Neosporosis in Animals  book cover
1st Edition

Neosporosis in Animals

ISBN 9781498752541
Published May 4, 2017 by CRC Press
530 Pages - 14 Color & 63 B/W Illustrations

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Book Description

Key features:

  • Written by the scientist who named this parasite and was the first to set up proper diagnostic techniques
  • Serves as the first ever book to provide information on the parasite structure, biology, pathogenesis, clinical signs, epidemiology, prevention, and control of neosporosis
  • Covers both approaches toward preventing & controlling this disease: Developing an efficacious vaccine and sound cattle management practices
  • Contains a wealth of illustrations, including many of the author's original photographs of the parasite
  • Provides basic information on immunologic and molecular aspects of the disease

    Abortion is a worldwide problem in the livestock industry accounting for annual economic losses of billions of dollars, and N. caninum is a major cause of it. Neosporosis is a newly recognized disease of animals. Until 1988 it was misdiagnosed as toxoplasmosis. Considerable progress in understanding the biology of neosporosis has been made in the last 30 years, resulting in more than 2,000 scientific publications. The economic importance of abortion in cattle, and the availability of knowledge, reagents, and technology used to study toxoplasmosis, have contributed to the rapid progress in understanding the biology of neosporosis.

    Written by pioneers in this field, Neosporosis in Animals presents a comprehensive summary of the biology of neosporosis, starting with chapter 1 on the historical background of the discovery of the disease. Subsequent chapters deal with general aspects of the biology of N. caninum (chapter 2), techniques (chapter 3), and the disease caused by this parasite in cattle (chapter 4), dogs (chapter 5), and all other animals including sheep, pigs, primates and humans (chapters 6-18).


    This book provides, for the first time in a single authoritative source, a complete account of the structure, biology, clinical disease, diagnosis, epidemiology, treatment, attempts at immunoprophylaxis, and control in all hosts. There are 175 illustrations and tables devoted to the life cycle, structure of parasitic stages, and lesions. More than 2100 references are cited, allowing the reader to locate additional information on specific topics in an efficient way. This book will be useful to a broad range of researchers in biology and veterinarians.

    Table of Contents

    History of Neospora and Neosporosis


    Landmarks in the Biology of Neospora

    General Biology


    Taxonomic Classification


    Life Cycle Stages

    Transmission and Epidemiology

    Host-Parasite Relationship

    Molecular and Cell Biology

    Rodent Models of Neosporosis

    General Diagnosis



    Prevention, Prophylaxis


    Bioassay of Tissues for Isolation of Neospora

    Parasite Cultures

    Diagnostic Procedures


    Neosporosis in Cattle

    Natural Infections

    Experimental Infections



    Economics and Control of Bovine Neosporosis

    Neosporosis in Dogs

    Natural Infections

    Diagnosis of Canine Neosporosis and Canine N. caninum Infection



    Experimental Infections

    Neosporosis in Sheep

    Natural Infections

    Experimental Infections

    Immunity, Protection, and Vaccination

    Neosporosis in Goats

    Natural Infections

    Experimental Infections

    Neosporosis in Watter Buffaloes (Bubalus bubalis)

    Natural Infections

    Experimental Infections

    Neosporosis in Pigs

    Natural Infections

    Experimental Infections

    Neosporosis in Camels and South American Camelids

    Natural Infections

    Neosporosis in Felids

    Natural Infections

    Experimental Infections

    Neosporosis in Avian Species

    Natural Infections

    Experimental Infections

    Neosporosis in Humans and Primates

    Neosporosis in Humans

    Experimental Neosporosis in Rhesus Monkeys

    Neosporosis in Cervids and Other Wild Herbivores

    Natural Infections in Cervids

    Other Cervids

    Other Herbivores

    Neosporosis in White Rhinoceros (Ceratotherium simum)

    Neosporosis in Wild Canids and Other Carnivores

    Wild Canids

    Other Wild Carnivores

    Neosporosis in Miscellaneous Animals

    Giant Panda (Ailuropoda melanoleuca)

    Parma Wallaby (Macropus parma)

    Marine Mammals

    Small Mammals

    N. hughesi and Neosporosis in Horses and Other Equids


    Differences Between N. hughesi and N. caninum

    Natural Infections in Horses

    Experimental Infections


    View More



    J. P. Dubey, M. V. Sc. Ph.D., was born in India. He received his veterinary degree in 1960, and Masters in Veterinary Parasitology in 1963, from India. He obtained a Ph.D. in Medical Microbiology in 1966 from the University of Sheffield, England. He obtained post doctoral training with Dr. J. K. Frenkel, Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City, from 1968 to 1973. From 1973 to 1978, he was Associate Professor of Veterinary Parasitology, Department of Pathobiology, Ohio State University, Columbus. He was Professor of Veterinary Parasitology, Department of Veterinary Science, Montana State University, Bozeman, from 1978 to 1982. He is presently a Senior Scientist, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland.

    Dr. Dubey has spent over 50 years researching protozoa, including Toxoplasma, Neospora, Sarcocystis and related cyst-forming coccidian parasites of humans and animals. He has published over 1400 research papers in international journals, more than 200 of which are on neosporosis. In 1985 he was chosen to be the first recipient of the “Distinguished Veterinary Parasitologist Award” by the American Association of Veterinary Parasitologists. Dr. Dubey is recipient of the 1995 WAAVP Pfizer Award for outstanding contributions to Research in Veterinary Parasitology. He also received the 2005 Eminent Parasitologists Award by the American Society of Parasitologists. The Thomas/Institute for Scientific Information identified him as one of the world’s most cited authors in plant and animal sciences for the last decade. In 2010, he was elected to the U.S. National Academy of Sciences, Washington, D.C., and inducted in the USDA-ARS Hall of Fame.