1st Edition

Noradrenergic Mechanisms in Parkinson's Disease

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ISBN 9780849383915
Published December 16, 1993 by CRC Press
288 Pages

USD $450.00

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Book Description

Noradrenergic Mechanisms in Parkinson's Disease examines fundamental and clinical evidence explaining the progression of the disease. Featuring contributions from acknowledged international experts in the field, this book defines ideopathic Parkinson's disease and covers such topics as the alterations in Parkinson's disease, norepinephrine-dopamine interactions, noradrenergic control of striatal dopamine release, glial cells as targets of the central noradrenergic systems, and a theory regarding noradrenergic mechanisms in Parkinson's disease. New directions for research on Parkinson's disease are also explored.

Table of Contents

The Contributors
Defining Ideopathic Parkinson's Disease, J.M. Gybles
The Validity of the MPTP Primate Model for the Neurochemical Pathology of Idiopathic Parkinson's Disease, O. Hornykiewicz and C. Pifl
Recovery from MPTP-Induced Parkinsonian Manifestations Following Locus Coereleus Lesions in Squirrel Monkeys, M. Mavridis
The Possible Role of Noradrenergic Deficits in Selected Signs of Parkinson's Disease, M. Gerlach, K. Jellinger, and P. Riederer
Anatomy of the Noradrenergic Pathways in the Primate Brain: Alterations in Parkinson's Disease, P. Gaspar
The Locus Coeruleus in Parkinson's Disease,
R. Raisman-Vozari
Interactions between Noradrenaline and Dopamine Neurotransmission in the Rat Prefrontal Cortex and Their Consequences on Dopaminergic Subcortical Function, J.P. Tassin, F. Trovero, G. Blanc,
D. Hervé, and J. Glowinski
Norepinephrine-Dopamine Interactions: One Step Beyond, S.M. Antelman and A.R. Caggiula
Noradrenergic Control of Striatal Dopamine Release, M. Marien, A. Lategan, and F. Colpaert
The Effects of a2 Adrenoceptor Antagonists on Extracellular Dopamine Concentrations in Rat Striatum, D. Nutt, M. Lalies, and A. Hudson
Glial Cells as Targets of the Central Noradrenergic System-An Update., E.A. Stone
Adrenergic Activation of Phospholipase C in Striatal Astrocytes: Neurotransmitter Interactions, M. El-Etr
Noradrenergic Control of Gap Junction Permeability in Cultured Striatal Astrocytes, C. Giaume
Noradrenergic Mechanisms in Parkinson's Disease: A Theory, F.C. Colpaert

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