Multidisciplinary Applications and Advances in Biotechnology Contributions from the Biotechnology Society of Nigeria Working Groups, Six-Volume Set

Volume 1: Fermentation and Algal Biotechnologies for the Food, Beverage and Other Bioproduct Industries
Foreword
Ashiwin Vadiveloo
Preface
Benjamin Ewa Ubi
Part 1: Working Group 01: Dairy and Fermented Foods
Handling Editor: James C. Ogbonna
1. Improving Traditionally Fermented African Foods Through Biotechnology - Need to translate art to science
Philippa C. Ojimelukwe
2. Indigenous fermented and underutilized /novel foods with potentials for combating malnutrition in sub-Saharan Africa
Philippa C. Ojimelukwe
3. Biotechnologies / fermentation technologies for large-scale industrial enzyme production for the food and beverage industry
Olusola Oyewole, Sarafa O. Kareem, Tolulope Adeleye
4. Recent Advances in Dairy Industries: Monitoring, Standard, Quality and Process
Charles Oluwaseun Adetunji, Olugbemi Tope Olaniyan, Kingsley Eghonghon Ukhurebor, Julius Kola Oloke, Olaleye Olusola, Benjamin Ewa Ubi, Daniel Ingo Hefft
5. Soy-based Food Products Consumed in Africa: A Panacea to mitigate Food Insecurity and Health Challenges
Olugbemi T Olaniyan, Charles Oluwaseun Adetunji, Juliana Bunmi Adetunji, Julius Kola Oloke, Olaleye Olusola, Daniel Ingo Hefft, Benjamin Ewa Ubi
6. Nutritional and Health Benefits of Nutraceutical Beverages Derived from Cocoa and other Caffeine Products: Comprehensive review
Juliana Bunmi Adetunji, Charles Oluwaseun Adetunji, Saher Islam, Devarajan Thangadura, Olugbemi T Olaniyan, Florence U. Masajuwa, Olaleye Olusola, Daniel Ingo Hefft, Wadazani Palnam Dauda, Benjamin Ewa Ubi
7. Strategies For Yeast Strain Improvement Through Metabolic Engineering
Ogbulie, Toochukwu Ekwutosi, Opara, Christiana N, Nwachukwu, Augusta Anuli and Ogbodo, Priscilla Amaka
8. The role of an intelligent feedback control system in the standardization of bio-fermented food products
Charles Oluwaseun Adetunji, Wilson Nwankwo, Kingsley E. Ukhurebor, Samuel Makinde, Olugbemi T Olaniyan, Florence U. Masajuwa, Benjamin Ubi
Part 2: Working Group 3: Microalgae and novel products
Handling Editor: Emeka G. Nwoba
9. Algae biotechnology for novel foods
Mathias A. Chia, Emeka G. Nwoba, James C. Ogbonna
10. Microalgae biotechnology research and development opportunities in Nigeria
James C. Ogbonnaa, Emeka G. Nwobab, David Chuka-Ogwudeb, Innocent Ogbonnac, Abosede T. Adesalud
11. Emerging eco- and bio-technologies in the use of algal biomass for biofuels and high-value products
Taofikat A. Adesalu, Mathias A. Chia, John N. Idenyi, Emeka G. Nwoba
12. African mushrooms as functional foods and nutraceuticals: A review of their farm to fork perspectives
Charles O. Adetunji, Juliana B. Adetunji, Olugbemi T. Olaniyan, Osarenkhoe O. Osemwegie, Benjamin E. Ubi

