma: Immunologic and Molecular

Diagnostic Methods / 444

KEN B. WAITES, MARY B. BROWN, AND

JERRY W. SIMECKA

50 Chlamydia and Chlamydophila

Infections / 453

ROSEMARY SHE

51 The Rickettsiaceae, Anaplasmataceae, and

Coxiellaceae / 461

LUCAS S. BLANTON AND DAVID H. WALKER

52 The Bartonellaceae, Brucellaceae, and

Francisellaceae / 473

CHRISTINE M. LITWIN, BURT ANDERSON,

RENEE TSOLIS, AND AMY RASLEY

section I

Mycotic and Parasitic

Diseases / 483

VOLUME EDITOR: ROBERT G. HAMILTON

SECTION EDITOR: THOMAS B. NUTMAN

53 Introduction / 485

THOMAS B. NUTMAN

54 Immunological and Molecular Approaches for

the Diagnosis of Parasitic Infections / 486

PATRICIA P. WILKINS AND THOMAS B. NUTMAN

55 Serological and Molecular Diagnosis of Fungal

Infections / 503

MARK D. LINDSLEY

section J

Viral Diseases / 535

VOLUME EDITOR: JOHN L. SCHMITZ

SECTION EDITORS: RICHARD L. HODINKA AND

JOHN L. SCHMITZ

56 Introduction / 537

JOHN L. SCHMITZ

57 Immunologic and Molecular Methods for Viral

Diagnosis / 538

MARIE LOUISE LANDRY AND YI-WEI

TANG

58 Herpes Simplex Virus / 550

D. SCOTT SCHMID

59 Varicella-Zoster

Virus / 556

D. SCOTT SCHMID

60 Epstein-Barr

Virus and Cytomegalovirus / 563

HENRY H. BALFOUR, JR., KRISTIN A. HOGQUIST,

AND PRIYA S. VERGHESE

Human Herpesviruses 6, 7, and 8 / 578

RICHARD L. HODINKA

62 Parvovirus B19 / 591

STANLEY J. NAIDES

63 Respiratory Viruses / 598

DAVID J. SPEICHER, MOHSIN ALI, AND

MAREK SMIEJA

64 Measles, Mumps, and Rubella Viruses / 610

DIANE S. LELAND AND RYAN F. RELICH

65 Viral Hepatitis / 620

HUBERT G. M. NIESTERS,

ANNELIES RIEZEBOS-BRILMAN,

AND

CORETTA C. VAN LEER-BUTER

66 Viral Agents of Gastroenteritis / 639

GABRIEL I. PARRA AND KIM Y. GREEN

67 Arboviruses / 648

ROBERT S. LANCIOTTI AND JOHN T. ROEHRIG

68 Diagnosis of Hantavirus Infections / 658

WILLIAM MARCIEL DE SOUZA AND

LUIZ TADEU MORAES FIGUEREIDO

69 Rabies Virus / 665

D. CRAIG HOOPER

70 Human T-Cell

Lymphotropic Virus

Types 1 and 2 / 674

BREANNA CARUSO, RAYA MASSOUD, AND

STEVEN JACOBSON

71 Diagnosis of Prion Diseases / 682

RICHARD RUBENSTEIN, ROBERT B. PETERSEN,

AND THOMAS WISNIEWSKI

72 Principles and Procedures of Human

Immunodeficiency Virus Diagnosis / 696

KELLY A. CURTIS, JEFFREY A. JOHNSON, AND

S. MICHELE OWEN

section K

Immunodeficiency

Diseases / 711

VOLUME EDITOR: BARBARA DETRICK

SECTION EDITORS: KATHLEEN E. SULLIVAN AND

HOWARD M. LEDERMAN

73 The Primary Immunodeficiency Diseases / 713

HOWARD M. LEDERMAN

74 Severe Combined Immune Deficiency: Newborn

Screening / 715

JAMES W. VERBSKY AND JOHN M. ROUTES

75 Combined Immunodeficiencies / 721

CHRISTINE SEROOGY AND MELISSA ELDER

76 Antibody Deficiencies / 737

KIMBERLY C. GILMOUR, ANITA CHANDRA, AND

D. S. KUMARARATNE

77 Hereditary and Acquired Complement

Deficiencies / 749

PATRICIA C. GICLAS

78 Neutropenia and Neutrophil Defects / 765

STEVEN M. HOLLAND

79 Evaluation of Natural Killer (NK) Cell

Defects / 774

KIMBERLY RISMA AND REBECCA MARSH

section L

Allergic Diseases / 781

VOLUME EDITOR: ROBERT G. HAMILTON

