First Published in 1992, Marijuana/Cannabinoids: Neurophysiology and Neurobiology is the first book to specifically address the effects of marijuana and cannabinoids on the physiology and behavior of the brain. The book discusses the dramatic effects of marijuana use on brain chemistry, pharmacology, and behavior. It also examines the isolation of natural cannabinoids and the synthesis of new cannabinoid-like compounds that have been important in research leading to the discovery and function of the cannabinoid receptor in the brain. Up-to-date research findings and in-depth reviews on marijuana and cannabinoids in the brain and their potential therapeutic value make Marijuana/Cannabinoids: Neurophysiology and Neurobiology essential for students, practitioners, and researchers involved in researching drugs of abuse.
Table of Contents
Cannabinoid Geometry and Biological Activity (R. Mechoulam, W.A. Devane, and R. Glaser). The Cannabinoid Receptor (A.C. Howlett, D.M. Evans, and D.B. Houston). Eicosanoids as Mediators of Cannabinoid Action (S. Burstein). Cannabinoid-Glucocorticoid Interactions in the Hippocampal Region of the Brain (J.C. Eldridge and P.W. Landfield). Maternal Cannabinoid Exposure and Brain Development: Changes in the Ontogeny of Dopaminergic Neurons (J.J. Fernández-Ruiz, F. Rodríguez de Fonseca, M. Navarro, and J.A. Ramos). In Vivo Interactions Between Psychotropic Cannabinoids and Other Drugs Involving Central and Peripheral Neurochemical Mediators (R.G. Pertwee). Behavioral, Neurochemical and Neurohistological Effects of Chronic Marijuana Smoke Exposure in the Nonhuman Primate (W. Slikker, Jr., M.G. Paule, S.F. Ali, A.C. Scallet, and J.R. Bailey). Cannabinoid Interaction With Brain Reward Systems-The Neurobiological Basis of Cannabinoid Abuse (E.L. Gardner). The Effects of Marijuana on Cerebral Blood Flow and Metabolism (R.J. Mathew and W.H. Wilson). Effects of Smoked Marijuana on Human Performance: A Critical Review (L.D. Chait and J. Pierri). Dissociative and Discriminative Stimulus Functions of Cannabinoids/Cannabimimetics (T.U.C. Järbe and D.A. Mathis). Potential Role of Cannabinoids for Therapy of Neurological Disorders (P. Consroe and R. Sandyk). Systemic Character of Mechanisms Mediating the Effects of Delta-9-Tetrahydrocannabinol on Behavior (A.I. Machula, S.M. Dudkin, and N.K. Barkov). Effects of Delta-9-Tetrahydrocannabinol on Pregnancy, Puberty and the Neuroendocrine System (T. Wenger, D. Croix, G. Tramu, and J. Leonardelli).
6-1/8 x 9-1/4, hardcopy, due July 1992, ISBN 0-8493-7931-8.
Laura Murphy, Andrzej Bartke