Volume 2: Agricultural biotechnology, biodiversity and bio-resources conservation and utilization
Foreword
Francis C. Ogbonnaya
Preface
Benjamin Ewa Ubi
Part 1: Crop Genetics, Breeding & Genomics Working Group
Handling Editor: Olawole Obembe
1. Biotechnology As A Tool For Agricultural Revolution In Developing Nations: Current Status And Bottlenecks In Nigeria
S. T. Akinyosoye, J. A. Adetumbi
2. Advances On Engineering Cassava For Food And Nutrition Security In 21st Century
Nneka R. Okereke, Ihuoma C. Okwuonu, C. N. Egesi, J. T. Onyeka, Akinola Popoola
3. Current and Future Advances in Genomics-Assisted Cassava Breeding
S. P. Abah, L. Ezenwaka, D. Njoku, Ihuoma C. Okwuonu, T. J. Onyeka, C. N. Egesi
4. Genome Engineering: A New Frontier For Improving Root And Tuber Crops
Ihuoma C. Okwuonu, J. E. Obidegwu, C. N. Egesi, T. J Onyeka, V. N. Otang
5. Development And Commercialization Of Bt-Cowpea In Nigeria: Implication For National Development
L. M. Umar, B. S. Mohammed, M. F. Ishiyaku, C. A. Prince, K. A. Issoufou, R. S. Adamu, I. M. Utono, N. O. Francis, O. Bolarinwa
6. Progress In The Development Of Bio-Fortified Sorghum In Nigeria: Implications For Food And Nutrition Security
Yeye, M. Y, Aba, D.A., Kwanashe, A. J., Wambugu, F., Aseta, A.,Obukosa, S.,Albertsen M. C., and Zhao, Z.Y
7. Strategies For The Production Of Disease-Free Yam Planting Materials – Implications For Improved Yam Production In Nigeria
EDAK ANIEDI UYOH, VALENTINE OTANG NTUI1, EFFIOM EYO ITA
8. Engineering Pests And Disease Resistance In Crops: From RNA Interference To RNA Editing
Yakubu Abubakar Saddeeq, Abdulrazak B. Ibrahim and Joshua Ehis Imonmion
9. Engineering Crops For Resistance To Pests And Diseases: Necessity For Crop Improvement Through Accurate Genomic Resources And Phenotyping
O. Kolade, O. Daniel, D. O. Igwe
10. Molecular Diagnostics For Plant Viruses Towards Enhanced Delivery Of Disease-Free Planting Materials And Germplasm Exchange
Kolade O.A., Popoola A. R. Igwe, D. O. and Adediji A
11. Recent Advances In Molecular Techniques For The Enhancement Of Crop Production
Charles Oluwaseun Adetunji, Olugbemi Tope Olaniyan, Kingsley Eghonghon Ukhurebor, Benjamin Ewa Ubi, Julius Kola Oloke, Wadzani Palnam Dauda, Daniel Ingo Hefft
Part 2: Animal Genetics, Breeding & Genomics
Handling Editor: Emmanuel O. Ekundayo, Benjamin Ewa Ubi
12. Genetic Intervention In Sustainable Livestock Production
Cyril Otoikhian, Etta, Hannah, Olorunleke, Solomon and Ikpeme, Ekei
13. Development Of Improved Indigenous Chickens (Funaab Alpha) For Smallholder Poultry Production In Nigeria
Olufunmilayo A. Adebambo, S. O. Peters, A. O. Adebambo, M. A. Adeleke, M. Y. Wheto, O. Kehinde, Jessie E. Udoh
14. Biotechnology Applications In Livestock Production
Olufunmilayo A. Adebambo; Victor E. Olori Sunday O. Peters; Ayotunde O. Adebambo; Mathew Wheto
15. Enabling Environment For Uptake Of Biotechnological Innovations For Livestock Production In Africa
Victor E. Olori
16. Biothermoimaging Tools For Management Of Climate Smart And Precision Livestock Assisted Reproduction
Mustapha Ayodele Popoola, Sulaiman Elias Bogoro, Jean Magloire Feugang
Part 3: Genetic Resources Conservation and Enhancement
Handling Editor: Benjamin Ewa Ubi
17. Securing The Genetic Base Of Indigenous Food Plants: Their Role In Promoting Sustainable Food Systems
Andrew Chibuzor Iloh, George Ude and Christie Onyia
18. Biotechnology-Aided Sustainable Use Of Nigeria’s Biodiversity For Improved Nutrition And Health
Pamela Akin-Idowu, Lovina Iyandu Udoh, Dorcas Olubunmi Ibitoye
19. Utilizing Plant Genetic Resources To Develop Climate Resilient Crops
Mba, C. and Ogbonnaya, F. C.
20. Biodiversity And Genetic Resources Conservation In Nigeria
George Nkem Ude, David Okeh Igwe, Christie Oby Onyia, Chosen Ekene Obih
21. Biotechnological Approaches For Genetic Resources Conservation And Use
Aladele S.E, Afolayan G., Jamaleddine Z. O., Oduoye O. T., Bolatito O. A., Afolayan A. O., Daniel I.O., Olosunde A. A1., Olubiyi M.R., Okere A. U and Ubi B. E.

