1st Edition

Metabolism and Medicine
The Metabolic Landscape of Health and Disease (Volume 2)

  • Available for pre-order. Item will ship after November 12, 2021
ISBN 9780367699925
November 12, 2021 Forthcoming by CRC Press
464 Pages 267 B/W Illustrations

USD $150.00

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Book Description

Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. This book connects these insights to what causes them to go awry in the context of unhealthy human behaviors and aging, aiming to buttress scientific creativity. It also provides links between the art and science of medicine that strengthens problem-solving in patient care. New and important discoveries in the area of metabolic health and metabolic diseases are discussed in exquisite detail.

Key Features:

  • Broad and up-to-date overview of the field of metabolic aspects of health and chronic disease development, especially connecting the spectrum of topics that range from molecular clocks to stress response to nuclear hormone receptors and the role of microbiota in human health
  • Provides a deeper basic science and interdisciplinary understanding of biological systems that broaden the perspectives and therapeutic problem solving by elaborating on the usefulness of the Physiological Fitness Landscape
  • Describes the importance of insulin resistance in metabolic disease, especially diabetes but also includes links to cancer and Alzheimer’s disease
  • Examines the process of aging from the perspective of metabolic decline illustrating it with the Physiological Fitness Landscape

This book, the second volume in a two-volume set, primarily targets an audience of clinical and science students, biomedical researchers and physicians who would benefit from understanding each other’s language.

Table of Contents

1. Introduction to Metabolism - A New Model for Medicine 2. The Stress Response: From Health to Disease 3. Nuclear Hormone Receptors: Mediators of Dynamic (Patho)physiological Responses 4. The Biology of Time: How Molecular Clocks Make Living Cells Tick 5. Calorie Restriction, Intermittent Fasting, and Time-Restricted Feeding 6. The Microbiota, in Symbiotic Entanglement with Human Metabolism 7. The Role of Insulin Resistance in Metabolic Disease  8. Mitochondrial Function and Dysfunction and Insulin Resistance  9. Chronic Diseases of Aging as Metabolic Disorders 10. Epilogue

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Brian Fertig is a clinical endocrinologist, with almost 30 years of clinical experience. He is Chairman of the Department of Endocrinology at JFK Medical Center in Edison, New Jersey and Associate Professor of Medicine at Robert Wood Johnson University School of Medicine with an expertise in metabolism. Jack Tuszynski is a Fellow of the National Institute for Nanotechnology of Canada. He is an Allard Chair and Professor in Experimental Oncology in the Department of Oncology at the University of Alberta’s Cross Cancer Institute and a Professor in the Department of Physics.