Completely updated with contributions by world leaders in surgery and the surgery specialties, this reference assists surgeons in the diagnosis and treatment of patients by considering disease as a derangement of normal physiology, thus allowing the surgeon to correlate the appropriate use of laboratory and radiologic modalities. Arranged according
GENERAL CONSIDERATIONS IN THE MANAGEMENT OF SURGICAL PATIENTS. Metabolic Response to Starvation, Stress and Sepsis. Pathophysiology of Fluid and Electrolyte Disorders. Surgical Nutrition.The Immune System and the Immunocompromised Patient. Physiologic Basis of Transplantation. Surgical Infection: Principles of Management and Antibiotic Usage. Hemostasis and Thrombosis in the Surgical Patient. Pathophysiology of Shock. Neoplastic Disease: Pathophysiology and Rationale for Treatment. Physiology of Anesthesia and Pain. Sepsis and the Syndrome of Multiple Organ Failure. Application of Cellular and Molecular Biology to Surgical Care. Physiologic Principles in Preparing Patients for Surgery. THE ALIMENTARY TRACT. Esophagus and Stomach. Physiologic Dysfunction of the Esophagus. Gastric Physiology and Acid-Peptic Disorders. Small and Large Intestine. Physiology of Digestion and Absorption. Intestinal Circulation and Vascular Disorders of the Splanchnic Vascular Bed. Inflammatory Disorders of the Small Bowel and Colon. Liver, Biliary Tract, Pancreas and Spleen. Hepatic Physiology. Portal Hypertension. Calculous Disease of the Gallbladder and Common Bile Duct. Normal Exocrine Function and Inflammatory Diseases of the Pancreas. The Jaundiced Patient. The Spleen. Other Conditions. Gastrointestinal Hemorrhage. Anatomy, Physiology and Differential Diagnosis of Acute Abdominal Pain. Neoplastic Disorders of the Gastrointestinal Tract. Mechanical Disorders of the Stomach, Duodenum, and Intestine. Physiologic Derangements of the Anorectum and the Defecatory Pelvic Floor. Derangements in Gastrointestinal Function Secondary to Previous Surgery. THE CARDIOTHORACIC SYSTEM. Lung. Pathobiology of Surgically Relevant Lung Disease. Heart. Normal Cardiac Function. Heart Failure and Resuscitation. Mechanical Support of the Failing Heart: Current Physiologic Concepts and PART. THE URINARY SYSTEM. Urine Formation: From Normal Physiology to Florid Renal Failure. Urinary Tract Obstruction.