SECTION EDITOR: PAMELA A. GUERRERIO

80 Introduction / 783

PAMELA A. GUERRERIO

81 Quantitation and Standardization of

Allergens / 784

RONALD L. RABIN, LYNNSEY RENN, AND

JAY E. SLATER

82 Immunological Methods in the Diagnostic

Allergy Clinical and Research Laboratory / 795

ROBERT G. HAMILTON

83 Assay Methods for Measurement of Mediators

and Markers of Allergic Inflammation / 801

JOHN T. SCHROEDER, R. STOKES PEEBLES, JR.,

AND PAMELA A. GUERRERIO

84 Tests for Immunological Reactions to

Foods / 815

CARAH B. SANTOS, DAVID M. FLEISCHER, AND

ROBERT A. WOOD

85 Diagnosis of Rare Eosinophilic and Mast Cell

Disorders / 825

CEM AKIN, CALMAN PRUSSIN, AND

AMY D. KLION

section M

Systemic Autoimmune

Diseases / 839

VOLUME EDITOR: BARBARA DETRICK

SECTION EDITOR: WESTLEY H. REEVES

86 Introduction / 841

WESTLEY H. REEVES

87 Antinuclear Antibody Tests / 843

ALESSANDRA DELLAVANCE,

WILSON DE MELO CRUVINEL,

PAULO LUIZ CARVALHO FRANCESCANTONIO,

AND LUIS EDUARDO COELHO ANDRADE

88 Detection of Autoantibodies by Enzyme-Linked

Immunosorbent Assay and Bead Assays / 859

EDWARD K. L. CHAN, RUFUS W. BURLINGAME,

AND MARVIN J. FRITZLER

89 Immunodiagnosis and Laboratory Assessment of Systemic Lupus Erythematosus / 868

WESTLEY REEVES, SHUHONG HAN,

JOHN MASSINI, AND YI LI

90 Immunodiagnosis of Autoimmune

Myopathies / 878

MINORU SATOH, ANGELA CERIBELLI,

MICHITO HIRAKATA, AND EDWARD K. L. CHAN

91 Immunodiagnosis of Scleroderma / 888

MASATAKA KUWANA

92 Antibody and Biomarker Testing in Rheumatoid

Arthritis / 897

ANN DUSKIN CHAUFFE AND

MICHAEL RAYMOND BUBB

93 Antiphospholipid Antibody Syndrome: Clinical

Manifestations and Laboratory Diagnosis / 905

MARTINA MURPHY AND NEIL HARRIS

94 Antineutrophil Cytoplasmic Antibodies (ANCA)

and Strategies for Diagnosing ANCA-Associated

Vasculitides / 909

R. W. BURLINGAME, C. E. BUCHNER, J. G. HANLY,

AND N. M. WALSH

95 IgG4-Related

Disease: Diagnostic

Testing by Serology, Flow Cytometry, and

Immunohistopathology / 917

JOHN H. STONE

96 Future Perspectives for Rheumatoid Arthritis

and Other Autoimmune Diseases / 922

JEREMY SOKOLOVE

section N

Organ-localized

Autoimmune Diseases / 927

VOLUME EDITOR: JOHN L. SCHMITZ

SECTION EDITORS: C. LYNNE BUREK AND

PATRIZIO CATUREGLI

97 Introduction / 929

C. LYNNE BUREK

98 Endocrinopathies: Chronic Thyroiditis, Addison

Disease, Pernicious Anemia, Graves’ Disease,

Diabetes, and Hypophysitis / 930

C. LYNNE BUREK, N. R. ROSE,

GIUSEPPE BARBESINO, JIAN WANG,

ANDREA K. STECK, GEORGE S. EISENBARTH,

LIPING YU, LUDOVICA DE VINCENTIIS,

ADRIANA RICCIUTI, ALESSANDRA DE

REMIGIS, AND PATRIZIO CATUREGLI

99 Myasthenia Gravis / 954

ARNOLD I. LEVINSON AND ROBERT P. LISAK

100 Autoantibodies to Glycolipids in Peripheral

Neuropathy / 961

HUGH J. WILLISON

101 Detection of Antimitochondrial

Autoantibodies in Primary Biliary Cholangitis

and Liver Kidney Microsomal Antibodies in

Autoimmune Hepatitis / 966

PATRICK S. C. LEUNG, MICHAEL P. MANNS,

ROSS L. COPPEL, AND M. ERIC GERSHWIN

102 Cardiovascular Diseases / 975