Volume 3: Medical Biotechnology, Biopharmaceutics, Forensic Science and Bioinformatics
Foreword
Alex U. Akpa
Preface
Benjamin Ewa Ubi
Part 1: Working Group 04: Molecular Diagnostics and DNA Forensics
Handling Editor: Prof. Ifeoma Ezeonu
1. Principles and Techniques for Deoxyribonucleic Acid (DNA) Manipulation
Nwadiuto Esiobu, Ifeoma Ezeonu, Francisca Nwaokorie
2. Forensic DNA profiling and molecular identification of infectious pathogens: The Nigeria experience.
D. E. Agbonlahor, M. Y. Tatfeng, I. B. Enweani-Nwokelo, I. Ezeonu, E. A. Brisibe, F. O. Nwaokorie, N. Esiobu, A. O. Eremwanarue, F. E. Oviasogie, G. S. George, B. E. Ubi
3. DNA markers in forensic and diagnostic science
M. Y. Tatfeng, D. E. Agbonlahor, I. B. Enweani-Nwokelo, I. Ezeonu, F. Nwaokorie, E. A. Brisibe, D. Esiobu
4. Legal standards setting in the use of Forensics DNA Barcode: Evidence for wildlife crime detection and prosecution in Nigeria
Christie O. Onyia, Obianuju P. Ilo, Scott E. Miller
Part 2: Working Group 07: Medical and Pharmaceutical Biotechnology
Handling Editor: Prof. Mairo Hajiya Inuwa
5. Harnessing Indigenous Bioresources for Development of Diagnostics for Detection and  Confirmation of Infectious agents in Nigeria
E. O. Ekundayo, J. C. Igwe, I. Ezeonu
6. Antibiotic Resistance: Global Trends, Impact And Mitigation
I. M. Ezeonu, I. R. Iroha, N. Esiobu
7. Safeguarding Nigeria Territory from the use of antibiotic resistant microbes in bioterrorism
J. C. Igwe, E. O. Ekundayo, I. Ezeonu, S. K. Parom
8. Deep Learning and Economic Prospects in Medical and Pharmaceutical Biotechnology
Charles Oluwaseun Adetunji, Olugbemi Tope Olaniyan, Kingsley Eghonghon Ukhurebor, Adetunji Julianah Bunmi, Gloria E Okotie, Julius Kola Oloke
9. Health and Nutritional benefits of numerous bioactive components derived from fish and fish products
Juliana Bunmi Adetunji, Charles Oluwaseun Adetunji, Michael Olugbenga Samuel Genevieve Dable-Tupas, Chukwuebuka Egbuna
10. Repositioning antiviral drugs as a rapid and cost-effective approach to discover treatment against SARS-CoV-2 infection
Omotayo O. Oyedara, Folasade M. Adeyemi, Charles Oluwasun Adetunji, Elufisan Temidayo Oluyomi
11. Corn Silk and Health Benefits
Adetunji Charles Oluwaseun, Michael Olugbenga Samuel, Adetunji Juliana Bunmi, Oluranti OlufemiIdowu
12. Bioengineering of Pharmacologically-Active Metabolites for Effective Drug Nano Formulations from the Callus of Medicinal Plants and their Significant Application in Nanomedicine: Recent Advances
Charles Oluwaseun Adetunji, Denisa Ficai, Anton Ficai,, Olugbenga Samuel Micheal, Wilson Nwankwo, Muhammad Akram, Chukwuebuka Egbuna, Oluwaseyi Paul Olaniyan, Rumaisa Ansari, Hameed Shah, Tehreen Riaz, Ruth Ebunoluwa Bodunrinde, Rida Zainab, Juliana Bunmi Adetunji, Jonathan C. Ifemeje, Mohammad Ali Shariati, Michael Chinedu Olisah, Akinola Samson Olayinka, Kingsley Eghonghon Ukhurebor, Daniel Ingo Hefft and Wadzani Dauda Palnam
Part 3: Omics and Bioinformatics
Handling Editor: Charles Oluwaseun Adetunji
13. Bioinformatics: a tool for biotechnological advancement
Oyawoye O. M., Olorunsola H. A, Oluduro A. O. Bamigboye O. O, Oladipo E.K., Olotu T. M., Adeosun I. J., Kaka M. O., Obembe O. O.
14. Role of Nucleotide Sequence Analysis in Human Genetics and Genomics
S. S. D. Mohammed, I. Abraham, D. Enoma, L. E. Okoror
15. Application of Computational and bioinformatics techniques in drug repurposing for effective development of potential drug candidate for the management of COVID-19
Charles Oluwasun Adetunji, Olaniyan T Olugbemi, Muhammad Akram, Umme Laila, Olugbenga Samuel Michael, Ayomide Michael Oshinjo, Julianah BunmiAdetunji, Gloria E Okotie, Nwadiuto Esiobu, Folasade Muibat Adeyemi, Omotayo Opemipo Oyedara
16. Computational Intelligence Techniques for Combating COVID 19
Charles Oluwasun Adetunji, Wilson Nwankwo, Akinola Samson Olayinka, Olaniyan T Olugbemi, Muhammad Akram,Umme Laila, Olugbenga Samuel Michael,Ayomide Michael Oshinjo, Julianah BunmiAdetunji,Gloria E Okotie, Nwadiuto Esiobu
17. Machine learning and behavior modification for COVID 19
Charles Oluwasun Adetunji, Wilson Nwankwo, Akinola Samson Olayinka, Olaniyan T Olugbemi, Muhammad Akram,Umme Laila, Olugbenga Samuel Michael,Ayomide Michael Oshinjo, Julianah BunmiAdetunji,Gloria E Okotie, Nwadiuto Esiobu
Part 4: Working Group 12: Medicinal and Underutilized Plants
Handling Editor: Prof. Abubakar Gidado
18. Underutilized plant species, a huge potential for economic development in Nigeria
Friday Nwalo Nweke, Godwill Azeh Engwa and Oluchi Cynthia Abiamere
19. The place of neglected legumes in human nutrition and food security
Beckley Ikhajiagbe, Geoffrey Obinna Ikhajiagbe, Anoliefo, Doris I. Omoigui, Edokpolor Osazee Ohanmu, Saheed Ibrahim Musa and Zipporah Emilomo Omage
20. Antiprotozoal Activity of medicinal plants against Entamoebahistolytica, the causative agent of amoebiasis
IFEOMA B. ENWEANI-NWOKELO, UGOY SONIA A. OGBONNA, GRACE I. OKWU, ONYEKACHUKWU O. ENWEANI
21. Harnessing benefits of underutilized Plant Species for Economic Growth in Nigeria
Oluwafemi Abiodun Adepoju, Bashiru Ibrahim, and Emmanuel Oluwadare Balogun
Part 5: Working Group 13: Medical Insect Biotechnology, Genomics and Molecular Genetics of pests
Handling Editor: Dr. Abdulrazak Ibrahim
22. Exploiting Arthropod midgut components for development of interventions against infectious diseases
Charles Oluwaseun Adetunji, Oyetunde T. Oyeyemi
23. Genome-based Vector Surveillance for Effective Prediction and Control of Mosquito-Borne Viral Disease Outbreaks in Nigeria
Nwadiuto Esiobu, Bamidele Oderinde, Njidda Gadzama, Ihekerenma Okoli

