Nutraceuticals and Functional Foods in Human Health and Disease Prevention  book cover
1st Edition

Nutraceuticals and Functional Foods in Human Health and Disease Prevention

ISBN 9781482237214
Published October 15, 2015 by CRC Press
722 Pages 8 Color & 92 B/W Illustrations

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Book Description

Functional foods and nutraceuticals, dietary supplements, and natural antioxidants have established their potential roles in the protection of human health against disease. Nutraceuticals and Functional Foods in Human Health and Disease Prevention examines the benefits, efficacy, and success of properly designed nutraceuticals and functional foods in human health and their possible application in disease prevention. The book demonstrates diverse disease pathophysiology and how nutraceuticals and functional food can be used to combat and prevent disease.

The book discusses global food habits and trends, safety and toxicology, and how food addiction or overindulgence of food can lead to a variety of disease states. It then highlights how supplements help in disease prevention. Although a significant number of nutraceuticals and functional foods have demonstrated their efficacy, a large number of supplements are still surviving on false claims. Therefore, the editors underscore risks and benefits, and why government regulatory agencies are so critical of these nutraceutical supplements.

With the global nutraceuticals market expected to reach $204.8 billion by 2017, what once seemed a very niche sector has become big business. An overview of nutraceuticals and functional foods and their application in human health, this book exhaustively covers antioxidants, functional foods, and nutraceuticals in human health and disease prevention. With contributions from experts and pioneers, the book gives insight into the role of functional foods in optimal diet and exercise.

Table of Contents

Global Food Habit and Trend: An Overview

Priyamvadah Kinth and Nimisha Kankan
Safety and Toxicity of Functional Foods and Nutraceuticals
Palma Ann Marone and Kathryn Birkenbach
Functional Foods in the Treatment of Proceßed Food Addiction and the Metabolic Syndrome
J.R. Ifland, Harry G. Preuss, M.T. Marcus, K.M. Rourke, W.C. Taylor, H. Theresa Wright, and K. Sheppard
Nutraceuticals and Their Role in Human Health: A Review
Runu Chakraborty and Lipi Das

Dietary Factors in Promoting Healthy Lifestyle: A New Prospect of Neuroendocrine in Obesity
Richard Zwe-Ling Kong
Health Effects and Weight Loss Benefits of Calorie Restriction Dietary Regimens
Eric Gumpricht and Krista Varady
Overview of Novel Herbal Supplements in Diabetes
Neetu Mishra, Kanti Bhooshan Pandey, and Syed Ibrahim Rizvi
Recommended Diet for Diabetics: Hydrocarbons, Glycemic Impact, Glycemic Load, Glycemic Index, and Mediterranean Diet
Paulin Moszczyåński and Zbigniew Tabarowski

Nutrition and Cardiovascular Health: A Review
Mash Hamid, Clare Stradling, Shahrad Taheri, and G. Neil Thomas

Antioxidative and Anti-Inflammatory Effects and Health Implications of Berry Polyphenols: Evidence from Compositional and Structural Background to Cell, Animal, and Human Studies
Sang Gil Lee, Terrence M. Vance, and Ock K. Chun
A Review on the Efficacy of Probiotics in the Treatment of Rheumatic Diseases
Elnaz Vaghef-Mehrabany and Leila Vaghef-Mehrabany
Phytochemicals as Anti-Inflammatory Agents
Kartick C. Pramanik and Atreyi Maiti

ω-3 PUFA Fatty Acids, Advancing Age, and Brain Function: A Review
Isabelle Denis and GaËlle Champeil-Potokar
Stress, Parkinson’s, and Alzheimer’s Disease: Role of Dietary Supplements
Raj K. Keservani, Rajesh K. Kesharwani, Anil K. Sharma, and Mohd Fasih Ahmad
Nutraceuticals and Functional Foods in the Prevention of Mental Disorder
Raj K. Keservani, Swati Singh, Virendra Singh, Rajesh K. Kesharwani, and Anil K. Sharma

Prebiotics, Probiotics, and Synbiotics for the Management of Respiratory Disease
Seil Sagar, Gert Folkerts, and Johan Garssen
Pulmonary and Respiratory Health: Antioxidants and Nutraceuticals
Raj K. Keservani, Rajesh K. Kesharwani, and Anil K. Sharma

Nutrition and Nutraceutical Supplements for the Treatment of Hypertension
Mark Houston
Effects of Different Dietary Fibers on Sugar-Induced Blood Preßure Elevations in Hypertensive Rats: Focus on Viscosity
Harry G. Preuß, Debasis Bagchi, Dallas Clouatre, and Nicholas V. Perricone

