Microcapsules and Nanoparticles in Medicine and Pharmacy  book cover
1st Edition

Microcapsules and Nanoparticles in Medicine and Pharmacy

ISBN 9780367244057
Published May 23, 2019 by CRC Press
347 Pages

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Book Description

First published in 1992: This book provides a comprehensive look at the design and production of microcapsules, microspheres, and nanoparticles. It discusses the diverse aspects and skills that must be mastered to prepare and test products that will work correctly and be clinically acceptable for human or animal use.

Table of Contents

1. Introduction and Overview

Max Donbrow

Part 1: Advances in Production Technology and Characterization Of Microcapsules, Microspheres, and Nanoparticles

2. Developments in Phase Separation Methods, Aggregation Control, and Mechanisms of Microencapsulation

Max Donbrow

3.Formation of Degradable Drug-Loaded Microparticles by In-Liquid Drying Processes

Curt Thies

4. Fluid-Bed Spray Coating

K. Lehmann

5. Polyanhydride Microspheres as Drug Delivery Systems

Edith Mathiowitz and Robert Langer

6. Nanoparticles - Preparation and Applications

J. Kreuter

7. Recent Advances Using Microencapsulation for Taste Masking of Bitter Drugs

J.A. Bakan et al.

Part 2: Biological Transit and Interactions, Release Kinetics, Pharmacokinetics And Bioavailability

8. Gastrointestinal Transit of Microcapsules

John T. Fell

9. Interaction of Microcapsules with Blood Components

Tamotsu Kondo

10. Recent Advances in Microencapsulation of Drugs to Obtain Reduced Gastric Irritation

J.A. Bakan et al.

11. In Vitro Release from Microcapsules and Microspheres

Ivan Jalsenjak

12. The Relation of Release Profiles from Ensembles to Those of Individual Microcapsules and the Influence of Types of Batch Heterogeneity on Release Kinetics

Max Donbrow

13. Pharmacokinetic Considerations Related to Bioavailability of Sustained-Release Microencapsulated Drugs for Oral Use - Assessment of Absorption Rates

Shigeru Goto and Takahiro Uchida

Part 3: Clinical Applications, Targeting, and Living and Artificial Encapsulated Cells.

14. Clinical Uses of Microcapsules and Microspheres

Kazuhiko Juni and Masahiro Nakano

15. Chemo-Embolization and Passive Targeting with Degradable Starch Microspheres

Peter Edman and Ingvar Sjöholm

16. Active Targeting of Microcapsules and Microspheres to Specific Regions

Julia J. Wright and Lisbeth Illum

17. Erythrocytes as Microvesicles

David A. Lewis and H. Oya Alpar

18. Microencapsulation of Living Cells and Tissues.

Anthony M. Sun, Ivan Vacek, and Isaballa Tai

19. Recent Advances in Artificial Cells with Emphasis on Biotechnological Approaches Based on Microencapsulation

Thomas Ming Swi Chang

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Max Donbrow, Ph.D., D.Sc., is Professor of Pharmacy at the Hebrew University of Jerusalem, Jerusalem, Israel.