Neural Plasticity and Memory: From Genes to Brain Imaging, 1st Edition (Hardback) book cover

Neural Plasticity and Memory

From Genes to Brain Imaging, 1st Edition

Edited by Federico Bermudez-Rattoni

CRC Press

368 pages | 8 Color Illus. | 49 B/W Illus.

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Hardback: 9780849390708
pub: 2007-04-17
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Description

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies.

The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function.

Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

Table of Contents

SEARCHING FOR MEMORY IN THE BRAIN: CONFRONTING THE COLLUSION OF CELLS AND SYSTEMS, J.L. McGaugh

One Hundred and Fifty Years of Controversy

The Great Debate: What is Learned - Knowledge or Responses?

Brain Systems and Forms of Memory

Brain Systems and Memory Functions.

Cells and Systems

Two Centuries of Progress in Research on Brain and Memory

References

LONG-TERM POTENTIATION AND DEPRESSION AS PUTATIVE MECHANISMS FOR MEMORY FORMATION, M.L. Escobar and B. Derrick

Introduction

Long-Lasting Forms of Synaptic Modification: A Methodological Approach

LTP and LTD: Triggering, Expression, and Maintenance Mechanisms

Persistent Synaptic Plasticity: A Metaplastic Point of View

The Role of Activity-Dependent Synaptic Plasticity in Brain Function

Substrates of LTP and LTD - Structural Plasticity

Neurotrophins and Synaptic Plasticity

Experience-Dependent Modifications - Is LTP Involved in Learning and Memory?

Outstanding Questions and New Directions

MOLECULAR MECHANISMS OF SYNAPTIC PLASTICITY UNDERLYING LONG-TERM MEMORY FORMATION, V. Ramirez-Amaya

Early Signals.

Ca2+ and its transducer

Immediate early genes.

Trophic Factors.

Conclusions

MODIFICATION OF BRAIN CIRCUITS THROUGH EXPERIENCE, M.R. Rosenzweig

Brain Plasticity Discovered through Serendipity

Unexpected Discovery of Brain Plasticity

Cerebral Effects of Experience Occur in All Species Tested

Enriched Environments and the Brain

Neurochemical Cascades Underlie Modification of Neural Circuits

Acknowledgments

References

PRESYNAPTIC STRUCTURAL PLASTICITY AND LONG-LASTING MEMORY: FOCUS ON THE LEARNING-INDUCED REDISTRIBUTION OF HIPPOCAMPAL MOSSY FIBERS, J.L. Rekart, M.R. Holahan, and A. Routtenberg

Learning And Structural Plasticity

Hippocampal Granule Cell Axon Terminals And Learning

Mechanisms Of Presynaptic Structural Plasticity

The Presynaptic Disparity: Anti-Boutonism or a Biological Reality?

ELECTROPHYSIOLOGICAL REPRESENTATION OF TASTE MEMORY, T. Yamamoto and Y. Yasoshima

Introduction

CTA paradigm

Enhanced response to the CS

Alteration of responses reflecting hedonic shift

CS-US association

Importance of amygdala in CTA formation

Involvement of reward system

Summary

CHANGES IN NEUROTRANSMITTERS EXTRACELLULAR LEVELS DURING MEMORY FORMATION, M.I. Miranda

Introduction

The Free Moving Microdialysis Technique

Acetylcholine Release During Motor Activity, Attention, and Novelty

Novelty and Other Neurotransmitter Release

Lesions and Blockade of Cholinergic Activity During Memory Formation

Acetylcholine and Long Term Memory Tasks

Noradrenaline Release During Memory Formation

Glutamate and GABA Release During Memory Formation

Conclusions

REVERSIBLE BRAIN INACTIVATION OF BRAIN CIRCUITS IN LEARNING AND MEMORY RESEARCH, M. Gallo

Introduction

The Brain Lesion Approach and the Dynamic Nature of Learning and Memory Systems

Reversible Inactivation Techniques

Learning Behavioral Models and Reversible Inactivation Techniques

Dissociating Independent Learning and Memory Processes

Summary

ENHANCED LEARNING PROTECTS THE BRAIN AGAINST THE EFFECTS OF AMNESIC TREATMENTS, R.A. Prado-Alcalá, R. Salado-Castillo, C. Quiroz, M.E. Garín-Aguilar, A. Díaz-Trujillo, S. Rivas-Arancibia, and G.L. Quirarte

Introduction

Protective Effect of Enhanced Training

Two Models

Conclusions

References

STUDIES ON SHORT-TERM AVOIDANCE MEMORY, M. Cammarota, L.R.M. Bevilaqua, J.H. Medina, I. Izquierdo

Summary

Introduction

STM and LTM: Parallel or Sequential?