Dietary Supplements, Nutraceutical, and Functional Foods in Immune Response (Immunomodulators)
Raj K. Keservani, Rajesh K. Kesharwani, Anil K. Sharma, and Urmila Jarouliya

Natural Products in the Prevention of Cancer: A Review
Kelly C. Heim and Michael J. Spinella
Helicobacter pylori Infection and Phytochemicals
Archana Chatterjee

Integrative View of the Nutrition of the Eye
S.K. Polutchko, J.J. Stewart, and B. Demmig-Adams

Nutraceuticals for Prostate Cancer
Shigeo Horie

Nutrition and Sleep: An Overview
Glenda Lindseth, Ashley Murray, and Brian Helland

Oral Supplementation of a Standardized Naturally Fermented Papaya Preparation May Correct Type 2 Diabetes Mellitus-Induced Reactive Oxygen Species Dysregulation
Ryan Dickerson and Sashwati Roy

Herbal Treatment for Hair Loss and Alopecia: An Overview
Nattaya Lourith and Mayuree Kanlayavattanakul
Nutrition, Nutraceuticals, and Hair Growth
Mi-Ryung Kim and Jae-Suk Choi
Herbal Treatment for Skin Wrinkle: An Overview
Mayuree Kanlayavattanakul and Nattaya Lourith

Nutraceuticals and Male Fertility: A Review
Michelle Lightfoot, Muhannad Alsyouf, and Edmund Y. Ko
Sexual Dysfunctions and Nutraceutical Therapy: An Examination of Human Research
Gene Bruno

Nutraceuticals in Cosmeceuticals
Palma Ann Marone

Nutrition, Functional Foods, and Exercise: A Review
Wataru Aoi and Yuji Naito

Nutraceuticals in the Management of Sickle Cell Anemia
Ngozi Awa Imaga

Health Benefits of Human Probiont Lactobacillus plantarum
Satish Kumar Ramraj and Arul Venkatesan
Probiotic in Functional Gastrointestinal Disorders in Children: Therapy and Revention
Flavia Indrio, Giuseppe Riezzo, and Antonio Di Mauro
Probiotics and Dental Health: An Overview
Maria Grazia Cagetti, Fabio Cocco, and Guglielmo Campus
Antimicrobial Properties of Wild Oregano Extracts: A Compilation and Review of Current Research
Cassim Igram
Nutraceuticals from Microalgae
Faruq Ahmed, Faisal Alsenani, and Peer M. Schenk

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Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his PhD in medicinal chemistry in 1982. He is a professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, Texas, and the chief scientific officer of Cepham Research Center, Piscataway, New Jersey. Dr. Bagchi is an adjunct faculty in Texas Southern University, Houston, Texas. He served as the senior vice president of research and development of InterHealth Nutraceuticals Inc, Benicia, California, from 1998 until February 2011, and then as director of innovation and clinical affairs, of Iovate Health Sciences, Oakville, Ontario, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the past chairman of International Society of Nutraceuticals and Functional Foods, immediate past president of the American College of Nutrition, Clearwater, Florida, and past chair of the Nutraceuticals and Functional Foods Division of the Institute of Food Technologists, Chicago, Illinois. He is serving as a distinguished advisor on the Japanese Institute for Health Food Standards, Tokyo, Japan. Dr. Bagchi is a member of the Study Section and the Peer Review Committee of the National Institutes of Health, Bethesda, Maryland.
Dr. Bagchi has 304 papers in peer-reviewed journals, 26 books, and numerous patents. He has delivered invited lectures in various national and international scientific conferences and organized workshops, and group discussion sessions. Dr. Bagchi is also a member of the Society of Toxicology, member of the New York Academy of Sciences, fellow of the Nutrition Research Academy, and member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, Ohio. He is the associate editor of the Journal of Functional Foods, Journal of the American College of Nutrition, and Archives of Medical and Biomedical Research, and also serves as editorial board member of numerous peer-reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist.

