1st Edition

Non-melanoma Skin Cancer Essentials for Oncologists

Edited By Agata Rembielak, Luca Tagliaferri Copyright 2023
    454 Pages 216 Color & 9 B/W Illustrations
    by CRC Press

    454 Pages 216 Color & 9 B/W Illustrations
    by CRC Press

    This book provides a comprehensive introduction to the current state-of-the-art in skin cancer, exploring the recent developments, appraising the current evidence and providing future directions with particular emphasis on interdisciplinary collaboration and need for clinical trials. It covers all aspects of skin cancers, including epidemiology, pathology, surgical and non-surgical treatments.

    It will be a valuable reference for oncologists, dermatologists, dermatopathologists, surgeons, allied health care professionals and other specialists and trainees with a special interest in skin cancer who want to update their knowledge in the multidisciplinary management of such patients. The book will be of interest to medical physicists and radiographers who would like an overview of the current practice in skin cancer. The book can be used by students in medicine, nursing, radiography and medical physics.


    • Provides a comprehensive review of all aspects of skin cancer management.
    • Edited by experts in the area, with interdisciplinary and international collaborators.
    • Promotes a 'Bigger picture' approach to the topic with multidisciplinary insight.

    Chapter 1. Biology of Skin Invasion and Skin Metastases. Chapter 2. Chemoprevention and Photoprotection in Non-melanoma Skin Neoplasms. Chapter 3. Aetiology and Epidemiology of Non-melanoma Skin Neoplasms. Chapter 4. Clinical Presentation of Non-melanoma Skin Cancer and Selected Dermatological Manifestations.Chapter 5. Dermatopathology of Keratinocyte Tumours. Chapter 6.Dermatopathology of Merkel Cell Carcinoma, Cutaneous Lymphoma and Cutaneous Soft-Tissue Sarcoma. Chapter 7. Imaging in Non-melanoma Skin Neoplasms. Chapter 8. Skin Biopsy for Non-melanoma Skin Cancer. Chapter 9. Staging Systems in Non-melanoma Skin Neoplasms and Prognostication. Chapter 10: Topical, Ablative and Light-Based Therapies for Non-melanoma Skin Neoplasms. Chapter 11: Primary Excision and Surgical Reconstruction in Non-melanoma Skin Neoplasms. Chapter 12: Mohs Surgery. Chapter 13. Management of Nodal Metastases in Head and Neck Skin Squamous Cell Carcinomas. Chapter 14. Radiobiology of the Skin and Non-melanoma Skin Neoplasms. Chapter 15. Medical Physics and Planning in Skin Radiotherapy and Brachytherapy. Chapter 16. Radiotherapy to the Primary in Keratinocyte and Merkel Cell Cancers and to Skin Metastases. Chapter 17. Post-Operative Radiation Therapy for Keratinocyte Carcinoma and Merkell Cell Carcinoma. Chapter 18. Experiences when Irradiating Grafts and Flaps for Skin Cancer. Chapter 19. Skin Brachytherapy (Contact and Interventional Radiotherapy). Chapter 20. Early and Late Toxicity in Skin Brachytherapy. Chapter 21. Combined Radiotherapy and Systemic Treatment in Keratinocyte and Merkel Cell Carcinomas. Chapter 22. Radiotherapy in Cutaneous Lymphomas and Cutaneous Sarcomas. Chapter 23. Treatment of Locally Advanced and Metastatic Skin Carcinomas. Chapter 24. Systemic Treatment of Merkel Cell Carcinoma and Dermal Sarcomas. Chapter 25. Systemic Treatment of Cutaneous Lymphomas. Chapter 26. Management of Skin Cancer in the Immunocompromised Patient. Chapter 27. Dermatology and Oncology in Skin of Colour. Chapter 28. Skin Cancer Management in Elderly and Frail. Chapter 29. Quality of Life and Cosmetic Assessment in Skin Cancer Treatment. Chapter 30. Emerging Trends and Future Directions in Skin Cancer Management..


    Agata Rembielak, MD PhD, is an oncologist who focuses on the care of patients with skin cancer. She graduated from medicine and medical physics, followed by a specialist training in radiation oncology in Poland. She completed fellowships in Australia, Canada and UK. She subsequently was appointed a Clinical Oncology Consultant at The Christie Hospital in Manchester and an Honorary Clinical Senior Lecturer at The University of Manchester, UK. She is a member of the European SocieTy for Radiotherapy and Oncology (ESTRO) where she leads on skin brachytherapy and is a director on the multidisciplinary skin cancer course. Dr Rembielak co-authored British Association of Dermatology skin SCC guidelines and ESTRO guidelines on skin brachytherapy. In addition, she chairs the Skin Cancer in Older Patients taskforce for the International Society of Geriatric Oncology (SIOG). She serves on the editorial board of Clinical Oncology and Journal of Contemporary Brachytherapy.

    Luca Tagliaferri, MD,PhD, graduated in Medicine and surgery at "Università Cattolica del Sacro Cuore" in Rome, followed by radiation oncology fellowship. In 2018 he obtained the associate professor qualification and in 2021 the full professor qualification (ASN - National Scientific Qualification). Dr Tagliaferri is the head of the Interventional Radiotherapy Unit at the Gemelli-ART (Advanced Radiation Therapy) at Policlinico Universitario Agostino Gemelli-IRCCS(Rome). The focus of his clinical and research activities is head&neck, skin, gynaecological and prostate cancer.In addition, he is involved in teaching and in medical software development that supports research and clinical practice with special focus on Artificial intelligence . At European Society for Radiotherapy and Oncology He chairs the Head&Neck and Skin GEC-ESTRO Working Group and is a member of GEC-ESTRO committee and guidelines committee. At the Italian Association of Radiation and Clinical Oncology (AIRO) he coordinated activities of the Metabolic Radiotherapy (2015-16) and the Interventional Radiotherapy Working Groups (2018-19), currently He is member of AIRO executive board. His research and clinical activity have led to more than 150 papers in peer-reviewed scientific journals and book chapters. He is on editorial board of the Journal of Contemporary Brachytherapy and Brachytherapy.