The Role of the Hippocampus in Avoidance STM and LTM

The Role of the Entorhinal Cortex in Avoidance STM and LTM

The Role of Other Cortical Areas and of the Amygdala in IA's Memory

Neurobiological Separation of Short and Long Term Avoidance Memory

STM and LTM are Behaviorally Different

The Biochemistry of Short Term Memory

Pharmacological Analysis of IA's Working Memory

Conclusions

References

MEMORY RECONSOLIDATION OR UPDATING CONSOLIDATION? C.J. Rodriguez-Ortiz and F. Bermudez-Rattoni

Abstract

The Consolidation Hypothesis

The Reconsolidation Era

On the Restraints of the Reconsolidation Hypothesis

Are Consolidation and Reconsolidation the Same Process?

The Reconsolidation Hypothesis Reconsidered: The Updating

Consolidation Proposal

Acknowledgments

References

MEMORY IMPAIRMENTS ASSOCIATED WITH STRESS AND AGING, C. Sandi

The Concept Of Stress

The Physiological Stress Response

Stress And Memory Function

Acute Stress And Memory Impairment

Neurobiological Mechanisms Involved In The Acute Effects Of Stress On Memory

Impairing Effects Of Chronic Stress On Cognitive Function

Neurobiological Mechanisms Involved In The Deleterious Effects Of Chronic Stress On Brain And Behavior

Stress And Aging

Aging

Memory Deficits In The Aging Human Population

Neurobiological Mechanisms Associated To Age-Related Cognitive Decline In Humans

Memory Deficits In Aged Rodents

Aging And Structural And Functional Plasticity

Conclusions

References

ADRENAL STRESS HORMONES AND ENHANCED MEMORY FOR EMOTIONALLY AROUSING EXPERIENCES, C.K. McIntyre and B. Roozendaal

Introduction

Stress Hormone Effects on Memory Consolidation

Stress Hormones Selectively Enhance Memory Consolidation of Emotionally Arousing Experiences

Involvement of the Amygdala in Mediating Stress Hormone Effects on Memory Consolidation

Role of Emotional Arousal-Induced Noradrenergic Activation Within the Amygdala in Enabling Epinephrine and Glucocorticoid Effects on Memory Consolidation

Conclusions

NEURO-IMMUNE ASSOCIATIVE LEARNING, G. Pacheco-López, M.-B. Niemi, H. Engler, and M. Schedlowski.

Abstract

Introduction

Phenomenon: The Association Between Exteroceptive and Immune Stimuli

Theoretical Framework for Neuro-Immune Associative Learning

Neurobiology of Neuro-Immune Associative Learning

Biological Relevance of Neuro-Immune Associative Learning

Clinical relevance of neuro-immune associative learning

Summary and future perspective

References

HUMAN BRAIN IMAGING STUDIES OF EMOTIONAL MEMORY: UNCOVERING INFLUENCES OF SEX AND HEMISPHERE, L. Cahill

Abstract

Introduction

The Amygdala-- Built to Modulate

Human Subject Studies Relating Amygdala Activity to Emotional Memory

An Aside on Sex Differences in the Brain

Sex-Related Influences on the Amygdala Relation to Memory for Emotional Events

Sex Difference in Human Amygdala Functional Connectivity at Rest

Potential Relationship of the Sex-Related Amygdala Hemispheric Specialization to Hemispheric Global/Local Processing Bias

Some Implications for Disease States

Summary

About the Series

Frontiers in Neuroscience

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Subject Categories

BISAC Subject Codes/Headings:
PSY000000
PSYCHOLOGY / General
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics
SCI089000
SCIENCE / Life Sciences / Neuroscience