Nuclear Medicine Physics: 1st Edition (Paperback) book cover

Nuclear Medicine Physics

1st Edition

Edited by Joao Jose De Lima

CRC Press

524 pages | 221 B/W Illus.

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Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics.

The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it describes the use of radiopharmaceuticals in molecular imaging, clinical, and research studies. The text then covers modern radiation detectors and measuring methods, including those used in nuclear imaging, as well as numerous imaging methodologies and models, such as two- and three-dimensional image reconstruction algorithms, data processing sequences, new nuclear oncology techniques, and physiological models of the central nervous system. It also introduces biological systems theory, nuclear medicine methods as systems theory procedures, and aspects of kinetic modeling. The final chapter explores dosimetry and the biological effects of ionizing radiation.

With many new developments occurring in nuclear medicine, it is important to understand how advanced approaches are being used in emerging applications. Offering invaluable insight into this growth, Nuclear Medicine Physics provides in-depth descriptions of new radiolabeled biological drugs, new cell labeling techniques, new technical concepts in radiation detection, improvements in instrumentation, and much more.


… The data contained here will no doubt prove vital to researchers in multiple disciplines (physics, nuclear medicine, oncology) looking for ways to expand and upgrade patient care (specifically, oncologists charged with diagnosing and treating various forms of cancer will immediately benefit from learning how nuclear imaging techniques can enhance the patient experience in the clinical setting).

The Electric Review, January 2011

Table of Contents

Introduction, J.J. Pedroso de Lima

Cyclotron and Radionuclide Production, Francisco J.C. Alves

The Quantitative Aspects of Radionuclide Production

The Cyclotron: Physics and Acceleration Principles

Positron Physics, Adriano Pedroso de Lima and Paulo M. Gordo

The Physical and Chemical Aspects of the Positron and Positronium in Matter

Perspectives on the Medical Applications of Positrons

Radiopharmaceuticals: Development and Main Applications, Antero Abrunhosa and M. Isabel Prata

Radiochemistry and Radiopharmacy in Conventional Nuclear Medicine and PET

Advances in Radiopharmacy and New Trends in Radiochemistry

Radiation Detectors and Image Formation, Francisco J. Caramelo, Carina Guerreiro, Nuno C. Ferreira, and Paulo Crespo

The Physics of Detection Methods

Instrumentation in Nuclear Medicine Imaging: SPECT and PET

Imaging Methodologies, Nuno C. Ferreira, Francisco J. Caramelo, J.J. Pedroso de Lima, Carina Guerreiro, M. Filomena Botelho, Durval C. Costa, Hélder Araújo, and Paulo Crespo

Physical Aspects of the Image in Nuclear Medicine

Reconstruction and Data and Image Processing in Nuclear Medicine

Advanced Methods in Nuclear Oncology

The Central Nervous System: Physiological Models and Clinical Applications

Systems in Nuclear Medicine, J.J. Pedroso de Lima, and António Dourado

Biological Systems Theory and Kinetic Modeling of Radiotracers

Dosimetry and Biological Effects of Radiation, Augusto D. Oliveira and J.J. Pedroso de Lima

Ionizing Radiations: Physics, Dosimetry, and Protection

The Physics of the Biological Effects of Radiation

Nontargeted Effects: Another Option for Low-Dose Radiation Action


About the Editor

João José Pedroso de Lima is a professor emeritus of biophysics at the University of Coimbra in Portugal, where he was president of the executive board of the Institute of Biomedical Research in Light and Image (IBILI). Dr. Lima has published numerous papers and has received over twenty scientific awards, including an honorary degree by the University of Aveiro. His main research interests include nuclear medicine physics, biomedical systems, and biophysics of respiration.

About the Series

Series in Medical Physics and Biomedical Engineering

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Radiology & Nuclear Medicine
SCIENCE / Physics