Volume 4: Biosafety and Bioethics in Biotechnology
Foreword
Bamidele Ogbe Solomon
Preface
Benjamin Ewa Ubi
Part 1: Biosafety, Bioethics and Legal Issues in Biotechnology.
1. Status of Nigeria’s Biosafety Regulation.
Rufus Ebegba, Scholastica Bello, and Joy Onwude
2. CRISPR / Cas9: Regulatory Considerations to Ensure Safety of Gene-Edited Products in Nigeria.
Sylvia Uzochukwu, Arinze S. Okoli
3. Regulating Gene-Edited Products in Nigeria.
Rufus Ebegba, Joy Onwude
4. Emerging Technologies: Can African Regulator Take a Lead on Transgenic Mosquito Regulation.
Rufus Ebegba, Joy Onwude
5. Bioethics: Principles and Practice in The Face of Modern Technology.
Charles Oluwaseun Adetunji, Kingsley Eghonghon Ukhurebor, Olugbemi Tope Olaniyan, Olugbenga Samuel Micheal, Julius Kola Oloke, Benjamin Ewa Ubi
Part 2: Biotechnology Policy Advocacy, Enlightenment and Public Engagement with Stakeholders / Policy Makers.
6. Science Communication in Agricultural Biotechnology and Public Engagement with Stakeholders in Nigeria.
R. S. M. Gidado, A. Isah, J. C. Igwe, S. O. O. Iweajunwa, N. Muchiri
7. Biotechnology Development in Nigeria: Meeting Critical Developmental Needs.
A. Akpa, Benjamin E. Ubi, Christie Onyia, Nwadiuto Esiobu, Abdulrazak Ibrahim
8. Communicating Scientific Innovations: The Case of Agricultural Biotechnology in Nigeria.
R.S.M. Gidado, A. Isah, S. O. O. Iweajunwa, N. Muchiri
9. Review of Biotechnology Policies and Regulatory Frameworks.
James C. Ogbonna, Benjamin E. Ubi, Abdulrazak Ibrahim, Ebiamadon Andi Brisibe; Abubakar Gidado, Aliyu Daja, Mwajim Bukar
Part 3: Biotechnology Education and Curriculum Development.
10. Current status of Biotechnology Manpower Development in Nigeria.
Olu Odeyemi, Modupe Stella Ayilara
11. Strategies Towards Enhancing Biotechnology Training in Nigeria.
Sylvia Uzochukwu, Christie Onyia, Nwadiuto Esiobu, Joan Campbell, Paul Keese, Ivan Ingelbrecht and Alex Ochem
12. Challenge of Science, Technology Engineering and Mathematics (Stem) in Technological Development of Nigeria.
Nwadiuto Esiobu, Ivar Virgin

