Neurobehavioral Genetics: Methods and Applications, Second Edition, 2nd Edition (Hardback) book cover

Neurobehavioral Genetics

Methods and Applications, Second Edition, 2nd Edition

Edited by Byron C. Jones, Pierre Mormede

CRC Press

496 pages | 6 Color Illus. | 88 B/W Illus.

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pub: 2006-08-30
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Description

A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source.

International researchers incorporate several new developments in the field, including:

  • Developmental neurobehavioral genetics

  • Gene-gene interaction

  • New approaches in bioinformatics

  • Gene expression

  • Single gene techniques

    Based on various studies of living organisms ranging from primates to rodents to invertebrates, this edition offers a contemporary approach to examining the relationship between the genetic mechanisms in the brain and behavior. The authors examine how past and recent advances in methods and knowledge come together in the comparative genetics of behavior. They introduce the reader to experimental approaches available for the genetic study of emotionality, focusing on the use of animal models.

    This edition explores studies in neurogenetic disorders, including schizophrenia and bipolar disorders, examines genetic traits in personality such as altruism, and evaluates aggression in mice and humans. It also discusses the applications of quantitative methods and molecular genetics in basic and clinical research.

    Neurobehavioral Genetics: Methods and Applications, Second Edition brings together new techniques and methods to promote a better understanding of genetics and their effects on behavior. The book is an excellent resource for investigators who want to incorporate genetic methods into neurobehavioral and psychiatric research.

  • Table of Contents

    Background and Basic Concepts

    A History of Behavior Genetics; Stephen C. Maxson

    Developmental Neurobehavioral Genetics: Development as Explanation; Gilbert Gottlieb

    Some Basics: Mendelian Traits, Polygenic Traits and Complex Traits; Byron C. Jones

    An Introduction to Quantitative Principles; Wim E. Crusio

    Methods

    From QTL Detection to Gene Identification; Marie-Pierre Moisan

    Gene expression; Richard A. Radcliffe

    Bioinformatics of Behavior; Elissa J. Chesler

    Congenic and Consomic Strains; Lorraine Flaherty and Valerie Bolivar

    Animal Resources in Behavioral Neurogenetics; Jean-Michel Lassalle

    Sample Size Requirements for Experiments on Laboratory Animals; Douglas Wahlsten

    Studies in Hominids

    Neurobehavioral Genetics: The Role of Association Studies in Psychiatric Disorders; Nicolas Ramoz and Phillip Gorwood

    Family and Twin Methods; Keith E. Whitfield

    Gene-environment interactions; Byron C. Jones and Leslie C. Jones

    And Now it Starts to Get Interesting: Gene-gene interactions; Yamima Osher

    Schizophrenia: Study of a Genetically Complex Phenotype; Michael Pogue-Geile and Irving Gottesman

    Genetics of Major Affective Disorders; Wade Berrettini

    Pedigree Analyses and the Study of Chimpanzee (Pan troglodytes): Personality and Subjective Well-Being; Alexander Weiss and James E. King

    The Elusive World of Personality Genes: Cherchez le phenotype; Richard P. Ebstein, Rachel Bachner-Melman, Jonathan Benjamin and Robert H. Belmaker

    Studies in Rodents

    Aggression: Concepts and Methods Relevant to Genetic Analyses in Mice and Humans; Stephen C. Maxson and Andrew Canastar

    Genetic Analysis of Emotional Behaviors Using Animal Models; André Ramos and Pierre Mormède

    Studies in Invertebrates

    Genetic Analysis of Food Search Behavior in the Fruit Fly (Drosophila melanogaster); Amsale T. Belay and Marla B. Sokolowski

    Genetic and Molecular Analysis of Drosophila Courtship Behavior; Jean-Marc Jallon

    A New Era for Drosophila Learning and Memory Studies; Daniel Comas, Guillaume Isabel, and Thomas Préat

    Behavioral Genetics in the Nematode Caenorhabditis Elegans; Gert Jensen and Laurent Ségalat

    Bridging Neurobiology and Behavior

    Genetics, Behavior and Brain Dopamine Systems; Robert Hitzmann, Shannon McWeeney, and John K. Belknap

    Natural Genetic Variation of Hippocampal Structures and Behavior; Hans-Peter Lipp, Irmgard Amrein, Lutz Slomianka, and David P. Wolfer

    Expression and Brain Structure: Black Boxes between Genes and Behaviors; Jeremy L. Peirce, Robert W. Williams

    Synaptic Mechanisms Involved in Cognitive Function: Cues From Mental Retardation Genes; Guntram Borck, Florence Molinari, Birgit Dreier, Peter Sonderegger and Laurence Colleaux

    Pharmacology

    Pharmacogenetics; Byron C. Jones

    Alcohol Psychopharmacogenetics; John C. Crabbe

    Subject Categories

    BISAC Subject Codes/Headings:
    MED105000
    MEDICAL / Psychiatry / General
    SCI029000
    SCIENCE / Life Sciences / Genetics & Genomics
    SCI089000
    SCIENCE / Life Sciences / Neuroscience