Mast Cell Proteases in Immunology and Biology
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This state-of-the-art reference provides timely and clinically and experimentally useful information on the major proteins of mast cell secretory granules that are released into the lung, skin, gut, eye, and other tissues under the influence of diverse stimuli-including cytokines, growth factors, neuropeptides, and allergen-bound immunoglobulin E.
Demonstrates the important roles proteases play in the maintenance of tissue homeostasis as well as in the damaging events linked with allergy and other varieties of inflammation!
Table of Contents
Mast Cell Proteases: A Historical Perspective, David Lagunoff
Mast Cell Tryptase: Properties and Roles in Human Allergic Responses, Lawrence B. Schwartz
Skin Tryptase: Features and Expression in Human Dermatological Disorders, Ilkka T. Harvima, Rauno J. Harvima, Anita Naukkarinen, and Maija Horsmanheimo
Chymotrypsin-like Proteinases of Human Skin Mast Cells, Norman M. Schechter
Mast Cell Neuropeptidases, Elizabeth K. Tam
Mast Cell Carboxypeptidase: Structure and Regulation of Gene Expression, Sanford M. Goldstein
Tissue and Development Variation of Protease Expression in Human Mast Cells, Anne-Marie A. Irani
Dog Mast Cell Proteinases in Models of Airway Secretion, Bronchoconstriction, Cutaneous Vascular Permeability, and Tissue Fibrosis, Christian P. Sommerhoff
Secretory Endo- and Exopeptidases of Mouse Mast Cells: Structure, Genetics, and Regulation of Expression, Eric B. Springman and William E. Serafin
Mast Cell Chymases in Helminthosis and Hypersensitivity, Hugh R.P. Miller, John F. Huntley, and George F.J. Newlands
Control of Tryptase and Chymase Activity by Protease Inhibitors, Hiroshi Kido and Nobuhiko Katunuma
Role of Mast Cell Proteases and Proteoglycans in Lipoprotein Metabolism, Jorma O. Kokkonen, Ken A. Lindstedt, and Petri T. Kovanen
Physiological Regulation of C3a Anaphylatoxin Activity by Mast Cell Chymase, Tony E. Hugli
Mast Cell Chymases and Tryptases: Phylogeny, Family Relations, and Biogenesis, George H. Caughey
Appendix: Mast Cell Protease Nomenclature and Abbreviations