Volume 5: Microbiomes and Emerging Applications
Preface
Emeka I Nweze
Foreword
Benjamin Ewa Ubi
1. Microbiome and Metagenomics researches in Nigeria: evolution, current status and prospects
Francisca O. Nwaokorie, Ime R. Udotong, Nwadiuto Esiobu and Ifeoma Enweani Nwokelo
2. Microbial Biotechnology: Expanding the Frontiers of Microbiomes for Innovations in Agriculture and Medicine
Obembe, O. O., Esiobu, N., Aworunse, O. S. and Agbakoba, N. R.
3. The need for Probiotics in Nigeria
Kingsley C Anukam and Nneka R Agbakoba
4. Development And Composition Of The Human Microbiome From Birth
Toochukwu E. Ogbulie, Nwadiuto Esiobu and Muinah Foworah
5. Microbiota Transplantation, Health Implications and the Way Forward
Olugbenga S. Michael, Charles O. Adetunji, Olufemi I. Oluranti, Julianah B. Adetunji, Oshinjo M. Ayomide, Esiobu Nwadiuto
6. Microbiome Reshaping and Epigenetic Regulation
Olugbenga S. Michael, Charles O. Adetunji, Kehinde S. Olaniyi, Julianah B. Adetunji, Olufemi I. Oluranti, Oshinjo M. Ayomide
7. Probiotic Research Studiesthat Led to the Discovery of Lactobacillus pentosus KCA1
Kingsley C Anukam
8. A Brief Review of Earth Microbiomes and Applications
Toochukwu E. Ogbulie, Nwadiuto Esiobu and Ifeoma Enweani

