Molecular techniques are being harnessed for the detection of organisms in a wide range of circumstances. Global trade has introduced new pests of crops and plants; simultaneously, there is universal concern from disease outbreaks such as BSE, Foot & Mouth and the bird-flu virus. Molecular diagnostic applications for the detection of foodborne bacterial pathogens and genetically modified organisms in food are also becoming increasingly important.
This book provides a critical assessment of the various molecular methods in medical and veterinary science, forensics, biodefense, plant science, food safety and quarantine sciences. Aimed at graduates, postdoctoral research scientists, established researchers and specialist scientists, the book describes and evaluates molecular techniques and applications in this increasingly important area.
Topics include the molecular methods for the direct detection of pathogens such as E. coli O157:H7, MRSA and other important bacterial infections, medical viruses, medical parasites, dental plaque bacteria and haematological malignancies. Also covered is the molecular recognition and detection of catastrophic bio-threat agents as a consequence of global terrorism.
Section 1: Applications to Plant and Animal Health 1. Update on Molecular Tools for Detection of Plant Pathogenic Bacteria and Viruses 2. Molecular Diagnostic Tools for Detection of Plant Pathogenic Fungi 3. Application of Molecular Techniques for Detection of Bacterial Veterinary Pathogens Section 2: Applications to Food Safety (Foodborne Pathogens, Pests, GMO) 4. Molecular Diagnostics and Epidemiological Typing Methods for Common Foodborne Pathogens Campylobacter and Salmonella 5. DNA Biosensor Chips for GMO Detection 6. Molecular Techniques for Identification of Quarantine Insects and Mites: The Potential of Microarrays Section 3: Applications to Biomedical and Clinical Sciences 7. Biosensor Applications of Peptide Nucleic Acid for Direct Detection of PCR Amplified DNA of Pathogens E. coli 0157:H7 and MRSA 8. Molecular Diagnostics of Medically Important Bacterial Infections 9. Molecular Diagnostic Tools for the Detection of Bacteria in Dental Plaque 10. Molecular Investigations of Haematological Malignancies 11. Molecular Diagnosis of Medical Viruses 12. Molecular Diagnosis of Parasites of Medical Importance Section 4: Applications to Biothreats, Drugs and Forensics 13. Applications of Biosensor Technology for Molecular Recognition and Detection 14. Molecular Diagnosis and Bioterrorism: An Update