Dr. Anand Swaroop earned his MS in biochemistry and PhD in chemistry in 1997. He has gathered over two decades of diversified global management experience in phytopharmaceuticals, global regulations on nutraceuticals and functional foods, chemicals and pharmaceutical ingredients, outsourcing and supply chain management, business development, market research, and strategic planning. He has worked in various multinational pharmaceutical companies including Alembic Ltd. (Vadodara, India), Cadila Laboratories Ltd. (Ahmedabad, India), Nandesari Rasayanee Ltd. (Vadodara, India), Dai-Ichi Laboratories Ltd. (Hyderabad, India), and Yag Mag Labs Pvt. Ltd. (Hyderabad, India) in senior management positions.
Currently, he is the founder president of Cepham Inc., Yag Mag Inc., and RALLIFE Inc. (Piscataway, New Jersey) and Cepham Life Sciences Inc. (MD). Dr. Swaroop has several peer-reviewed publications. He is a member of the American Chemical Society (ACS), American Association of Pharmaceutical Scientists (AAPS), American Society of Pharmacognosy (ASP), Council for Responsible Nutrition (CRN), American Botanical Council (ABC), and Natural Products Association (NPA). Dr. Swaroop has organized and chaired numerous sessions in the annual meetings of the Institutes of Food Technologists (IFT) and International Society of Nutraceuticals and Functional Foods (ISNFF) and other scientific meetings. He has also delivered invited lectures in various national and international scientific conferences, organized workshops, and group discussion sessions.

Harry G. Preuss, MD, MACN, CNS, received his BA and MD from Cornell University, Ithaca, New York, and New York City, New York; trained for three years in internal medicine at Vanderbilt University Medical Center under Dr. David E. Rogers; studied for two years as a fellow in renal physiology at Cornell University Medical Center under Dr. Robert F. Pitts; and spent two years in clinical and research training in nephrology at Georgetown University Medical Center under Dr. George E. Schreiner. During his training years, he was a special research fellow of the National Institutes of Health (NIH). Following the five years as an assistant and associate (tenured) professor of medicine at the University of Pittsburgh Medical Center where he became an established investigator of the American Heart Association, he returned to Georgetown Medical Center. He subsequently performed a six-month sabbatical in molecular biology at the NIH in the laboratories of Dr. Maurice Burg. Dr. Preuss is now a tenured professor in four departments at Georgetown University Medical Center—biochemistry, physiology, medicine, and pathology.
His bibliography includes more than 240 peer-reviewed, original medical research papers, 200 general medical contributions (chapters, review articles, etc.), 7 patents, and more than 250 abstracts. Dr. Preuss has written, edited, or coedited nine books and three symposia published in well-established journals. In 1976, Dr. Preuss was elected to membership in the American Society for Clinical Investigations on the first attempt. He is currently an advisory editor for many journals.
His previous government appointments included four years on the Advisory Council for the National Institute on Aging, two years on the Advisory Council of the Director of the NIH (NIA Representative), and two years on the Advisory Council for the Office of Alternative Medicine of the NIH. He has been a member of many other peer research review committees for the NIH and American Heart Association and was recently a member of the National Cholesterol Education Program of the NHLBI and clinical study section JH-07 of the NIH.
Dr. Preuss was elected the ninth Master of the American College of Nutrition (ACN). He is a former chairman of two ACN councils—Cardiovascular/Aging and Dietary Supplements/Functional Foods. After a brief stint on the BOD of the ACN, Dr. Preuss spent three years as secretary-treasurer and three consecutive years as vice president, president-elect, and became president in 1998.
In 2008 and 2010, he was twice reelected president of the ACN, the only person to hold this office more than once. Dr. Preuss is a member of the board of directors for the Alliance for Natural Health (ANH-USA) and was made a member of the ANH-INT Scientific and Medical collaboration group. Dr. Preuss wrote the nutrition section for the Encyclopedia Americana and is past president of the Certification Board for Nutrition Specialists (CBNS) that gives the CNS certification. He was chairman of the Institutional Review Board (IRB) at Georgetown University, which reviews all clinical protocols at Georgetown University Medical Center, for over 20 years. Dr. Preuss is currently chairman of the Scientific Advisory Board for He is the recipient of the Harold Harper Lectureship Award (ACAM), William B. Peck, James Lind, and Bieber Awards for his research and activities in the medical and nutrition fields. His current research, both laboratory and clinical, centers on the use of dietary supplements to favorably influence or even prevent a variety of medical perturbations, especially those related to obesity, insulin resistance, and cardiovascular disorders.
Lately, he has also researched the ability of many natural products to overcome various infections, including those resistant to antibiotics. He won through a vote of his peers the coveted Charles E. Ragus Award of the ACN for publishing the best research paper in their journal for 2006 and the ACN Award for 2010 given to an outstanding senior investigator in nutrition. In 2014, he received the Jonathan Emord Awards for his research in the fields of medicine, nutrition, and integrative medicine.