Abortion is a worldwide problem in the livestock industry accounting for annual economic losses of billions of dollars, and N. caninum is a major cause of it. Neosporosis is a newly recognized disease of animals. Until 1988 it was misdiagnosed as toxoplasmosis. Considerable progress in understanding the biology of neosporosis has been made in the last 30 years, resulting in more than 2,000 scientific publications. The economic importance of abortion in cattle, and the availability of knowledge, reagents, and technology used to study toxoplasmosis, have contributed to the rapid progress in understanding the biology of neosporosis.
Written by pioneers in this field, Neosporosis in Animals presents a comprehensive summary of the biology of neosporosis, starting with chapter 1 on the historical background of the discovery of the disease. Subsequent chapters deal with general aspects of the biology of N. caninum (chapter 2), techniques (chapter 3), and the disease caused by this parasite in cattle (chapter 4), dogs (chapter 5), and all other animals including sheep, pigs, primates and humans (chapters 6-18).
This book provides, for the first time in a single authoritative source, a complete account of the structure, biology, clinical disease, diagnosis, epidemiology, treatment, attempts at immunoprophylaxis, and control in all hosts. There are 175 illustrations and tables devoted to the life cycle, structure of parasitic stages, and lesions. More than 2100 references are cited, allowing the reader to locate additional information on specific topics in an efficient way. This book will be useful to a broad range of researchers in biology and veterinarians.
Table of Contents
History of Neospora and Neosporosis
Landmarks in the Biology of Neospora
Life Cycle Stages
Transmission and Epidemiology
Molecular and Cell Biology
Rodent Models of Neosporosis
Bioassay of Tissues for Isolation of Neospora
Neosporosis in Cattle
Economics and Control of Bovine Neosporosis
Neosporosis in Dogs
Diagnosis of Canine Neosporosis and Canine N. caninum Infection
Neosporosis in Sheep
Immunity, Protection, and Vaccination
Neosporosis in Goats
Neosporosis in Watter Buffaloes (Bubalus bubalis)
Neosporosis in Pigs
Neosporosis in Camels and South American Camelids
Neosporosis in Felids
Neosporosis in Avian Species
Neosporosis in Humans and Primates
Neosporosis in Humans
Experimental Neosporosis in Rhesus Monkeys
Neosporosis in Cervids and Other Wild Herbivores
Natural Infections in Cervids
Neosporosis in White Rhinoceros (Ceratotherium simum)
Neosporosis in Wild Canids and Other Carnivores
Other Wild Carnivores
Neosporosis in Miscellaneous Animals
Giant Panda (Ailuropoda melanoleuca)
Parma Wallaby (Macropus parma)
N. hughesi and Neosporosis in Horses and Other Equids
Differences Between N. hughesi and N. caninum
Natural Infections in Horses
J. P. Dubey, M. V. Sc. Ph.D., was born in India. He received his veterinary degree in 1960, and Masters in Veterinary Parasitology in 1963, from India. He obtained a Ph.D. in Medical Microbiology in 1966 from the University of Sheffield, England. He obtained post doctoral training with Dr. J. K. Frenkel, Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City, from 1968 to 1973. From 1973 to 1978, he was Associate Professor of Veterinary Parasitology, Department of Pathobiology, Ohio State University, Columbus. He was Professor of Veterinary Parasitology, Department of Veterinary Science, Montana State University, Bozeman, from 1978 to 1982. He is presently a Senior Scientist, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.
Dr. Dubey has spent over 50 years researching protozoa, including Toxoplasma, Neospora, Sarcocystis and related cyst-forming coccidian parasites of humans and animals. He has published over 1400 research papers in international journals, more than 200 of which are on neosporosis. In 1985 he was chosen to be the first recipient of the “Distinguished Veterinary Parasitologist Award” by the American Association of Veterinary Parasitologists. Dr. Dubey is recipient of the 1995 WAAVP Pfizer Award for outstanding contributions to Research in Veterinary Parasitology. He also received the 2005 Eminent Parasitologists Award by the American Society of Parasitologists. The Thomas/Institute for Scientific Information identified him as one of the world’s most cited authors in plant and animal sciences for the last decade. In 2010, he was elected to the U.S. National Academy of Sciences, Washington, D.C., and inducted in the USDA-ARS Hall of Fame.