Jenny Stanford Publishing
240 pages
Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack
Lipoplexes and Polyplexes: From Gene Delivery to Gene Expression. Cationic Polymers for the Delivery of Therapeutic Nucleotides. Membrane/Core Nanoparticles for Delivery of Therapeutic Nucleic Acid. Delivery of Single siRNA Molecules. Cell-Specific Aptamer-Functionalized RNAi: A New Prospect for Targeted siRNA Delivery. Bioresponsive Nanoparticles for the Intracellular Delivery of RNAi Therapeutics. Lipid-Like Delivery Materials for Efficient siRNA Delivery. Manipulation of Leukocytes Using Therapeutic RNAi Delivered by Targeted and Stabilized Nanoparticles. Lowering the siRNA Delivery Barrier: Alginate Scaffolds and Immune Stimulation.