276 Pages 39 B/W Illustrations
    by CRC Press

    Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments.

    It additionally contains sections explaining:

    • Applications of phyto-nanotechnology in neurological ailments,

    • Phytoconstituents related deep learning and machine learning-based solutions

    for neurological disorders,

    • Epigenetic relevance pertaining to modulation by phytochemicals.

    The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.

    Chapter 1

    Phytochemicals: Recent Trends Pertaining to Beneficial Effects on Neurological Disorders

    Sonam Pandey

    Chapter 2

    Neuroprotective Potentials of Phytochemicals

    Odangowei Inetiminebi Ogidi

    Imomotimi Ajoko

    Chapter 3

    Novel Extraction and Characterization Methods for Phytochemicals identified as Neuroprotective

    Umme Habiba Saeeda, Aneela Nawaz, Alina Majid, Muqaddas Shahzadi, Malik Badshah, Samiullah Khan

    Chapter 4

    The Neuroprotective Effect of Alkaloids and Synthetic Derivatives

    Likhit Akotkar, Aditya Ganeshpurkar, Ankit Ganeshpurkar

    Chapter 5

    Molecular Mechanism of Action of Phytoconstituents in Neuropsychiatric Disorders

    Urmila Aswar, Rashmi Patil, Likhit Akotkar, Atmaram Pawar

    Chapter 6

    The Role of Epigenetic Modifications by Phytoconstituents in Neurological Ailments

    Aarthi Narasimhan, Sri Raagavee Sivakumar, Karthikeyan Subbiahanadar Chelladurai, Kamarajan Rajagopalan, Jackson Durairaj Selvan Christyraj

    Chapter 7

    Applications of Phyto-nanotechnology in Neurological disorders

    Manoj Kumar Srinivasan, Nivedha Jayaseelan, Kanimozhi Kaliyamoorthi, Kamalesh Balakumar Venkatesan, Saravanan Alamelu, Sathish-Kumar Kamaraj

    Chapter 8

    Application of Neurophytomedicine for Protective Intervention and Remediation of Multiple Diseases

    Sumanta Bhattacharya

    Chapter 9

    Role of Phytopharmaceuticals as Adjuncts in Treatment of Glioblastoma Multiforme

    Ameya K, Rajesh Pradhan, Rajeev Taliyan

    Chapter 10

    Eugenol as Neuro-Phytomedicine: Recent Trends Pertaining to the treatment of Neurological Disorders

    Bhagawati Saxena

    Chapter 11

    Deciphering the Deep Learning and Machine Learning Tactics in Advancement of Neuroprotection by Phytochemicals.

    Shareena Gadde, Dileep Kumar

    Chapter 12

    Future Trends and Directives for Research on Phytochemicals in Neurological diseases

    Srishti Raja, Chandini Sengupta, Kamarajan Rajagopalan, Inbathamizh L, Sudha S, Jackson Durairaj Selvan Christyraj

    Index

    Biography

    Dr. Mithun Singh Rajput is working with Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India as a capacity of Assistant Professor. He has an expertise in neuropharmacology and received doctoral degree from Faculty of Medicine, M.G.M. Medical College, Indore, India. He is a recipient of two years’ National Postdoctoral Fellowship from SERB, Department of Science and Technology, India and associated with the research project as principal investigator. He has overall research experience of twelve years. His area of interest includes diagnosis and mitigating strategies for various neurodegenerative disorders like Alzheimer’s disease and cerebral ischemia, diabetes associated cognitive impairment etc. Mithun has one patent and three book chapters published and edited four books. Mithun has been credited with thirty publications in peer reviewed indexed journals and currently bagged with an h-index of sixteen. He has been serving many government funding agencies and journals and as a reviewer and editorial board member.

    Dr. Tewarit Sarachana is the Head of Chulalongkorn SYstems Neuroscience of Autism and PSychiatric disorders (SYNAPS) Research Unit. He is teaching at Department of Clinical Chemistry, Medical Technology Program, Faculty of Allied Health Sciences, Chulalongkorn University. He pursued doctoral degree in Neuroscience at School of Medicine and Health Sciences, The George Washington University, Washington DC, USA and received postdoctoral research training at The Office of Blood Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration (FDA), Bethesda, Maryland, USA. He also serves as a technical assessor for the medical laboratory standards ISO 15189:2012 and ISO 15190:2003, Bureau of Laboratory Quality Standards, Department of Medical Sciences, Ministry of Public Health, Thailand. He has handled more than twenty government funded research grants and supervised ample postdoctoral, doctoral and master’s candidates for their research. He has published more than thirty research articles, review articles, and book chapters, and is a reviewer for more than fifteen international journals, including Molecular Autism, Current Medicinal Chemistry, and Frontiers in Neuroscience.

    Prof. Purnima Dey Sarkar is serving as Head, Department of Biochemistry, M.G.M. Medical College, Indore, India and has a vast experience of teaching and research of forty years in various medical colleges of Madhya Pradesh, India. She received doctoral degree from Devi Ahilya Vishwavidyalaya, Indore, India in year 1991. Her area of interest in research includes biochemistry and pharmacology of various ailments viz. neurological and cardiovascular disorders, cancer and diabetes. She has supervised thirty Ph.D. candidates for their dissertation work. Also, she has been supervisor for fourteen M.D. candidates. She has more than seventy-five publications in journals of international and national repute and serving as reviewer for many funding agencies and journals. Prof. Sarkar has acquired various administrative responsibilities and served government universities as chairperson and member of board of studies, chairperson of various scientific committees, subject expert for faculty recruitment etc.

    Prof. Manan Raval is presently designated as Principal at Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, India. He received master’s and doctoral credentials from Maharaja Sayajirao University, Baroda, Gujarat. His area of interest includes chemistry of bioactive constituents isolated from natural products. Precisely, his research interest is on screening natural compounds for their efficacy in improving male infertility and exploring their molecular mechanisms. He exhibits vast academic, administrative and industrial experience. His work is regularly being presented and appreciated before a number of experts of national and international repute. Dr. Raval has received many project grants from various government agencies and supervised many doctoral and master’s candidates for their research work. He has published and presented ample research articles and serving the national and international scientific community in many capacities.