Molecular Dissection of Complex Traits: 1st Edition (Hardback) book cover

Molecular Dissection of Complex Traits

1st Edition

By Andrew H. Paterson

CRC Press

336 pages

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Hardback: 9780849376863
pub: 1997-08-29
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Description

In the past 10 years, contemporary geneticists using new molecular tools have been able to resolve complex traits into individual genetic components and describe each such component in detail. Molecular Dissection of Complex Traits summarizes the state of the art in molecular analysis of complex traits (QTL mapping), placing new developments in this field within the context of their historical origins. Leading authorities address central themes in analysis of complex phenotypes, and case histories of important work in this burgeoning field are presented by the principal investigators.

The book is divided into three sections:

Table of Contents

Introduction

Of Blending, Beans, and Bristles: The Foundations of QTL Mapping, A.H. Paterson

Fundamental Principles

Molecular Tools for the Study of Complex Traits, M.D. Burow and T.K. Blake

Experimental Design Considerations in Analysis of Complex Traits, G.A. Churchill and R.W. Doerge

Computational Tools for Study of Complex Traits, B.-H. Liu

QTL Mapping in Outbred Pedigrees, C.G. Williams

Mapping QTLs in Autopolyploids, S.-C. Liu, Y.-R. Lin, J.E. Irvine, and A.H. Paterson

QTL Analysis under Linkage Equilibrium, J.F. Taylor and J.L. Rocha

Molecular Analysis of Epistasis, Z. Li

QTL Mapping in DNA Marker-Assisted Plant and Animal Improvement, A.H. Paterson

QTL Analyses: Power, Precision, and Accuracy, W.D. Beavis

High-Resolution Mapping of QTLs, A.H. Paterson

Compilation and Distribution of Data on Complex Traits, D.W. Bigwood

Case Histories

Case History in Plant Domestication: Sorghum, An Example of Cereal Evolution, A.H. Paterson, K.F. Schertz, Y. Lin , and Z. Li

Case History in Crop Improvement: Yield Heterosis in Maize, C.W. Stuber

Case History in Germplasm Introgression: Tomato Genetics and Breeding Using Nearly Isogenic Introgression Lines Derived from Wild Species, D. Zamir and Y. Eshed

Case History in Genetics of Long-Lived Plants: Molecular Approaches to Domestication of a Fast-Growing Forest Tree: Populus, T. Bradshaw

Case History in Animal Improvement: Mapping Complex Traits in Ruminants, M. Georges

Case History in Animal Improvement: Genetic Mapping of QTLs for Growth and Fatness in the Pig, L. Andersson et al.

Case History in Humans: Mapping QTLs for Complex Traits in Humans, H. Sakul and L.R. Cardon

Social Impact of QTL Mapping

From Malthus to Mapping: Prospects for an Impact of Genome Analysis on the World Food Supply, J. Xiao and S.R. McCouch

Ethical Consequences of Mapping QTLs for Complex Human Traits, J.C. Crabbe and J.K. Belknap

Epilogue

Prospects for Cloning the Genetic Determinants of QTLs, A.H. Paterson

Index

Subject Categories

BISAC Subject Codes/Headings:
SCI011000
SCIENCE / Life Sciences / Botany
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
SCI049000
SCIENCE / Life Sciences / Biology / Molecular Biology