Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles—their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs.
Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery.
Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.
Table of Contents
Polymeric Nanoparticles: General Features, Polymers, and Formulation Aspects
Marcos Luciano Bruschi, Lizziane Maria Belloto De Francisco, and Mônica Villa Nova
Nanoparticles in Drug Delivery: General Characteristics, Applications, and Challenges
Nanoparticles as Nanopharmaceuticals: Smart Drug Delivery System
Md. Sahab Uddin
Nanoparticles Advance Drug Delivery for Cancer Cells
Hani Nasser Abdelhamid and Hui-Fen Wu
Nanotechnology Based Formulations for Drug Targeting to CNS
Josef Jampílek and Katarína Kráľová
Magnetic Nanoparticles for Drug Delivery
Meenakshi Ponnana and Lakshmi Kiran Chelluri
Overview of Applications of Gold Nanoparticles in Therapeutics
Juliana Palma Abriata, Marcela Tavares Luiz, Giovanni Loureiro Raspantini, Josimar O. Eloy, Raquel Petrilli, Juliana Maldonado Marchetti, and Robert Lee
Superparamagnetic Iron Oxide Nanoparticles (SPIONs): Application in Diagnosis and Therapy of Cancer
Solid Lipid Nanoparticles: General Aspects, Preparation Methods and Applications in Drug Delivery
Marcos Luciano Bruschi, Hélen Cássia Rosseto, and Lucas De Alcântara Sica De Toledo
Solid Lipid Nanoparticles in Drug Delivery for Skin Care
Sheefali Mahant, Sunil Kumar, Rakesh Pahwa, Deepak Kaushik, Sanju Nanda, and Rekha Rao
Dendrimers in Gene Delivery
Bhupinder Kaur, Surya Prakash Gautam, Ranjit Singh, and Narinder Kumar
Carbon Nanotubes for Drug Delivery: Focus on Antimicrobial Activity
Márcia Ebling De Souza, Dariane Jornada Clerici, and Roberto Christ Vianna Santos
Raj K. Keservani, MPharm, is associated with the Faculty of B. Pharmacy, CSM Group of Institutions, Allahabad, India. He has more than 10 years of academic experience in various institutes of India imparting pharmaceutical education. He has published 35 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals, 16 book chapters, two coauthored books, and 10 edited books. He is also active as a reviewer for several scientific international journals. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), transdermal drug delivery/drug delivery, health science/life science, and biology/cancer biology/neurobiology. Mr. Keservani graduated (B. Pharmacy) from the Department of Pharmacy, Kumaun University, Nainital, Uttarakhand, India, in 2005. Afterwards, he qualified GATE in the same year, conducted by IIT Mumbai. He received his Master of Pharmacy (M. Pharmacy) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh, India, in 2008 with a specialization in pharmaceutics.
Anil K. Sharma, MPharm, PhD, is currently working as an assistant professor at the Department of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram, India. He has more than nine years of academic experience in pharmaceutical sciences. He graduated (B. Pharmacy) from the University of Rajasthan, Jaipur, India, in 2005. Afterwards, he qualified GATE in same year, conducted by IIT Mumbai. He received his Master of Pharmacy (M. Pharmacy) from the School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal, Madhya Pradesh, India, in 2007, with a specialization in pharmaceutics. He earned his PhD from the University of Delhi. In addition, he has published 29 peer-reviewed papers in the field of pharmaceutical sciences in national and international reputed journals, 15 book chapters, and 10 edited books. His research interests encompass nutraceutical and functional foods, novel drug delivery systems (NDDS), drug delivery, nanotechnology, health science/life science, and biology/cancer biology/neurobiology.
"The rapid development of nanotechnology during the past several years has demonstrated that this technology holds the key to stealth drug delivery systems. This book emphasizes the basic principles of nanotechnology applied to
drug delivery systems. In this context, this book may be a useful reference to students planning on working with nanoparticulatesystems."
Rahmat M. Talukder, PhD, RPh (The University of Texas at Tyler)