Metal Ions in Biological Systems: Volume 42: Metal Complexes in Tumor Diagnosis and as Anticancer Agents, 1st Edition (Hardback) book cover

Metal Ions in Biological Systems

Volume 42: Metal Complexes in Tumor Diagnosis and as Anticancer Agents, 1st Edition

Edited by Helmut Sigel

CRC Press

600 pages

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Hardback: 9780824754945
pub: 2004-03-26
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Offering an authoritative and timely account by twenty-nine internationally recognized experts, Metal Ions in Biological Systems: Metal Complexes in Tumor Diagnosis and as Anticancer Agents is devoted solely to the vital research area concerning metal complexes in cancer diagnosis and therapy. In fourteen stimulating chapters, the book focuses on diagnostic tools such as magnetic resonance imaging (MRI), luminescent probes, and radiopharmaceuticals, including radiometallo-labeled peptides and assesses the role of metal ions, especially iron, in the action of antibiotics employed in anticancer chemotherapy.


"This is one of two recent volumes in a most successful series publishes since 1973 and which enjoys world renown and respect as both reference and as training material; the current volume is no exception. … [T]his is a gem of a book for both newcomers and established researchers in the field; long may they continue!"

- Applied Organometallic Chemistry, 2005

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Table of Contents

Magnetic Resonance Contrast Agents for Medical and Molecular Imaging, M.J. Allen and T.J. Meade

Luminescent Lanthanide Probes as Diagnostic and Therapeutic Tools, J.-C. Bünzli

Radio-Lanthanides in Nuclear Medicine, F. Rösch and E. Forssell-Aronson

RadioMetallo-Labeled Peptides in Tumor Diagnosis and Therapy, M. Ginj and H.R. Maecke

Cisplatin and Related Anticancer Drugs. Recent Advances and Insights, K.R. Barnes and S.J. Lippard

The Effect of Cytoprotective Agents in Platinum Anticancer Therapy, M.A. Jakupec, M. Galanski, and B.K. Keppler

Antitumor Activity of Trans-Platinum Species, G. Natile and M. Coluccia

Polynuclear Platinum Drugs, N.P. Farrell

Platinum(IV) Anticancer Complexes, M.D. Hall, R. Dolman, and T.W. Hambley

Ruthenium Anticancer Drugs, E. Alessio, G. Mestroni, A. Bergamo, and G. Sava

Antitumor Titanium Compounds and Related Metallocenes, F. Caruso and M. Rossi

Gold Complexes as Antitumor Agents, L. Messori and G. Marcon

Gallium and Other Main Group Metal Compounds as Antitumor Agents, M.A. Jakupec

Metal Ion Dependent Antibiotics in Chemotherapy, D.H. Petering, C. Xia, and W.E. Antholine

About the Series

Metal Ions in Biological Systems

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biochemistry
MEDICAL / Oncology
SCIENCE / Chemistry / Inorganic