Volume 6: Bioenergy and environmental biotechnology for sustainable development
Foreword
Jerry O. Ugwuanyi
Preface
Benjamin Ewa Ubi
Part 1: Waste recycling, biofuels and environmental remediation
Handling Editor: Akinola Popoola
1. Bio-resources utilization in fostering a low-carbon renewable energy – based economy
Olu Odeyemi, Modupe Stella Ayilara, Mobolaji Adenike Titilawo, Oluwaseyi Samuel Olanrewaju
2. Biomethanization in anaerobic systems: feedstock and process enhancement
N. C. Ezebuiro, C. O. Onyia, I. Koerner
3. Appraising the bioactivity potentials of eco-friendly synthesized metallic nanoparticles
Mike O. Ojemaye, Anthony I. Okoh
4. Enhancement of bioprocesses for the reclamation of impacted environment
Beckley Ikhajiagbe, Geoffrey Obinna Anoliefo, Francis AibuedefeIgiebor
5. Potential of some indiginous bacterial isolates in the development of bioenhancement formulations for bioremediation of nydrocarbon impacted environments
M.B. Yerima, A. O. Adeleye, Kingsley Nwagwu, M. E. Nkereuwem, V. O. Onokebhagbe, Rebecca Richard, I. K. Adam, A. F. Umar, A. A. Farouq
6. Environmental reclamation in Nigeria: past, present and future
Beckley Ikhajiagbe, Geoffrey O. Anoliefo, Ogochukwu F. Olise, Isaac J. Adekunle
Part 2: Water and Waste Water Recycling
Handling Editor: Abdulrazak Ibrahim
7. Sustainable wastewater treatment using microalgae technology
Emeka G. Nwoba, John N. Idenyi, Christiana N. Ogbonna, Mathias A. Chia, James C. Ogbonna
8. New insights into chlorine disinfectant usage in water quality: a need for review of existing guidelines
Mojisola Owoseni, Anthony I Okoh

Biography

Benjamin Ewa Ubi Ph.D., is a Professor of Plant Breeding and Biotechnology and currently serves as the President of the Biotechnology Society of Nigeria (BSN).

Sylvia Uzochukwu is a professor of Food Science and Technology and Dean at Federal University, Oye-Ekiti.

Emeka Godfrey Nwoba, Ph.D. is a research scholar at Algae R &D Centre, Murdoch University, Australia.

Charles Oluwaseun Adetunji Ph.D., is an Associate Professor of Microbiology and Biotechnology at the Microbiology Department, Faculty of Science, Edo University Iyamho (EUI), Edo State, Nigeria.

Nwadiuto Esiobu, Ph.D. is Professor of Microbiology and Biotechnology at Florida Atlantic University, Boca Raton, FL, USA; and President & Founder, Applied Biotech Inc. and ABINL.

Professor Olawole Obembe, received his Ph..D from Wageningen University, The Netherlands. His research interest include ethnopharmacology, in vitro conservation and micro-propagation of endangered (medicinal) plants, production of bio-pharmaceutics and industrial proteins in plants, quantitative trait loci analysis and genome-wide association studies.

Abdulrazak Ibrahim, Ph.D. is an agricultural biotechnologist with experience and skills on plant biotechnology stewardship, stakeholder engagement, foresight analysis, development of transgenic crops, laboratory and field management of GM crops, biosafety analysis, adoption and discontinuation of events.

Emmanuel Olufemi Ekundayo currently works at the Department of Microbiology/Centre for Molecular Biosciences and Biotechnology, Michael Okpara University of Agriculture, Umudike.

Arinze Stanley Okoli, Ph.D.: is an Associate Professor at Genoek - Centre for Biosafety, Universitetet II, Breivika, Tromsoe, Norway.

Abubakar Gidado, Ph.D. is a professor of Biochemistry and Director North-East Zonal Biotechnology Centre of Excellence (NEZBCE) at University of Maiduguri.

Prof. Hajia Mairo Inuwa, is currently Director, Centre for Biotechnology Research and Training, Ahmadu Bello University.

Professor Ifeoma Maureen Ezeonu, B.Sc. (Nig.), M.Sc., Ph.D. (Atlanta) is a Professor of Medical Microbiology and Molecular Genetics in the Department of Microbiology, University of Nigeria, Nsukka and currently the Director of the University of Nigeria Central Science Laboratory.

Christpeace Nwagbo Ezebuiro, Ph.D. is a Project Manager, Renewable Energy Expert and Head of Clean Technology Division at the National Biotechnology Development Agency, Abuja, Nigeria.

James Chukwuma Ogbonna, Ph.D. is the Director, National Biotechnology Development Agency, South East Zonal Biotechnology Centre, University of Nigeria, Nsukka, and the immediate past Deputy Vice Chancellor (Academic), University of Nigeria Nsukka.

Akinola R. Popoola, Ph.D. is a Professor of Plant Pathology and the Director, Biotechnology Centre, Federal University of Agriculture, Abeokuta, Nigeria.