CHERYL L. MAIER, C. LYNNE BUREK,

NOEL R. ROSE, AND AFTAB A. ANSARI

103 Celiac Disease and Inflammatory Bowel

Disease / 983

MELISSA R. SNYDER

104 Autoantibodies Directed against Erythrocytes

in Autoimmune Hemolytic Anemia / 990

R. SUE SHIREY AND KAREN E. KING

105 Immune Thrombocytopenia / 995

THOMAS S. KICKLER

106 Monitoring Autoimmune Reactivity within the

Retina / 998

JOHN J. HOOKS, CHI-CHAO

CHAN,

H. NIDA SEN, ROBERT NUSSENBLATT, AND

BARBARA DETRICK

section O

Cancer / 1005

VOLUME EDITOR: ROBERT G. HAMILTON

SECTION EDITORS: DANIEL CHAN AND

LORI J. SOKOLL

107 Introduction / 1007

ROBERT G. HAMILTON

108 Immunoassay-Based

Tumor Marker

Measurement: Assays, Applications, and

Algorithms / 1008

ELIZABETH A. GODBEY, LORI J. SOKOLL, AND

ALEX J. RAI

109 Malignancies of the Immune System: Use of

Immunologic and Molecular Tumor Markers in

Classification and Diagnostics / 1015

ELAINE S. JAFFE AND MARK RAFFELD

110 Monitoring of Immunologic Therapies / 1036

THERESA L. WHITESIDE

111 Circulating Tumor Cells as an Analytical

Tool in the Management of Patients with

Cancer / 1051

DANIEL C. DANILA, HOWARD I. SCHER, AND

MARTIN FLEISHER

section P

Transplantation

Immunology / 1063

VOLUME EDITOR: BARBARA DETRICK

SECTION EDITORS: ELAINE F. REED AND

QIUHENG JENNIFER ZHANG

112 Histocompatibility and Immunogenetics

Testing in the 21st Century / 1065

QIUHENG JENNIFER ZHANG AND

ELAINE F. REED

113 Molecular Methods for Human Leukocyte

Antigen Typing: Current Practices and Future

Directions / 1069

MARK KUNKEL, JAMIE DUKE,

DEBORAH FERRIOLA, CURT LIND, AND

DIMITRI MONOS

114 Evaluation of the Humoral Response in

Transplantation / 1091

PAUL SIKORSKI, RENATO VEGA,

DONNA P. LUCAS, AND ANDREA A. ZACHARY

115 Non-Human

Leukocyte Antigen Antibodies in

Organ Transplantation / 1103

ANNETTE M. JACKSON AND BETHANY L. DALE

116 Evaluation of the Cellular Immune Response in

Transplantation / 1108

DIANA METES, NANCY L. REINSMOEN, AND

ADRIANA ZEEVI

117 Complement in Transplant Rejection / 1123

CARMELA D. TAN, E. RENE RODRIGUEZ, AND

WILLIAM M. BALDWIN III

118 Molecular Characterization of Rejection in

Solid Organ Transplantation / 1132

DARSHANA DADHANIA, TARA K. SIGDEL,

THANGAMANI MUTHUKUMAR,

CHOLI HARTONO, MINNIE M. SARWAL, AND

MANIKKAM SUTHANTHIRAN

119 Killer Cell Immunoglobulin-Like

Receptors in

Clinical Transplantation / 1150

RAJA RAJALINGAM, SARAH COOLEY, AND

JEROEN VAN BERGEN

120 Chimerism Testing / 1161

LEE ANN BAXTER-LOWE

section Q

Laboratory

Management / 1169

VOLUME EDITOR: ROBERT G. HAMILTON

SECTION EDITOR: RONALD J. HARBECK

121 Clinical Immunology Laboratory

Accreditation, Licensure, and

Credentials / 1171

LINDA COOK AND RONALD J. HARBECK

122 Validation and Quality Control: General

Principles and Application to the Clinical

Immunology Laboratory / 1180

VIJAYA KNIGHT AND TERRI LEBO

Author Index / 1193

Subject Index / 1195

Subject Categories

BISAC Subject Codes/Headings:
SCI045000
SCIENCE / Life Sciences / Biology / Microbiology